2026 Fabrizio De Benedetti: Immunology Researcher – H-Index, Publications & Awards

Discipline name	D-Index	World Ranking	Current World Ranking	National Ranking	Current National Ranking	Publications	Citations
Immunology	73	2128	1953	85	81	350	20849

Research.com Recognitions

2010 - Member of Academia Europaea

Overview

Fabrizio De Benedetti is affiliated with Bambino Gesù Children's Hospital in Italy and has a research focus primarily in the field of Medicine. Their work spans several subfields, including Hematology, Immunology, Speech and Hearing, Molecular Biology, and Rheumatology.

The scientist's research topics cover a range of areas related to immune and inflammatory processes, including:

Autoimmune and Inflammatory Disorders Research
Adolescent and Pediatric Healthcare
Inflammasome and immune disorders
Immune Cell Function and Interaction
Kawasaki Disease and Coronary Complications
Immunodeficiency and Autoimmune Disorders
Acute Lymphoblastic Leukemia research

Among recent publications, Fabrizio De Benedetti has contributed to important papers such as:

"Translating IL-6 biology into effective treatments," published in 2020 in Nature Reviews Rheumatology
"On the Alert for Cytokine Storm: Immunopathology in COVID-19," published in 2020 in Arthritis & Rheumatology
"Emapalumab in Children with Primary Hemophagocytic Lymphohistiocytosis," published in 2020 in New England Journal of Medicine
"Meta-analysis of neural systems underlying placebo analgesia from individual participant fMRI data," published in 2021 in Nature Communications
"Targeting interferon-γ in hyperinflammation: opportunities and challenges," published in 2021 in Nature Reviews Rheumatology

Frequent co-authors who have collaborated extensively with Fabrizio De Benedetti include Claudia Bracaglia, Antonella Insalaco, Alexei A. Grom, Manuela Pardeo, and Ivan Caiello.

The scientist's work has appeared repeatedly in several publication venues, reflecting prominent areas of focus in rheumatology and pediatric medicine. These venues include:

Annals of the Rheumatic Diseases
Pediatric Rheumatology
Neuroscience Applied
Lara D. Veeken
Arthritis & Rheumatology

Fabrizio De Benedetti was recognized as a Member of Academia Europaea in 2010, an indication of their contributions to the scientific community.

Best Publications

Updated consensus statement on biological agents for the treatment of rheumatic diseases, 2010

D. E. Furst;E. C. Keystone;J. Braun;F. C. Breedveld

1079
Citations
Drug Retention Rate and Predictive Factors of Drug Survival for Interleukin-1 Inhibitors in Systemic Juvenile Idiopathic Arthritis.

Jurgen Sota;Antonella Insalaco;Rolando Cimaz;Maria Alessio

948
Citations
Randomized trial of tocilizumab in systemic juvenile idiopathic arthritis.

Fabrizio De Benedetti;Hermine I. Brunner;Nicolino Ruperto;Andrew Kenwright

921
Citations
Interleukin 6 is required for the development of collagen-induced arthritis.

Tonino Alonzi;Elena Fattori;Domenico Lazzaro;Patrizia Costa

782
Citations
2016 Classification criteria for macrophage activation syndrome complicating systemic juvenile idiopathic arthritis: A European league against Rheumatism/American college of Rheumatology/Paediatric rheumatology international trials organisation collaborative initiative

Angelo Ravelli;Francesca Serena Minoia;Sergio Davi;Anna Carin Horne

763
Citations
On the Alert for Cytokine Storm: Immunopathology in COVID-19.

Lauren A Henderson;Scott W Canna;Grant S Schulert;Stefano Volpi

690
Citations
Translating IL-6 biology into effective treatments.

Ernest Hs Choy;Fabrizio De Benedetti;Tsutomu Takeuchi;Misato Hashizume

637
Citations
Classification criteria for autoinflammatory recurrent fevers

Marco Gattorno;Michael Hofer;Silvia Federici;Federica Vanoni

522
Citations
Emapalumab in Children with Primary Hemophagocytic Lymphohistiocytosis

Franco Locatelli;Michael B. Jordan;Carl Allen;Simone Cesaro

489
Citations
Canakinumab for the Treatment of Autoinflammatory Recurrent Fever Syndromes

Fabrizio De Benedetti;Marco Gattorno;Jordi Anton;Eldad Ben-Chetrit

482
Citations
Macrophage activation syndrome in the era of biologic therapy.

Alexei A. Grom;Anna Carin Horne;Fabrizio de Benedetti

448
Citations
Correlation of Serum Interleukin-6 Levels with Joint Involvement and Thrombocytosis in Systemic Juvenile Rheumatoid Arthritis

