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D-Index & Metrics

Biology and Biochemistry

D-Index
54
Citations
8815
World Ranking
15784
National Ranking
1237

Angela Pyle publication distribution in Biology and Biochemistry in 2026

The chart shows the distribution of publications by all Research.com ranked scientists in the field of Biology and Biochemistry in 2026. The highlighted bar marks where Angela Pyle sits on this spectrum.

47–56 publications: 8 scientists 57–66 publications: 35 scientists 67–76 publications: 106 scientists 77–86 publications: 231 scientists 87–96 publications: 414 scientists 97–106 publications: 546 scientists 107–116 publications: 704 scientists 117–126 publications: 849 scientists 127–136 publications: 980 scientists 137–146 publications: 942 scientists 147–156 publications: 969 scientists 157–166 publications: 950 scientists 167–176 publications: 951 scientists 177–186 publications: 915 scientists 187–196 publications: 787 scientists 197–206 publications: 841 scientists 207–216 publications: 735 scientists 217–226 publications: 709 scientists 227–236 publications: 651 scientists 237–246 publications: 605 scientists 247–256 publications: 510 scientists 257–266 publications: 524 scientists 267–276 publications: 434 scientists 277–286 publications: 418 scientists 287–296 publications: 350 scientists 297–306 publications: 363 scientists 307–316 publications: 315 scientists 317–326 publications: 296 scientists 327–336 publications: 261 scientists 337–346 publications: 240 scientists 347–356 publications: 219 scientists 357–366 publications: 197 scientists 367–376 publications: 154 scientists 377–386 publications: 161 scientists 387–396 publications: 155 scientists 397–406 publications: 145 scientists 407–416 publications: 124 scientists 417–426 publications: 112 scientists 427–436 publications: 132 scientists 437–446 publications: 116 scientists 447–456 publications: 99 scientists 457–466 publications: 81 scientists 467–476 publications: 91 scientists 477–486 publications: 80 scientists 487–496 publications: 80 scientists 497–506 publications: 60 scientists 507–516 publications: 36 scientists 517–526 publications: 46 scientists 527–536 publications: 54 scientists 537–546 publications: 44 scientists 547–556 publications: 43 scientists 557–566 publications: 43 scientists 567–576 publications: 42 scientists 577–586 publications: 25 scientists 587–596 publications: 34 scientists 597–606 publications: 23 scientists 607–616 publications: 33 scientists 617–626 publications: 31 scientists 627–636 publications: 27 scientists 637–646 publications: 25 scientists 647–656 publications: 28 scientists 657–666 publications: 34 scientists 667–676 publications: 18 scientists 677–686 publications: 16 scientists 687–696 publications: 10 scientists 697–706 publications: 12 scientists 707–716 publications: 21 scientists 717–726 publications: 12 scientists 727–736 publications: 12 scientists 737–746 publications: 10 scientists 747–756 publications: 7 scientists 757–766 publications: 13 scientists 767–776 publications: 15 scientists 777–786 publications: 13 scientists 787–796 publications: 9 scientists 797–806 publications: 9 scientists 807–816 publications: 7 scientists 817–826 publications: 4 scientists 827–836 publications: 9 scientists 837–846 publications: 7 scientists 847–856 publications: 3 scientists 857–866 publications: 5 scientists 867–876 publications: 5 scientists 877–886 publications: 11 scientists 887–896 publications: 3 scientists 897–906 publications: 4 scientists 907–916 publications: 7 scientists 917–926 publications: 5 scientists 927–936 publications: 6 scientists 937–946 publications: 6 scientists 947–956 publications: 3 scientists 957–966 publications: 7 scientists 967–976 publications: 2 scientists 977–986 publications: 2 scientists 987–996 publications: 1 scientists 997–1,006 publications: 5 scientists 1,007–1,016 publications: 2 scientists 1,017–1,026 publications: 2 scientists 1,027 publications: 1 scientists 1,028+ publications: 100 scientists
47 publications 1,028+

This scientist: 158 publications — 30th percentile

30% of scientists in this discipline score the same or lower.

The last bar groups every scientist with 1,028 publications or more.

Angela Pyle D-index placement in Biology and Biochemistry in 2026

The chart shows the D-index (discipline H-index) distribution of Biology and Biochemistry scientists ranked by Research.com in 2026. The highlighted bar marks where Angela Pyle sits on this spectrum.

