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Immunology

D-Index
65
Citations
12874
World Ranking
2870
National Ranking
258

Overview

David I. Pritchard is affiliated with the University of Nottingham in the United Kingdom. Their research primarily spans fields including Medicine, Immunology and Microbiology, and Environmental Science, with specific subfields covering Parasitology, Ecology, Pathology and Forensic Medicine, Immunology and Allergy, and Physiology.

The scientist's work focuses on topics related to parasites and host interactions, parasitic infections in humans and animals, allergic rhinitis and sensitization, asthma and respiratory diseases, dermatology and skin diseases, and research on leishmaniasis studies.

Notable recent publications include:

  • Hookworm Treatment for Relapsing Multiple Sclerosis (2020), published in JAMA Neurology
  • The evolution of IgE-mediated type I hypersensitivity and its immunological value (2020), published in Allergy
  • Controlled Infection of Humans with the Hookworm Parasite Necator americanus to Accelerate Vaccine Development (2021), published in Current topics in microbiology and immunology
  • An Absence of Epstein-Barr Virus Reactivation and Associations with Disease Activity in People with Multiple Sclerosis Undergoing Therapeutic Hookworm Vaccination (2020), published in Vaccines
  • Manufacture of Necator americanus as an infectious challenge agent: Accelerating human hookworm vaccine development (2025), published in Microbial Pathogenesis

Frequent co-authors include:

  • Radu Tănăsescu
  • Cris S. Constantinescu
  • Bruno Gran
  • David Diemert
  • John M. Hawdon

Their publications appear regularly in venues such as JAMA Neurology, Allergy, Current topics in microbiology and immunology, Vaccines, and Microbial Pathogenesis.

Best Publications

  • The Pseudomonas aeruginosa Quorum-Sensing Signal Molecule N-(3-Oxododecanoyl)-l-Homoserine Lactone Has Immunomodulatory Activity

    Gary Telford;D. Wheeler;Paul Williams;P. T. Tomkins

  • Independent effects of intestinal parasite infection and domestic allergen exposure on risk of wheeze in Ethiopia: a nested case-control study.

    Sarah Scrivener;Haile Yemaneberhan;Mehila Zebenigus;Daniel Tilahun

  • Asthma and current intestinal parasite infection: systematic review and meta-analysis.

    Jo Leonardi-Bee;David Pritchard;John Britton

  • A major house dust mite allergen disrupts the immunoglobulin E network by selectively cleaving CD23: innate protection by antiproteases

    Colin R. Hewitt;Alan R. Brown;Barbara J. Hart;David I. Pritchard

  • Synthetic analogues of the bacterial signal (quorum sensing) molecule N-(3-oxododecanoyl)-L-homoserine lactone as immune modulators.

    Siri Ram Chhabra;Chris Harty;Doreen S. W. Hooi;Mavis Daykin

  • A proof of concept study establishing Necator americanus in Crohn’s patients and reservoir donors

    J Croese;J O'neil;J Masson;S Cooke

  • Differential Immune Modulatory Activity of Pseudomonas aeruginosa Quorum-Sensing Signal Molecules

    Doreen S. W. Hooi;Barrie W. Bycroft;Siri Ram Chhabra;Paul Williams

  • Experimental hookworm infection: a randomized placebo-controlled trial in asthma

    J R Feary;A J Venn;K Mortimer;A P Brown

  • Basophils express a type 2 cytokine profile on exposure to proteases from helminths and house dust mites

    Clair Phillips;William R. Coward;David I. Pritchard;Colin R. A. Hewitt

  • Eotaxin is specifically cleaved by hookworm metalloproteases preventing its action in vitro and in vivo.

    Fiona J. Culley;Alan Brown;Dolores M. Conroy;Ian Sabroe

  • Bacterial N-acylhomoserine lactone-induced apoptosis in breast carcinoma cells correlated with down-modulation of STAT3.

    Li Li;Doreen Hooi;Siri Ram Chhabra;David Pritchard

  • Poor sanitation and helminth infection protect against skin sensitization in Vietnamese children: A cross-sectional study

    C Flohr;L N Tuyen;S Lewis;R Quinnell

  • Parasitic helminth glutathione S-transferases: an update on their potential as targets for immuno- and chemotherapy.

    P.M. Brophy;D.I. Pritchard

  • Cleavage of hemoglobin by hookworm cathepsin D aspartic proteases and its potential contribution to host specificity

    Angela L. Williamson;Angela L. Williamson;Paul J. Brindley;Giovanni Abbenante;Paul Prociv

  • Epidemiology and immunology of Necator americanus infection in a community in Papua New Guinea: humoral responses to excretory-secretory and cuticular collagen antigens.

    David Idris Pritchard;R. J. Quinnell;A. F. Slater;Paul G. McKean

  • Reduced helminth burden increases allergen skin sensitization but not clinical allergy: a randomized, double-blind, placebo-controlled trial in Vietnam

    Carsten Flohr;L. N. Tuyen;R. J. Quinnell;S. Lewis

  • DOSE-RANGING STUDY FOR TRIALS OF THERAPEUTIC INFECTION WITH NECATOR AMERICANUS IN HUMANS

    Kevin Mortimer;Alan Brown;Johanna Feary;Chris Jagger

  • Immunity in humans to Necator americanus‐. IgE, parasite weight and fecundity

    D. I. Pritchard;R. J. Quinnell;E. A. Walsh

  • Maggots and wound healing: an investigation of the effects of secretions from Lucilia sericata larvae upon interactions between human dermal fibroblasts and extracellular matrix components.

    A.J. Horobin;K.M. Shakesheff;S. Woodrow;C. Robinson

  • A survey of genes expressed in adults of the human hookworm, Necator americanus

    J. Daub;A. Loukas;D. I. Pritchard;M. Blaxter

  • Immune Responses in Human Necatoriasis: Association between Interleukin-5 Responses and Resistance to Reinfection

    Rupert J. Quinnell;David I. Pritchard;Andrew Raiko;Alan P. Brown

Frequent Co-Authors

Rupert J. Quinnell
Rupert J. Quinnell University of Leeds
Jerzy M. Behnke
Jerzy M. Behnke University of Nottingham
Paul Williams
Paul Williams University of Nottingham
John Britton
John Britton University of Nottingham
Barrie W. Bycroft
Barrie W. Bycroft University of Nottingham
Alex Loukas
Alex Loukas James Cook University
Siri Ram Chhabra
Siri Ram Chhabra University of Nottingham
Peter J. Hotez
Peter J. Hotez Baylor College of Medicine
Gerhard A. Schad
Gerhard A. Schad University of Pennsylvania
Colin Berry
Colin Berry University of Glasgow

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