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Immunology

D-Index
61
Citations
20699
World Ranking
3192
National Ranking
1495

Overview

Xavier Alvarez is affiliated with Tulane University in the United States and primarily researches in the field of Medicine, with a strong focus on Infectious Diseases, Epidemiology, and Virology. Their scholarly work encompasses molecular biology and neurology, reflecting a multidisciplinary approach within biomedical sciences.

The scientist's research topics cover several areas, notably:

  • HIV Research and Treatment
  • SARS-CoV-2 and COVID-19 Research
  • COVID-19 Clinical Research Studies
  • Tuberculosis Research and Epidemiology
  • Long-Term Effects of COVID-19
  • Tryptophan and brain disorders
  • Mycobacterium research and diagnosis

Xavier Alvarez has contributed to multiple prominent peer-reviewed journals, publishing frequently in:

  • bioRxiv (Cold Spring Harbor Laboratory)
  • JCI Insight
  • Nature Communications
  • Nature Microbiology
  • Journal of Clinical Investigation

Among their recent papers are:

  • "Lethality of SARS-CoV-2 infection in K18 human angiotensin-converting enzyme 2 transgenic mice" (2020, Nature Communications)
  • "Responses to acute infection with SARS-CoV-2 in the lungs of rhesus macaques, baboons and marmosets" (2020, Nature Microbiology)
  • "Pulmonary Mycobacterium tuberculosis control associates with CXCR3- and CCR6-expressing antigen-specific Th1 and Th17 cell recruitment" (2020, JCI Insight)
  • "Lethality of SARS-CoV-2 infection in K18 human angiotensin converting enzyme 2 transgenic mice" (2020, bioRxiv - Cold Spring Harbor Laboratory)
  • "Antiretroviral therapy does not reduce tuberculosis reactivation in a tuberculosis-HIV coinfection model" (2020, Journal of Clinical Investigation)

The scientist collaborates frequently with several researchers, including:

  • Deepak Kaushal
  • Edward J. Dick
  • Dhiraj Kumar Singh
  • Shashank Ganatra
  • Shannan Hall-Ursone

Xavier Alvarez's academic work primarily explores the interaction of infectious agents such as HIV, Mycobacterium tuberculosis, and SARS-CoV-2 with the human immune system. Studies on COVID-19 and tuberculosis underline their interest in disease pathogenesis, immune responses, and treatment outcomes in both clinical and experimental settings.

Best Publications

  • Specific recruitment of regulatory T cells in ovarian carcinoma fosters immune privilege and predicts reduced survival.

    Tyler J Curiel;George Coukos;Linhua Zou;Xavier Alvarez

  • Blockade of B7-H1 improves myeloid dendritic cell-mediated antitumor immunity.

    Tyler J Curiel;Shuang Wei;Haidong Dong;Xavier Alvarez

  • Anti–spike IgG causes severe acute lung injury by skewing macrophage responses during acute SARS-CoV infection

    Li Liu;Qiang Wei;Qingqing Lin;Jun Fang

  • B7-H4 expression identifies a novel suppressive macrophage population in human ovarian carcinoma

    Ilona Kryczek;Ilona Kryczek;Linhua Zou;Linhua Zou;Paulo Rodriguez;Gefeng Zhu

  • CXCL12 and Vascular Endothelial Growth Factor Synergistically Induce Neoangiogenesis in Human Ovarian Cancers

    Ilona Kryczek;Andrzej Lange;Peter Mottram;Xavier Alvarez

  • Epithelial Cells Lining Salivary Gland Ducts Are Early Target Cells of Severe Acute Respiratory Syndrome Coronavirus Infection in the Upper Respiratory Tracts of Rhesus Macaques

    Li Liu;Qiang Wei;Xavier Alvarez;Haibo Wang

  • Perivascular Macrophages Are the Primary Cell Type Productively Infected by Simian Immunodeficiency Virus in the Brains of Macaques: Implications for the Neuropathogenesis of AIDS

    Kenneth C. Williams;Sarah Corey;Susan V. Westmoreland;Doug Pauley

  • Lethality of SARS-CoV-2 infection in K18 human angiotensin-converting enzyme 2 transgenic mice.