40–41 D-Index: 80 scientists 42–43 D-Index: 183 scientists 44–45 D-Index: 317 scientists 46–47 D-Index: 504 scientists 48–49 D-Index: 718 scientists 50–51 D-Index: 900 scientists 52–53 D-Index: 1,026 scientists 54–55 D-Index: 1,150 scientists 56–57 D-Index: 1,236 scientists 58–59 D-Index: 1,253 scientists 60–61 D-Index: 1,163 scientists 62–63 D-Index: 1,131 scientists 64–65 D-Index: 1,032 scientists 66–67 D-Index: 897 scientists 68–69 D-Index: 814 scientists 70–71 D-Index: 715 scientists 72–73 D-Index: 709 scientists 74–75 D-Index: 596 scientists 76–77 D-Index: 512 scientists 78–79 D-Index: 473 scientists 80–81 D-Index: 412 scientists 82–83 D-Index: 373 scientists 84–85 D-Index: 358 scientists 86–87 D-Index: 285 scientists 88–89 D-Index: 273 scientists 90–91 D-Index: 227 scientists 92–93 D-Index: 208 scientists 94–95 D-Index: 193 scientists 96–97 D-Index: 153 scientists 98–99 D-Index: 157 scientists 100–101 D-Index: 148 scientists 102–103 D-Index: 120 scientists 104–105 D-Index: 113 scientists 106–107 D-Index: 100 scientists 108–109 D-Index: 86 scientists 110–111 D-Index: 67 scientists 112–113 D-Index: 72 scientists 114–115 D-Index: 73 scientists 116–117 D-Index: 64 scientists 118–119 D-Index: 53 scientists 120–121 D-Index: 60 scientists 122–123 D-Index: 54 scientists 124–125 D-Index: 43 scientists 126–127 D-Index: 38 scientists 128–129 D-Index: 49 scientists 130–131 D-Index: 26 scientists 132–133 D-Index: 18 scientists 134–135 D-Index: 23 scientists 136–137 D-Index: 32 scientists 138–139 D-Index: 32 scientists 140–141 D-Index: 27 scientists 142–143 D-Index: 19 scientists 144–145 D-Index: 22 scientists 146–147 D-Index: 12 scientists 148–149 D-Index: 16 scientists 150–151 D-Index: 14 scientists 152–153 D-Index: 10 scientists 154–155 D-Index: 13 scientists 156–157 D-Index: 10 scientists 158–159 D-Index: 7 scientists 160–161 D-Index: 9 scientists 162–163 D-Index: 13 scientists 164–165 D-Index: 4 scientists 166 D-Index: 4 scientists 167+ D-Index: 98 scientists
40 D-Index 167+

This scientist: 54 D-Index — 22nd percentile

22% of scientists in this discipline score the same or lower.

The last bar groups every scientist with 167 D-Index or more.

Overview

Angela Pyle is affiliated with Newcastle University in the United Kingdom and has contributed extensively to the field of Biochemistry, Genetics, and Molecular Biology. Their research spans multiple subfields including Molecular Biology, Clinical Biochemistry, Neurology, Genetics, and Cancer Research.

The scientist's work focuses primarily on key topics such as mitochondrial function and pathology, metabolism and genetic disorders, RNA modifications and cancer, neurological diseases and metabolism, Parkinson's disease mechanisms and treatments, genetic neurodegenerative diseases, and metabolomics and mass spectrometry studies.

Recent publications demonstrate a focus on mitochondrial biology and metabolic effects in disease contexts. Notable papers include:

  • Age-associated mitochondrial DNA mutations cause metabolic remodeling that contributes to accelerated intestinal tumorigenesis (2020, Nature Cancer)
  • Defining mitochondrial protein functions through deep multiomic profiling (2022, Nature)
  • Circulating cell-free mitochondrial DNA levels in Parkinson's disease are influenced by treatment (2020, Molecular Neurodegeneration)
  • Metabolic effects of bezafibrate in mitochondrial disease (2020, EMBO Molecular Medicine)
  • Metabolic shift underlies recovery in reversible infantile respiratory chain deficiency (2020, The EMBO Journal)

Frequent coauthors collaborating with Angela Pyle include Gavin Hudson, Robert W. Taylor, Patrick F. Chinnery, Dasha Deen, and Fiona Robertson.

Publication activity is concentrated in venues such as bioRxiv (Cold Spring Harbor Laboratory), Scientific Reports, Nature Cancer, Methods in Molecular Biology, and Research Square (Research Square).

Best Publications

  • Clinical Expression of Leber Hereditary Optic Neuropathy Is Affected by the Mitochondrial DNA–Haplogroup Background

    Gavin Hudson;Valerio Carelli;Valerio Carelli;Liesbeth Spruijt;Mike Gerards

  • Use of Whole-Exome Sequencing to Determine the Genetic Basis of Multiple Mitochondrial Respiratory Chain Complex Deficiencies

    Robert W. Taylor;Angela Pyle;Helen Griffin;Emma L. Blakely

  • Whole-genome sequencing of patients with rare diseases in a national health system

    Ernest Turro;William J Astle;Karyn Megy;Stefan Graf

  • Efficient mitochondrial biogenesis drives incomplete penetrance in Leber's hereditary optic neuropathy.

