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Molecular Biology

D-Index
61
Citations
12392
World Ranking
1911
National Ranking
948

Overview

Eileen T. O'Toole is affiliated with the University of Colorado Boulder in the United States. Their research primarily focuses on Biochemistry, Genetics, and Molecular Biology, with notable contributions across several subfields including Molecular Biology, Cell Biology, Plant Science, Genetics, and Pediatrics, Perinatology, and Child Health.

The scientist's work addresses diverse topics, including:

  • Microtubule and mitosis dynamics
  • Genetic and kidney cyst diseases
  • Chromosomal and genetic variations
  • Fetal and pediatric neurological disorders
  • Genomics and chromatin dynamics
  • Plant nutrient uptake and metabolism
  • Cellular transport and secretion

O'Toole has published extensively, with a significant number of their articles appearing in venues such as UNC Libraries, bioRxiv (Cold Spring Harbor Laboratory), Molecular Biology of the Cell, Current Biology, and Nature Communications. Their recurrent publication venues indicate active engagement with both preprint and peer-reviewed platforms.

Frequent collaborators include Chad G. Pearson, Garry Morgan, Alexander J. Stemm-Wolf, Mark Winey, and Nalini R. Rao, pointing to collaborative research efforts in their field.

Significant recent papers authored or co-authored by O'Toole include:

  • "Mechanisms of microtubule dynamics and force generation examined with computational modeling and electron cryotomography," 2020, Nature Communications
  • "Pulse-Chase Proteomics of the App Knockin Mouse Models of Alzheimer's Disease Reveals that Synaptic Dysfunction Originates in Presynaptic Terminals," 2020, Cell Systems
  • "Comprehensive Chromosome End Remodeling during Programmed DNA Elimination," 2020, Current Biology
  • "Beat-by-Beat Cardiomyocyte T-Tubule Deformation Drives Tubular Content Exchange," 2020, Circulation Research
  • "Basal bodies bend in response to ciliary forces," 2022, Molecular Biology of the Cell

Best Publications

  • Three-dimensional ultrastructural analysis of the Saccharomyces cerevisiae mitotic spindle.

    M Winey;C L Mamay;E T O'Toole;D N Mastronarde

  • A Selective Activity-Dependent Requirement for Dynamin 1 in Synaptic Vesicle Endocytosis

    Shawn M. Ferguson;Gabor Brasnjo;Mitsuko Hayashi;Markus Wölfel

  • Piecemeal Microautophagy of Nucleus in Saccharomyces cerevisiae

    Paul Roberts;Sharon Moshitch-Moshkovitz;Erik Kvam;Eileen O'Toole

  • Centriole assembly in Caenorhabditis elegans

    Laurence Pelletier;Eileen O'Toole;Anne Schwager;Anthony A Hyman

  • Ktu/PF13 is required for cytoplasmic pre-assembly of axonemal dyneins

    Heymut Omran;Daisuke Kobayashi;Daisuke Kobayashi;Heike Olbrich;Tatsuya Tsukahara

  • Genome-wide genetic analysis of polyploidy in yeast

    Zuzana Storchová;Amanda Breneman;Jessica Cande;Joshua Dunn

  • Recruitment of Endophilin to Clathrin-Coated Pit Necks Is Required for Efficient Vesicle Uncoating after Fission

    Ira Milosevic;Silvia Giovedi;Xuelin Lou;Andrea Raimondi

  • Yeast Bim1p promotes the G1-specific dynamics of microtubules.

    Jennifer S. Tirnauer;Eileen O'Toole;Lisbeth Berrueta;Barbara E. Bierer

  • High-voltage electron tomography of spindle pole bodies and early mitotic spindles in the yeast Saccharomyces cerevisiae.

    Eileen T. O’Toole;Mark Winey;J. Richard McIntosh

  • Kinetochore microtubules in PTK cells.

    K L McDonald;E T O'Toole;D N Mastronarde;J R McIntosh

  • β-Catenin is a Nek2 substrate involved in centrosome separation

    Shirin Bahmanyar;Daniel D. Kaplan;Daniel D. Kaplan;Jennifer G. DeLuca;Jennifer G. DeLuca;Thomas H. Giddings

  • Overlapping Role of Dynamin Isoforms in Synaptic Vesicle Endocytosis

    Andrea Raimondi;Shawn M. Ferguson;Xuelin Lou;Moritz Armbruster;Moritz Armbruster

  • Conventional transmission electron microscopy

    Mark Winey;Janet B. Meehl;Eileen T. O'Toole;Thomas H. Giddings

  • Zebrafish Ciliopathy Screen Plus Human Mutational Analysis Identifies C21orf59 and CCDC65 Defects as Causing Primary Ciliary Dyskinesia

    Christina Austin-Tse;Jan Halbritter;Maimoona B Zariwala;Renée M. Gilberti

  • Electrotonic coupling of excitable and nonexcitable cells in the heart revealed by optogenetics.

    TA Quinn;P Camelliti;EA Rog-Zielinska;U Siedlecka

  • Morphologically distinct microtubule ends in the mitotic centrosome of Caenorhabditis elegans

    Eileen T. O'Toole;Kent L. McDonald;Jana Mäntler;J. Richard McIntosh

  • Chromosome congression by Kinesin-5 motor-mediated disassembly of longer kinetochore microtubules.

    Melissa K. Gardner;David C. Bouck;Leocadia V. Paliulis;Janet B. Meehl

  • Organization of Interphase Microtubules in Fission Yeast Analyzed by Electron Tomography

    Johanna L. Höög;Cindi Schwartz;Angela T. Noon;Eileen T. O'Toole

  • Components of a "dynein regulatory complex" are located at the junction between the radial spokes and the dynein arms in Chlamydomonas flagella.

    Lynne C. Gardner;Eileen O'Toole;Catherine A. Perrone;Thomas Giddings

  • Katanin Disrupts the Microtubule Lattice and Increases Polymer Number in C. elegans Meiosis

    Martin Srayko;Eileen T. O'Toole;Anthony A. Hyman;Thomas Müller-Reichert

Frequent Co-Authors

Mark Winey
Mark Winey University of California, Davis
J. Richard McIntosh
J. Richard McIntosh University of Colorado Boulder
Thomas H. Giddings
Thomas H. Giddings University of Colorado Boulder
Mary E. Porter
Mary E. Porter University of Minnesota
Kent L. McDonald
Kent L. McDonald University of California, Berkeley
Anthony A. Hyman
Anthony A. Hyman Max Planck Institute of Molecular Cell Biology and Genetics
Pietro De Camilli
Pietro De Camilli Yale University
Susan K. Dutcher
Susan K. Dutcher Washington University in St. Louis
Keith Gull
Keith Gull University of Oxford
Edward D. Salmon
Edward D. Salmon University of North Carolina at Chapel Hill

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