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Carla E. M. Hollak

Carla E. M. Hollak

D-Index & Metrics

Medicine

D-Index
84
Citations
20215
World Ranking
15311
National Ranking
586

Carla E. M. Hollak publication distribution in Medicine in 2026

The chart shows the distribution of publications by all Research.com ranked scientists in the field of Medicine in 2026. The highlighted bar marks where Carla E. M. Hollak sits on this spectrum.

101–120 publications: 5 scientists 121–140 publications: 26 scientists 141–160 publications: 73 scientists 161–180 publications: 155 scientists 181–200 publications: 230 scientists 201–220 publications: 363 scientists 221–240 publications: 487 scientists 241–260 publications: 545 scientists 261–280 publications: 722 scientists 281–300 publications: 768 scientists 301–320 publications: 834 scientists 321–340 publications: 895 scientists 341–360 publications: 922 scientists 361–380 publications: 838 scientists 381–400 publications: 861 scientists 401–420 publications: 918 scientists 421–440 publications: 806 scientists 441–460 publications: 771 scientists 461–480 publications: 751 scientists 481–500 publications: 713 scientists 501–520 publications: 617 scientists 521–540 publications: 610 scientists 541–560 publications: 537 scientists 561–580 publications: 504 scientists 581–600 publications: 509 scientists 601–620 publications: 396 scientists 621–640 publications: 386 scientists 641–660 publications: 371 scientists 661–680 publications: 340 scientists 681–700 publications: 336 scientists 701–720 publications: 307 scientists 721–740 publications: 259 scientists 741–760 publications: 230 scientists 761–780 publications: 228 scientists 781–800 publications: 217 scientists 801–820 publications: 204 scientists 821–840 publications: 186 scientists 841–860 publications: 177 scientists 861–880 publications: 155 scientists 881–900 publications: 139 scientists 901–920 publications: 145 scientists 921–940 publications: 116 scientists 941–960 publications: 133 scientists 961–980 publications: 91 scientists 981–1,000 publications: 96 scientists 1,001–1,020 publications: 77 scientists 1,021–1,040 publications: 70 scientists 1,041–1,060 publications: 63 scientists 1,061–1,080 publications: 77 scientists 1,081–1,100 publications: 49 scientists 1,101–1,120 publications: 54 scientists 1,121–1,140 publications: 49 scientists 1,141–1,160 publications: 51 scientists 1,161–1,180 publications: 35 scientists 1,181–1,200 publications: 39 scientists 1,201–1,220 publications: 26 scientists 1,221–1,240 publications: 37 scientists 1,241–1,260 publications: 36 scientists 1,261–1,280 publications: 27 scientists 1,281–1,300 publications: 32 scientists 1,301–1,320 publications: 28 scientists 1,321–1,340 publications: 17 scientists 1,341–1,360 publications: 30 scientists 1,361–1,380 publications: 28 scientists 1,381–1,400 publications: 17 scientists 1,401–1,420 publications: 21 scientists 1,421–1,440 publications: 15 scientists 1,441–1,460 publications: 12 scientists 1,461–1,480 publications: 12 scientists 1,481–1,500 publications: 18 scientists 1,501–1,520 publications: 14 scientists 1,521–1,540 publications: 17 scientists 1,541–1,560 publications: 15 scientists 1,561–1,580 publications: 6 scientists 1,581–1,600 publications: 2 scientists 1,601–1,620 publications: 12 scientists 1,621–1,640 publications: 11 scientists 1,641–1,660 publications: 8 scientists 1,661–1,680 publications: 5 scientists 1,681–1,700 publications: 5 scientists 1,701–1,720 publications: 10 scientists 1,721–1,740 publications: 12 scientists 1,741–1,760 publications: 14 scientists 1,761–1,780 publications: 6 scientists 1,781–1,795 publications: 5 scientists 1,796+ publications: 100 scientists
101 publications 1,796+

This scientist: 303 publications — 17th percentile

17% of scientists in this discipline score the same or lower.

The last bar groups every scientist with 1,796 publications or more.

Carla E. M. Hollak D-index placement in Medicine in 2026

The chart shows the D-index (discipline H-index) distribution of Medicine scientists ranked by Research.com in 2026. The highlighted bar marks where Carla E. M. Hollak sits on this spectrum.