    Fatai S. Oladunni;Jun-Gyu Park;Paula A. Pino;Olga Gonzalez

  • Dendritic cell subsets differentially regulate angiogenesis in human ovarian cancer

    Tyler J. Curiel;Pui Cheng;Peter Mottram;Xavier Alvarez

  • Central nervous system perivascular cells are immunoregulatory cells that connect the CNS with the peripheral immune system.

    Kenneth Williams;Xavier Alvarez;Andrew A. Lackner

  • CD163 Identifies Perivascular Macrophages in Normal and Viral Encephalitic Brains and Potential Precursors to Perivascular Macrophages in Blood

    Woong-Ki Kim;Xavier Alvarez;Jeanne Fisher;Benjamin Bronfin

  • In Vivo Characterization of Alveolar and Interstitial Lung Macrophages in Rhesus Macaques: Implications for Understanding Lung Disease in Humans

    Yanhui Cai;Chie Sugimoto;Mariluz Arainga;Xavier Alvarez

  • Increased monocyte turnover from bone marrow correlates with severity of SIV encephalitis and CD163 levels in plasma.

    Tricia H. Burdo;Caroline Soulas;Krystyna Orzechowski;Jessica Button

  • Mucosal vaccination with attenuated Mycobacterium tuberculosis induces strong central memory responses and protects against tuberculosis.

    Deepak Kaushal;Taylor W. Foreman;Uma S. Gautam;Xavier Alvarez

  • In vivo inhibition of tryptophan catabolism reorganizes the tuberculoma and augments immune-mediated control of Mycobacterium tuberculosis

    Uma S. Gautam;Taylor W. Foreman;Allison N. Bucsan;Ashley V. Veatch

  • Androgen receptor splice variants activating the full-length receptor in mediating resistance to androgen-directed therapy.

    Bo Cao;Yanfeng Qi;Guanyi Zhang;Duo Xu

  • The DosR Regulon Modulates Adaptive Immunity and Is Essential for Mycobacterium tuberculosis Persistence

    Smriti Mehra;Taylor W. Foreman;Peter J. Didier;Muhammad H. Ahsan

  • The level of monocyte turnover predicts disease progression in the macaque model of AIDS.

    Atsuhiko Hasegawa;Huining Liu;Binhua Ling;Juan T. Borda

  • Responses to acute infection with SARS-CoV-2 in the lungs of rhesus macaques, baboons and marmosets.

    Dhiraj Kumar Singh;Bindu Singh;Shashank R. Ganatra;Michal Gazi

  • Superoxide anion production in the rat penis impairs erectile function in diabetes: influence of in vivo extracellular superoxide dismutase gene therapy.

    Trinity J. Bivalacqua;Mustafa F. Usta;Muammer Kendirci;Leena Pradhan

  • Genetic Requirements for the Survival of Tubercle Bacilli in Primates

    Noton K. Dutta;Smriti Mehra;Peter J. Didier;Chad J. Roy

  • Lethality of SARS-CoV-2 infection in K18 human angiotensin converting enzyme 2 transgenic mice

    Fatai S. Oladunni;Jun-Gyu Park;Paula Pino Tamayo;Olga Gonzalez

Frequent Co-Authors

Andrew A. Lackner
Andrew A. Lackner Tulane University
Ronald S. Veazey
Ronald S. Veazey Tulane University
Deepak Kaushal
Deepak Kaushal Texas Biomedical Research Institute
Kenneth C. Williams
Kenneth C. Williams The University of Texas Health Science Center at San Antonio
Marcelo J. Kuroda
Marcelo J. Kuroda University of California, Davis
Elizabeth S. Didier
Elizabeth S. Didier Tulane University
James Blanchard
James Blanchard Tulane University
C. Roy
C. Roy Centre national de la recherche scientifique, CNRS
Weiping Zou
Weiping Zou University of Michigan–Ann Arbor
Tyler J. Curiel
Tyler J. Curiel The University of Texas at San Antonio

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