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Medicine

D-Index
102
Citations
39728
World Ranking
7636
National Ranking
3977

Research.com Recognitions

  • 2011 - Fellow of the Indian National Academy of Engineering (INAE)

Overview

Cecilia M. Giachelli is affiliated with the University of Washington in the United States. Their research primarily spans the fields of Medicine and Biochemistry, Genetics and Molecular Biology, with significant contributions in Molecular Biology, Genetics, Cardiology and Cardiovascular Medicine, Nephrology, and Rheumatology.

The main topics covered in their work include:

  • Parathyroid Disorders and Treatments
  • Cardiac Valve Diseases and Treatments
  • Aortic Disease and Treatment Approaches
  • Genetic Syndromes and Imprinting
  • Bone Health and Treatments
  • Mesenchymal Stem Cell Research
  • Pluripotent Stem Cells Research

Giachelli has published extensively, with notable recent papers such as:

  • "Role of Runx2 in Calcific Aortic Valve Disease in Mouse Models," 2021, Frontiers in Cardiovascular Medicine
  • "Slc20a1/Pit1 and Slc20a2/Pit2 are essential for normal skeletal myofiber function and survival," 2020, Scientific Reports
  • "Engineered osteoclasts resorb necrotic alveolar bone in anti-RANKL antibody-treated mice," 2021, Bone
  • "Dissecting specific Wnt components governing osteogenic differentiation potential by human periodontal ligament stem cells through interleukin-6," 2023, Scientific Reports
  • "Grand Challenges at the Interface of Engineering and Medicine," 2024, IEEE Open Journal of Engineering in Medicine and Biology

The scientist has frequently published in venues such as Frontiers in Cardiovascular Medicine, Scientific Reports, Atherosclerosis, Bone, and the IEEE Open Journal of Engineering in Medicine and Biology.

Collaborative research is a significant component of their work, with frequent co-authors including:

  • Marta Scatena
  • Medania Purwaningrum
  • Alexander Blümke
  • Elizabeth Leber
  • Subramanian Dharmarajan

Among their professional recognitions, Cecilia M. Giachelli was elected as a Fellow of the Indian National Academy of Engineering (INAE) in 2011.

Best Publications

  • Phosphate regulation of vascular smooth muscle cell calcification.

    Shuichi Jono;Marc D. McKee;Charles E. Murry;Atsushi Shioi

  • Arterial Calcification in Chronic Kidney Disease: Key Roles for Calcium and Phosphate

    Catherine M. Shanahan;Matthew H. Crouthamel;Alexander Kapustin;Cecilia M. Giachelli

  • Smooth Muscle Cell Phenotypic Transition Associated With Calcification Upregulation of Cbfa1 and Downregulation of Smooth Muscle Lineage Markers

    Susie A. Steitz;Mei Y. Speer;Gabrielle Curinga;Hsueh Ying Yang

  • Osteopontin is elevated during neointima formation in rat arteries and is a novel component of human atherosclerotic plaques

    Cecilia M. Giachelli;Nancy Bae;Manuela Almeida;David T. Denhardt

  • Role of smooth muscle cells in vascular calcification: implications in atherosclerosis and arterial stiffness.

    Andrew L Durham;Mei Y Speer;Marta Scatena;Cecilia M Giachelli

  • Osteopontin. A Multifunctional Molecule Regulating Chronic Inflammation and Vascular Disease

    Marta Scatena;Lucy Liaw;Cecilia M. Giachelli

  • Vascular Calcification Mechanisms

    Cecilia M. Giachelli

  • Osteopontin: a versatile regulator of inflammation and biomineralization.

    Cecilia M Giachelli;Susan Steitz

  • NF-κB Mediates αvβ3 Integrin-induced Endothelial Cell Survival

    Marta Scatena;Manuela Almeida;Michelle L. Chaisson;Nelson Fausto

  • The adhesive and migratory effects of osteopontin are mediated via distinct cell surface integrins. Role of alpha v beta 3 in smooth muscle cell migration to osteopontin in vitro.

    Lucy Liaw;Michael P. Skinner;Elaine W. Raines;Russell Ross

  • Smooth Muscle Cells Give Rise to Osteochondrogenic Precursors and Chondrocytes in Calcifying Arteries

    Mei Y. Speer;Hsueh Ying Yang;Thea Brabb;Elizabeth Leaf

  • Calcification of Vascular Smooth Muscle Cell Cultures Inhibition by Osteopontin

    Takeo Wada;Marc D. McKee;Susie Steitz;Cecilia M. Giachelli

  • The role of osteopontin in inflammatory processes

    Susan Amanda Lund;Cecilia M. Giachelli;Marta Scatena

  • The emerging role of phosphate in vascular calcification

    Cecilia M. Giachelli

  • Osteopontin Is Expressed in Human Aortic Valvular Lesions

    Kevin D. O’Brien;Johanna Kuusisto;Dennis D. Reichenbach;Marina Ferguson

  • Osteopontin inhibits mineral deposition and promotes regression of ectopic calcification.

    Susan A. Steitz;Mei Y. Speer;Marc D. McKee;Lucy Liaw

  • Role of the Sodium-Dependent Phosphate Cotransporter, Pit-1, in Vascular Smooth Muscle Cell Calcification

    Xianwu Li;Hsueh Ying Yang;Cecilia M. Giachelli

  • Vascular calcification in chronic kidney disease.

    William G Goodman;Gerard London;Kerstin Amann;Geoffrey A Block

  • Osteoprotegerin Is an αvβ3-induced, NF-κB-dependent Survival Factor for Endothelial Cells

    Uriel M. Malyankar;Marta Scatena;Katherine L. Suchland;Theodore J. Yun

  • Osteopontin promotes vascular cell adhesion and spreading and is chemotactic for smooth muscle cells in vitro.

    Lucy Liaw;Manuela Almeida;Charles E. Hart;Stephen M. Schwartz

Frequent Co-Authors

Stephen M. Schwartz
Stephen M. Schwartz University of Washington
Buddy D. Ratner
Buddy D. Ratner University of Washington
Richard J. Johnson
Richard J. Johnson University of Colorado Denver
Charles E. Alpers
Charles E. Alpers University of Washington
Marc D. McKee
Marc D. McKee McGill University
Charles E. Murry
Charles E. Murry University of Washington
Elaine W. Raines
Elaine W. Raines University of Washington
William G. Couser
William G. Couser University of Washington
Lucy Liaw
Lucy Liaw Maine Medical Center
Patrick S. Stayton
Patrick S. Stayton University of Washington

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