    Carla Giordano;Luisa Iommarini;Luca Giordano;Alessandra Maresca

  • Whole-genome sequencing of a sporadic primary immunodeficiency cohort

    Thaventhiran Jed.;H Lango Allen;O S Burren;W Rae

  • Reduced mitochondrial DNA copy number is a biomarker of Parkinson's disease

    Angela Pyle;Haidyan Anugrha;Marzena Kurzawa-Akanbi;Alison Yarnall

  • Segregation of mitochondrial DNA heteroplasmy through a developmental genetic bottleneck in human embryos

    Vasileios I. Floros;Vasileios I. Floros;Angela Pyle;Sabine Dietmann;Wei Wei;Wei Wei

  • Mitochondrial DNA and survival after sepsis : a prospective study

    Simon V Baudouin;David Saunders;Watcharee Tiangyou;Joanna L Elson

  • Mutations in the SPG7 gene cause chronic progressive external ophthalmoplegia through disordered mitochondrial DNA maintenance.

    Gerald Pfeffer;Gráinne S Gorman;Helen Griffin;Marzena Kurzawa-Akanbi

  • Exome sequencing in undiagnosed inherited and sporadic ataxias

    Angela Pyle;Tania Smertenko;David Bargiela;Helen Griffin

  • Molecular basis of infantile reversible cytochrome c oxidase deficiency myopathy

    Rita Horvath;John P. Kemp;Helen A. L. Tuppen;Gavin Hudson

  • Mutations in GTPBP3 Cause a Mitochondrial Translation Defect Associated with Hypertrophic Cardiomyopathy, Lactic Acidosis, and Encephalopathy

    Robert Kopajtich;Thomas J. Nicholls;Joanna Rorbach;Metodi D. Metodiev

  • EXOSC8 mutations alter mRNA metabolism and cause hypomyelination with spinal muscular atrophy and cerebellar hypoplasia

    Veronika Boczonadi;Juliane S. Müller;Angela Pyle;Jennifer Munkley

  • Defective i6A37 Modification of Mitochondrial and Cytosolic tRNAs Results from Pathogenic Mutations in TRIT1 and Its Substrate tRNA

    John W. Yarham;Tek N. Lamichhane;Angela Pyle;Sandy Mattijssen

  • Recent advances in understanding the molecular genetic basis of mitochondrial disease.

    Kyle Thompson;Jack J. Collier;Ruth I. C. Glasgow;Fiona M. Robertson

  • Riboflavin-Responsive and -Non-responsive Mutations in FAD Synthase Cause Multiple Acyl-CoA Dehydrogenase and Combined Respiratory-Chain Deficiency

    Rikke K.J. Olsen;Eliška Koňaříková;Teresa A. Giancaspero;Signe Mosegaard

  • Reduced cerebrospinal fluid mitochondrial DNA is a biomarker for early-stage Parkinson's disease.

    Angela Pyle;Rebecca Brennan;Marzena Kurzawa-Akanbi;Alison Yarnall

  • Synaptotagmin 2 Mutations Cause an Autosomal-Dominant Form of Lambert-Eaton Myasthenic Syndrome and Nonprogressive Motor Neuropathy

    David N. Herrmann;Rita Horvath;Janet E. Sowden;Michael Gonzales

  • Hypomorphic mutations in POLR3A are a frequent cause of sporadic and recessive spastic ataxia.

    Martina Minnerop;Martina Minnerop;Delia Kurzwelly;Delia Kurzwelly;Holger Wagner;Anne S Soehn

  • Recessive Mutations in TRMT10C Cause Defects in Mitochondrial RNA Processing and Multiple Respiratory Chain Deficiencies

    Metodi D. Metodiev;Kyle Thompson;Charlotte L. Alston;Andrew A.M. Morris;Andrew A.M. Morris

Frequent Co-Authors

Patrick F. Chinnery
Patrick F. Chinnery University of Cambridge
Rita Horvath
Rita Horvath University of Cambridge
Robert W. Taylor
Robert W. Taylor Newcastle University
Gavin Hudson
Gavin Hudson Newcastle University
Hanns Lochmüller
Hanns Lochmüller University of Freiburg
Patrick Yu-Wai-Man
Patrick Yu-Wai-Man University of Cambridge
Mauro Santibanez-Koref
Mauro Santibanez-Koref Newcastle University
Robert McFarland
Robert McFarland Newcastle University
Charlotte L. Alston
Charlotte L. Alston Newcastle University
Emma L. Blakely
Emma L. Blakely Newcastle University

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