70–71 D-Index: 226 scientists 72–73 D-Index: 391 scientists 74–75 D-Index: 574 scientists 76–77 D-Index: 730 scientists 78–79 D-Index: 891 scientists 80–81 D-Index: 972 scientists 82–83 D-Index: 1,027 scientists 84–85 D-Index: 1,003 scientists 86–87 D-Index: 960 scientists 88–89 D-Index: 970 scientists 90–91 D-Index: 922 scientists 92–93 D-Index: 839 scientists 94–95 D-Index: 808 scientists 96–97 D-Index: 779 scientists 98–99 D-Index: 668 scientists 100–101 D-Index: 611 scientists 102–103 D-Index: 630 scientists 104–105 D-Index: 513 scientists 106–107 D-Index: 541 scientists 108–109 D-Index: 445 scientists 110–111 D-Index: 429 scientists 112–113 D-Index: 399 scientists 114–115 D-Index: 393 scientists 116–117 D-Index: 318 scientists 118–119 D-Index: 302 scientists 120–121 D-Index: 287 scientists 122–123 D-Index: 255 scientists 124–125 D-Index: 256 scientists 126–127 D-Index: 252 scientists 128–129 D-Index: 230 scientists 130–131 D-Index: 179 scientists 132–133 D-Index: 168 scientists 134–135 D-Index: 163 scientists 136–137 D-Index: 159 scientists 138–139 D-Index: 134 scientists 140–141 D-Index: 134 scientists 142–143 D-Index: 118 scientists 144–145 D-Index: 109 scientists 146–147 D-Index: 106 scientists 148–149 D-Index: 74 scientists 150–151 D-Index: 79 scientists 152–153 D-Index: 80 scientists 154–155 D-Index: 87 scientists 156–157 D-Index: 57 scientists 158–159 D-Index: 74 scientists 160–161 D-Index: 69 scientists 162–163 D-Index: 60 scientists 164–165 D-Index: 53 scientists 166–167 D-Index: 39 scientists 168–169 D-Index: 42 scientists 170–171 D-Index: 32 scientists 172–173 D-Index: 39 scientists 174–175 D-Index: 40 scientists 176–177 D-Index: 28 scientists 178–179 D-Index: 19 scientists 180–181 D-Index: 23 scientists 182–183 D-Index: 31 scientists 184–185 D-Index: 18 scientists 186–187 D-Index: 20 scientists 188–189 D-Index: 22 scientists 190–191 D-Index: 13 scientists 192–193 D-Index: 21 scientists 194–195 D-Index: 12 scientists 196–197 D-Index: 12 scientists 198–199 D-Index: 14 scientists 200–201 D-Index: 15 scientists 202–203 D-Index: 13 scientists 204–205 D-Index: 10 scientists 206–207 D-Index: 8 scientists 208–209 D-Index: 4 scientists 210–211 D-Index: 12 scientists 212–213 D-Index: 11 scientists 214–215 D-Index: 10 scientists 216 D-Index: 4 scientists 217+ D-Index: 98 scientists
70 D-Index 217+

This scientist: 84 D-Index — 27th percentile

27% of scientists in this discipline score the same or lower.

The last bar groups every scientist with 217 D-Index or more.

Overview

Carla E. M. Hollak is affiliated with Amsterdam UMC in the Netherlands. Their research primarily spans the fields of Medicine and Biochemistry, Genetics and Molecular Biology, with significant contributions in related subfields including Physiology, Molecular Biology, Economics and Econometrics, Clinical Biochemistry, and Organic Chemistry.

The scientist's work extensively covers topics such as Lysosomal Storage Disorders Research, Metabolism and Genetic Disorders, Pharmaceutical Economics and Policy, Health Systems, Economic Evaluations, Quality of Life, Carbohydrate Chemistry and Synthesis, Diet and Metabolism Studies, and Sphingolipid Metabolism and Signaling.

Carla E. M. Hollak has published research in several frequent venues, including:

  • Journal of Inherited Metabolic Disease
  • Orphanet Journal of Rare Diseases
  • Molecular Genetics and Metabolism
  • Value in Health
  • JIMD Reports

Selected recent publications include:

  • Developments in the treatment of Fabry disease, 2020, Journal of Inherited Metabolic Disease
  • A randomized, placebo-controlled clinical trial evaluating olipudase alfa enzyme replacement therapy for chronic acid sphingomyelinase deficiency (ASMD) in adults: One-year results, 2022, Genetics in Medicine
  • Clinical impact of the worldwide shortage of verteporfin (Visudyne®) on ophthalmic care, 2022, Acta Ophthalmologica
  • Consensus clinical management guidelines for acid sphingomyelinase deficiency (Niemann-Pick disease types A, B and A/B), 2023, Orphanet Journal of Rare Diseases
  • Predicting the Development of Anti-Drug Antibodies against Recombinant alpha-Galactosidase A in Male Patients with Classical Fabry Disease, 2020, International Journal of Molecular Sciences

Frequent collaborators in research include Mirjam Langeveld, Annet M. Bosch, Sibren van den Berg, Marion M. Brands, and André B. P. Kuilenburg.

Best Publications

  • Marked elevation of plasma chitotriosidase activity. A novel hallmark of Gaucher disease.

