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Biology and Biochemistry

D-Index
72
Citations
22254
World Ranking
6195
National Ranking
400

Overview

Norihiro Kato is affiliated with the National Center For Global Health and Medicine in Japan. Their research spans multiple fields within medicine, biochemistry, genetics, and molecular biology, with a focus on molecular biology, genetics, cardiology and cardiovascular medicine, endocrinology, diabetes and metabolism, and epidemiology.

The scientist's recent publications reflect a focus on genetic associations and epidemiology, hormonal regulation and hypertension, and the renin-angiotensin system among other topics. Significant recent papers include:

  • Identification of type 2 diabetes loci in 433,540 East Asian individuals (2020, Nature)
  • A polygenic risk score improves risk stratification of coronary artery disease: a large-scale prospective Chinese cohort study (2022, European Heart Journal)
  • Identification of genetic effects underlying type 2 diabetes in South Asian and European populations (2022, Communications Biology)
  • SLC15A4 mediates M1-prone metabolic shifts in macrophages and guards immune cells from metabolic stress (2021, Proceedings of the National Academy of Sciences)
  • Lectin-Like Oxidized Low-Density Lipoprotein Receptor-1-Related Microglial Activation in Neonatal Hypoxic-Ischemic Encephalopathy (2021, American Journal Of Pathology)

The main topics of Kato's work cover a variety of areas, including genetic associations and epidemiology, hormonal regulation and hypertension, renin-angiotensin system studies, liver disease diagnosis and treatment, RNA modifications and cancer, neuroinflammation and neurodegeneration mechanisms, and bioinformatics and genomic networks.

  • Genetic Associations and Epidemiology
  • Hormonal Regulation and Hypertension
  • Renin-Angiotensin System Studies
  • Liver Disease Diagnosis and Treatment
  • RNA modifications and cancer
  • Neuroinflammation and Neurodegeneration Mechanisms
  • Bioinformatics and Genomic Networks

The scientist has collaborated frequently with several co-authors, including Fumihiko Takeuchi, Masato Isono, Yi-Qiang Liang, Ching-Yu Cheng, and Tien Yin Wong.

  • Fumihiko Takeuchi
  • Masato Isono
  • Yi-Qiang Liang
  • Ching-Yu Cheng
  • Tien Yin Wong

Norihiro Kato's work has been published in a variety of venues, with multiple papers appearing in bioRxiv (Cold Spring Harbor Laboratory). Other frequent publication venues include the Journal of Hypertension, International Heart Journal, Nature, and European Heart Journal.

  • bioRxiv (Cold Spring Harbor Laboratory)
  • Journal of Hypertension
  • International Heart Journal
  • Nature
  • European Heart Journal

The diversity in research topics and publication outlets highlights a multidisciplinary approach, covering aspects of endocrinology, cardiovascular research, genomics, and immunology within the broader medical and biological sciences.

Best Publications

  • Novel genetic associations for blood pressure identified via gene-alcohol interaction in up to 570K individuals across multiple ancestries

    Mary F. Feitosa;Aldi T. Kraja;Daniel I. Chasman;Yun J. Sung

  • Genome-wide trans-ancestry meta-analysis provides insight into the genetic architecture of type 2 diabetes susceptibility.

    Anubha Mahajan;Min Jin Go;Weihua Zhang;Jennifer E. Below

  • The trans-ancestral genomic architecture of glycemic traits

    Ji Chen;Ji Chen;Cassandra N. Spracklen;Cassandra N. Spracklen;Gaëlle Marenne;Gaëlle Marenne;Arushi Varshney

  • Epigenome-wide association study of body mass index, and the adverse outcomes of adiposity

    Simone Wahl;Alexander Drong;Benjamin Lehne;Marie Loh;Marie Loh;Marie Loh

  • Meta-analysis of genome-wide association studies identifies eight new loci for type 2 diabetes in east Asians

    Yoon Shin Cho;Chien Hsiun Chen;Chien Hsiun Chen;Cheng Hu;Jirong Long

  • Meta-analysis of genome-wide association studies identifies common variants associated with blood pressure variation in east Asians

