Alan Trudgett

Best Publications

• Understanding triclabendazole resistance.

  G. P. Brennan;I. Fairweather;A. Trudgett;E. Hoey

  280
  Citations

• Purification of a cathepsin L-like proteinase secreted by adult Fasciola hepatica

  Angela M. Smith;Andrew J. Dowd;Sharon McGonigle;Paul S. Keegan

  206
  Citations

• A possible model of benzimidazole binding to β-tubulin disclosed by invoking an inter-domain movement

  Mark W. Robinson;Neil McFerran;Alan Trudgett;Liz Hoey

  171
  Citations

• Triclabendazole-resistant Fasciola hepatica: β-tubulin and response to in vitro treatment with triclabendazole

  M. W. Robinson;A. Trudgett;E. M. Hoey;I. Fairweather

  155
  Citations

• The comparative metabolism of triclabendazole sulphoxide by triclabendazole-susceptible and triclabendazole-resistant Fasciola hepatica

  Mark W. Robinson;Jill Lawson;Alan Trudgett;Elizabeth M. Hoey

  151
  Citations

• The distribution of Fasciola hepatica and Fasciola gigantica within southern Tanzania - constraints associated with the intermediate host

  Stephen Walker;A.E. Makundi;F.V. Namuba;A.A. Kassuku

  100
  Citations

• Development of an egg hatch assay for the diagnosis of triclabendazole resistance in Fasciola hepatica: proof of concept.

  Ian Fairweather;D.D. McShane;L. Shaw;S.E. Ellison

  96
  Citations

• Microtubules as antiparasitic drug targets.

  B.J. Fennell;J.A. Naughton;J. Barlow;Gerard Brennan

  92
  Citations

• Relative activity of triclabendazole metabolites against the liver fluke, Fasciola hepatica

  L. Halferty;G.P. Brennan;A. Trudgett;L. Hoey

  91
  Citations

• A metagenomic comparison of endemic viruses from broiler chickens with runting-stunting syndrome and from normal birds.

  Unknown

  91
  Citations

• The occurrence and significance of triploidy in the liver fluke, Fasciola hepatica.

  H. L. Fletcher;E. M. Hoey;N. Orr;A. Trudgett

  84
  Citations

• Multiple origins of European populations of the giant liver fluke Fascioloides magna (Trematoda: Fasciolidae), a liver parasite of ruminants.

  Ivica Králová-Hromadová;Eva Bazsalovicsová;Jan Štefka;Jan Štefka;Marta Špakulová

  83
  Citations

• Fasciola hepatica: surface and internal tegumental changes induced by treatment in vitro with the sulphoxide metabolite of albendazole ('Valbazen')

  J. F. Buchanan;I. Fairweather;G. P. Brennan;A. Trudgett

  79
  Citations

• Response of two isolates of Fasciola hepatica to treatment with triclabendazole in vivo and in vitro

  Stephen Walker;B. McKinstry;J.C. Boray;Gerard Brennan

  75
  Citations

• Fasciola hepatica expresses multiple α- and β-tubulin isotypes

  Louise A. Ryan;Elizabeth Hoey;Alan Trudgett;Ian Fairweather

  74
  Citations

• Bovine paramphistomes in Ireland.

  Annetta Zintl;Andres Garcia-Campos;Alan Trudgett;Andreas L. Chryssafidis

  68
  Citations

• Population dynamics of the liver fluke, Fasciola hepatica: the effect of time and spatial separation on the genetic diversity of fluke populations in the Netherlands

  Stephen Walker;Catherine Johnston;Elizabeth Hoey;Ian Fairweather

  65
  Citations

• Evidence for multiple mitochondrial lineages of Fasciola hepatica (liver fluke) within infrapopulations from cattle and sheep.

  Unknown

  65
  Citations

• Fasciola hepatica: development of monoclonal antibodies and their use to characterize a glycocalyx antigen in migrating flukes

  Unknown

  57
  Citations

• Tegumental surface changes in juvenile Fasciola hepatica in response to treatment in vivo with triclabendazole

  L. Halferty;G.P. Brennan;R.E.B. Hanna;H.W. Edgar

  56
  Citations