    C. E. M. Hollak;S. Van Weely;M. H. J. Van Oers;J. M. F. G. Aerts

  • Elevated globotriaosylsphingosine is a hallmark of Fabry disease

    Johannes M. Aerts;Johanna E. Groener;Sijmen Kuiper;Wilma E. Donker-Koopman

  • Marked elevation of the chemokine CCL18/PARC in Gaucher disease: a novel surrogate marker for assessing therapeutic intervention.

    Rolf G. Boot;Marri Verhoek;Maaike de Fost;Carla E. M. Hollak

  • Recommendations for initiation and cessation of enzyme replacement therapy in patients with Fabry disease: the European Fabry Working Group consensus document

    Marieke Biegstraaten;Reynir Arngrímsson;Frederic Barbey;Lut Boks

  • Elevated plasma glucosylsphingosine in Gaucher disease: relation to phenotype, storage cell markers, and therapeutic response

    Nick Dekker;Laura van Dussen;Carla E. M. Hollak;Herman Overkleeft

  • Characterization of Classical and Nonclassical Fabry Disease: A Multicenter Study.

    Maarten Arends;Christoph Wanner;Derralynn Hughes;Atul Mehta

  • Enzyme therapy for Fabry disease: neutralizing antibodies toward agalsidase alpha and beta.

    Gabor E. Linthorst;Carla E.M. Hollak;Wilma E. Donker-Koopman;Anneke Strijland

  • Sustained therapeutic effects of oral miglustat (Zavesca, N-butyldeoxynojirimycin, OGT 918) in type I Gaucher disease.

    D. Elstein;C. Hollak;J. M. F. G. Aerts;S. van Weely

  • The role of the iminosugar N-butyldeoxynojirimycin (miglustat) in the management of type I (non-neuronopathic) Gaucher disease: a position statement.

    T. M. Cox;J. M. F. G. Aerts;G. Andria;M. Beck

  • Plasma globotriaosylsphingosine: Diagnostic value and relation to clinical manifestations of Fabry disease

    S. M. Rombach;N. Dekker;M. G. Bouwman;G. E. Linthorst

  • Elevated plasma chitotriosidase activity in various lysosomal storage disorders.

    Yufeng Guo;Wang He;A. M. Boer;R. A. Wevers

  • Treatment of Fabry disease: outcome of a comparative trial with agalsidase alfa or beta at a dose of 0.2 mg/kg.

    Anouk C. Vedder;Gabor E. Linthorst;Gunnar Houge;Johannna E.M. Groener

  • The Dutch Fabry cohort: Diversity of clinical manifestations and Gb3 levels

    A. C. Vedder;G. E. Linthorst;M. J. van Breemen;J. E. M. Groener

  • Increased incidence of cancer in adult Gaucher disease in Western Europe.

    M. de Fost;S. vom Dahl;G.J. Weverling;N. Brill

  • Plasma and metabolic abnormalities in Gaucher's disease.

    Johannes M.F.G. Aerts;Carla E.M. Hollak

  • Elevated Levels of M-CSF, sCD14 and IL8 in Type 1 Gaucher Disease☆☆☆

    C.E.M. Hollak;L.M. Evers;J.M.F.G. Aerts;M.H.J. van Oers

  • Screening for Fabry disease in high-risk populations: a systematic review

    Gabor E Linthorst;Machtelt G Bouwman;Frits A Wijburg;Johannes Mfg Aerts

  • Superior effects of high-dose enzyme replacement therapy in type 1 Gaucher disease on bone marrow involvement and chitotriosidase levels: a 2-center retrospective analysis

    Maaike de Fost;Carla E M Hollak;Johanna E M Groener;Johannes M F G Aerts

  • Quantification of bone involvement in Gaucher disease: MR imaging bone marrow burden score as an alternative to Dixon quantitative chemical shift MR imaging--initial experience

    Mario Maas;Cornelis van Kuijk;Jaap Stoker;Carla E M Hollak

  • Treatment of Fabry disease with different dosing regimens of agalsidase: effects on antibody formation and GL-3.

    Anouk C. Vedder;Frank Breunig;Wilma E. Donker-Koopman;Kevin Mills

Frequent Co-Authors

Johannes M. F. G. Aerts
Johannes M. F. G. Aerts Leiden University
Marcel G. W. Dijkgraaf
Marcel G. W. Dijkgraaf University of Amsterdam
Herman S. Overkleeft
Herman S. Overkleeft Leiden University
Jaap Stoker
Jaap Stoker University of Amsterdam
Maria Domenica Cappellini
Maria Domenica Cappellini University of Milan
Frits A. Wijburg
Frits A. Wijburg University of Amsterdam
Peter L.M. Jansen
Peter L.M. Jansen Maastricht University
Paul Lips
Paul Lips Vrije Universiteit Amsterdam
Rolf G. Boot
Rolf G. Boot Leiden University
Timothy M. Cox
Timothy M. Cox University of Cambridge

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