D-Index & Metrics Best Publications

D-Index & Metrics D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines.

Discipline name D-index D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines. Citations Publications World Ranking National Ranking
Neuroscience D-index 50 Citations 18,351 67 World Ranking 2314 National Ranking 1089

Overview

What is she best known for?

The fields of study she is best known for:

  • Dopamine
  • Enzyme
  • Apoptosis

Her scientific interests lie mostly in MPTP, Neurodegeneration, Substantia nigra, Dopaminergic and Dopamine. Her studies in MPTP integrate themes in fields like Neurotoxin, Biochemistry and Pharmacology. The study incorporates disciplines such as Immunology, Neuroscience and Parkinson's disease in addition to Neurodegeneration.

Her study in the field of LRRK2 is also linked to topics like Plant biology. As part of one scientific family, Vernice Jackson-Lewis deals mainly with the area of Substantia nigra, narrowing it down to issues related to the Neurotoxicity, and often Oxidative stress. Internal medicine and Endocrinology are the two main areas of interest in her Dopaminergic studies.

Her most cited work include:

  • Blockade of Microglial Activation Is Neuroprotective in the 1-Methyl-4-Phenyl-1,2,3,6-Tetrahydropyridine Mouse Model of Parkinson Disease (1054 citations)
  • Inducible nitric oxide synthase stimulates dopaminergic neurodegeneration in the MPTP model of Parkinson disease. (916 citations)
  • Functional role of caspase-1 and caspase-3 in an ALS transgenic mouse model. (625 citations)

What are the main themes of her work throughout her whole career to date?

Her primary scientific interests are in Substantia nigra, MPTP, Internal medicine, Endocrinology and Dopamine. Her Substantia nigra study is concerned with the larger field of Neuroscience. Her study in Neuroscience is interdisciplinary in nature, drawing from both Disease and Microglia.

Her MPTP research incorporates elements of Neurotoxicity, Neurotoxin, Biochemistry and Neurodegeneration. Her study in the fields of Reserpine, Dopamine agonist and Oxidopamine under the domain of Endocrinology overlaps with other disciplines such as Peroxynitrite. Her studies examine the connections between Dopamine and genetics, as well as such issues in Homovanillic acid, with regards to Mitochondrial respiratory chain.

She most often published in these fields:

  • Substantia nigra (44.04%)
  • MPTP (41.28%)
  • Internal medicine (40.37%)

What were the highlights of her more recent work (between 2010-2019)?

  • Neuroscience (33.94%)
  • Parkinson's disease (31.19%)
  • Dopaminergic (32.11%)

In recent papers she was focusing on the following fields of study:

Vernice Jackson-Lewis mainly investigates Neuroscience, Parkinson's disease, Dopaminergic, MPTP and Substantia nigra. Neuroscience is closely attributed to Neurodegeneration in her research. Her Alpha-synuclein study in the realm of Parkinson's disease connects with subjects such as Genetically modified mouse.

Vernice Jackson-Lewis interconnects Glial cell line-derived neurotrophic factor, Neurochemical and Cholinergic neuron in the investigation of issues within Dopaminergic. Her work carried out in the field of MPTP brings together such families of science as Neurotrophic factors, Etiology and Tyrosine hydroxylase. Her Substantia nigra research is multidisciplinary, incorporating perspectives in Microgliosis and Cell biology.

Between 2010 and 2019, her most popular works were:

  • Oxidative stress and Parkinson’s disease (373 citations)
  • Classic and New Animal Models of Parkinson's Disease (331 citations)
  • Neuromelanin Activates Microglia and Induces Degeneration of Dopaminergic Neurons: Implications for Progression of Parkinson’s Disease (144 citations)

In her most recent research, the most cited papers focused on:

  • Enzyme
  • Dopamine
  • Apoptosis

Her primary areas of investigation include Neuroscience, Parkinson's disease, MPTP, Disease and Cell biology. Her work in Dopaminergic and Substantia nigra are all subfields of Neuroscience research. Her biological study spans a wide range of topics, including NADPH oxidase, Neuroinflammation and Microglia.

Her MPTP Poisoning study, which is part of a larger body of work in MPTP, is frequently linked to Extramural, bridging the gap between disciplines. Her Cell biology research incorporates themes from Astrocyte, Induced pluripotent stem cell and Fibroblast growth factor. Her Neurodegeneration study combines topics from a wide range of disciplines, such as Oxidative stress, Neurotoxicity, Pars compacta, Respiratory chain and Microgliosis.

This overview was generated by a machine learning system which analysed the scientist’s body of work. If you have any feedback, you can contact us here.

Best Publications

Blockade of Microglial Activation Is Neuroprotective in the 1-Methyl-4-Phenyl-1,2,3,6-Tetrahydropyridine Mouse Model of Parkinson Disease

Du Chu Wu;Vernice Jackson-Lewis;Miquel Vila;Kim Tieu.
The Journal of Neuroscience (2002)

1360 Citations

Inducible nitric oxide synthase stimulates dopaminergic neurodegeneration in the MPTP model of Parkinson disease.

G T Liberatore;V Jackson-Lewis;S Vukosavic;A S Mandir.
Nature Medicine (1999)

1159 Citations

Protocol for the MPTP mouse model of Parkinson's disease

Vernice Jackson-Lewis;Serge Przedborski.
Nature Protocols (2007)

821 Citations

Functional role of caspase-1 and caspase-3 in an ALS transgenic mouse model.

Mingwei Li;Victor O. Ona;Christelle Guégan;Minghua Chen.
Science (2000)

806 Citations

Role of neuronal nitric oxide in 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP)-induced dopaminergic neurotoxicity.

Serge Przedborski;Vernice Jackson-Lewis;Rina Yokoyama;Toshihiro Shibata.
Proceedings of the National Academy of Sciences of the United States of America (1996)

721 Citations

Cyclooxygenase-2 is instrumental in Parkinson's disease neurodegeneration

Peter Teismann;Kim Tieu;Dong-Kug Choi;Du-Chu Wu.
Proceedings of the National Academy of Sciences of the United States of America (2003)

701 Citations

NADPH oxidase mediates oxidative stress in the 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine model of Parkinson's disease

Du-Chu Wu;Peter Teismann;Kim Tieu;Miquel Vila.
Proceedings of the National Academy of Sciences of the United States of America (2003)

669 Citations

Resistance of alpha -synuclein null mice to the parkinsonian neurotoxin MPTP.

William Dauer;Nikolai Kholodilov;Miquel Vila;Anne Cecile Trillat.
Proceedings of the National Academy of Sciences of the United States of America (2002)

644 Citations

Time course and morphology of dopaminergic neuronal death caused by the neurotoxin 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine

Vernice Jackson-Lewis;Michael Jakowec;Robert E Burke;Serge Przedborski.
Neurodegeneration (1995)

639 Citations

Oxidative stress and Parkinson’s disease

Javier Blesa;Ines Trigo-Damas;Anna Quiroga-Varela;Vernice R. Jackson-Lewis.
Frontiers in Neuroanatomy (2015)

631 Citations

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