Fabrizio de Benedetti;Margherita Massa;Piera Robbioni;Angelo Ravelli

436
Citations
2016 Classification Criteria for Macrophage Activation Syndrome Complicating Systemic Juvenile Idiopathic Arthritis

Angelo Ravelli;Francesca Minoia;Sergio Davì;Annacarin Horne

400
Citations
Impaired skeletal development in interleukin-6-transgenic mice: a model for the impact of chronic inflammation on the growing skeletal system.

Fabrizio De Benedetti;Nadia Rucci;Andrea Del Fattore;Barbara Peruzzi

368
Citations
Treating juvenile idiopathic arthritis to target: recommendations of an international task force

Angelo Ravelli;Alessandro Consolaro;Gerd Horneff;Ronald M Laxer

364
Citations
NGF and Its Receptors in the Regulation of Inflammatory Response.

Gaetana Minnone;Fabrizio De Benedetti;Luisa Bracci-Laudiero

346
Citations
Elevated circulating levels of interferon-γ and interferon-γ-induced chemokines characterise patients with macrophage activation syndrome complicating systemic juvenile idiopathic arthritis

Claudia Bracaglia;Kathy de Graaf;Denise Pires Marafon;Florence Guilhot

336
Citations
Mutation screening of the macrophage migration inhibitory factor gene: positive association of a functional polymorphism of macrophage migration inhibitory factor with juvenile idiopathic arthritis.

Rachelle Donn;Zaynab Alourfi;Fabrizio De Benedetti;Cristina Meazza

327
Citations
Efficacy and safety of tocilizumab in patients with polyarticular-course juvenile idiopathic arthritis: results from a phase 3, randomised, double-blind withdrawal trial

Hermine I Brunner;Nicolino Ruperto;Zbigniew Zuber;Caroline Keane

302
Citations
Inhibition of Natural Killer Cell Cytotoxicity by Interleukin‐6: Implications for the Pathogenesis of Macrophage Activation Syndrome

Loredana Cifaldi;Giusi Prencipe;Ivan Caiello;Claudia Bracaglia

271
Citations
Mutations in the perforin gene can be linked to macrophage activation syndrome in patients with systemic onset juvenile idiopathic arthritis

Sebastiaan J. Vastert;Richard van Wijk;Leila E. D’Urbano;Karen M. K. de Vooght

254
Citations
An International registry on Autoinflammatory diseases: the Eurofever experience

Natasa Toplak;Joost Frenkel;Seza Ozen;Helen J Lachmann

238
Citations
Functional and prognostic relevance of the -173 polymorphism of the macrophage migration inhibitory factor gene in systemic-onset juvenile idiopathic arthritis.

Fabrizio De Benedetti;Cristina Meazza;Marina Vivarelli;Federica Rossi

237
Citations
A novel disorder involving dyshematopoiesis, inflammation, and HLH due to aberrant CDC42 function.

Michael T Lam;Michael T Lam;Simona Coppola;Oliver H F Krumbach;Giusi Prencipe

196
Citations

Frequent Co-Authors

Angelo Ravelli University of Genoa

Alberto Martini University of Genoa

Nicolino Ruperto Istituto Giannina Gaslini

Daniel J. Lovell Cincinnati Children's Hospital Medical Center

Marco Gattorno Istituto Giannina Gaslini

Michael B. Jordan Cincinnati Children's Hospital Medical Center

Angela Pistorio Istituto Giannina Gaslini

Nico M Wulffraat Utrecht University

Seza Ozen Hacettepe University

Rolando Cimaz University of Milan

External Links

Personal website of Fabrizio De Benedetti

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