    Norihiro Kato;Fumihiko Takeuchi;Yasuharu Tabara;Tanika N. Kelly

  • Genome-wide association study in individuals of South Asian ancestry identifies six new type 2 diabetes susceptibility loci

    Jaspal S Kooner;Danish Saleheen;Xueling Sim;Joban Sehmi;Joban Sehmi

  • Genome-wide association analysis identifies novel blood pressure loci and offers biological insights into cardiovascular risk

    Helen R Warren;Evangelos Evangelou;Evangelos Evangelou;Claudia P Cabrera;He Gao

  • Genetic associations at 53 loci highlight cell types and biological pathways relevant for kidney function

    Cristian Pattaro;Alexander Teumer;Mathias Gorski;Audrey Y. Chu

  • Epigenome-wide association of DNA methylation markers in peripheral blood from Indian Asians and Europeans with incident type 2 diabetes: a nested case-control study.

    John C Chambers;Marie Loh;Marie Loh;Marie Loh;Benjamin Lehne;Alexander Drong

  • Meta-analysis identifies common variants associated with body mass index in east Asians

    Wanqing Wen;Yoon Shin Cho;Wei Zheng;Rajkumar Dorajoo;Rajkumar Dorajoo

  • Characteristics and outcomes of hospitalized patients with heart failure and reduced vs preserved ejection fraction. Report from the Japanese Cardiac Registry of Heart Failure in Cardiology (JCARE-CARD).

    Miyuki Tsuchihashi-Makaya;Sanae Hamaguchi;Shintaro Kinugawa;Takashi Yokota

  • Impact of common genetic determinants of Hemoglobin A1c on type 2 diabetes risk and diagnosis in ancestrally diverse populations: A transethnic genome-wide meta-analysis

    Eleanor Wheeler;Aaron Leong;Ching-Ti Liu;Marie-France Hivert

  • Trans-ancestry genome-wide association study identifies 12 genetic loci influencing blood pressure and implicates a role for DNA methylation

    Norihiro Kato;Marie Loh;Marie Loh;Marie Loh;Fumihiko Takeuchi;Niek Verweij

  • Identification of type 2 diabetes loci in 433,540 East Asian individuals

    Cassandra N Spracklen;Cassandra N Spracklen;Momoko Horikoshi;Young Jin Kim;Kuang Lin

  • Meta-analysis identifies multiple loci associated with kidney function–related traits in east Asian populations

    Y. Okada;X. Sim;X. Sim;M. J. Go;J. Y. Wu;J. Y. Wu

  • Multiancestry genome-wide association study of 520,000 subjects identifies 32 loci associated with stroke and stroke subtypes

    Rainer Malik;Ganesh Chauhan;Matthew Traylor;Muralidharan Sargurupremraj

  • Trans-ancestry genetic study of type 2 diabetes highlights the power of diverse populations for discovery and translation

    Mahajan A;Spracklen Cn;Zhang W;Ng Mc

  • Genome-wide association analysis identifies novel blood pressure loci and offers biological insights into cardiovascular risk (vol 49, pg 403, 2017)

    HR Warren;E Evangelou;CP Cabrera;H Gao

  • Genome-wide trans-ancestry meta-analysis provides insight into the genetic architecture of type 2 diabetes susceptibility

    Anubha Mahajan;Min Jin Go;Weihua Zhang;Jennifer E. Below

Frequent Co-Authors

Fumihiko Takeuchi
Fumihiko Takeuchi Juntendo University
Jianjun Liu
Jianjun Liu Genome Institute of Singapore
Tien Yin Wong
Tien Yin Wong Tsinghua University
John C. Chambers
John C. Chambers Guy's and St Thomas' NHS Foundation Trust
Tomohiro Katsuya
Tomohiro Katsuya Osaka University
Jaspal S. Kooner
Jaspal S. Kooner Imperial College London
Yik Ying Teo
Yik Ying Teo National University of Singapore
Weihua Zhang
Weihua Zhang Imperial College London
Chiea Chuen Khor
Chiea Chuen Khor Agency for Science, Technology and Research
Xueling Sim
Xueling Sim National University of Singapore

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