World's Best Scientists 2026 revealed!

D-Index & Metrics

Biology and Biochemistry

D-Index
64
Citations
19315
World Ranking
9494
National Ranking
4190

Overview

Sergei V. Kotenko is affiliated with Rutgers, The State University of New Jersey in the United States. Their research focuses primarily on immunology, microbiology, and medicine, making significant contributions across these fields through numerous scientific publications.

The main fields of study for Kotenko include:

  • Immunology and Microbiology
  • Medicine

Their research involves various subfields, notably:

  • Immunology
  • Infectious Diseases
  • Epidemiology
  • Molecular Biology
  • Physiology

Thematic topics addressed in Kotenko's work include:

  • Immune Cell Function and Interaction
  • Phagocytosis and Immune Regulation
  • T-cell and B-cell Immunology
  • Erythrocyte Function and Pathophysiology
  • Interferon and Immune Responses
  • Systemic Lupus Erythematosus Research
  • Inflammasome and Immune Disorders

Kotenko's recent papers illustrate their engagement with contemporary issues in immunology and disease. Selected works include:

  • COVID-19 and emerging viral infections: The case for interferon lambda, 2020, The Journal of Experimental Medicine
  • Interferon lambda promotes immune dysregulation and tissue inflammation in TLR7-induced lupus, 2020, Proceedings of the National Academy of Sciences
  • Axl and Mertk Receptors Cooperate to Promote Breast Cancer Progression by Combined Oncogenic Signaling and Evasion of Host Antitumor Immunity, 2020, Cancer Research
  • Interferon lambda in inflammation and autoimmune rheumatic diseases, 2021, Nature Reviews Rheumatology
  • Critical role of interferons in gastrointestinal injury repair, 2021, Nature Communications

Kotenko has collaborated frequently with a number of researchers, including:

  • Varsha Gadiyar
  • Raymond B. Birge
  • David Calianese
  • Mariana S. De Lorenzo
  • Rachael Pulica

Their work has been published repeatedly in several notable journals, indicating areas of sustained research activity:

  • The Journal of Immunology
  • bioRxiv (Cold Spring Harbor Laboratory)
  • Proceedings of the National Academy of Sciences
  • The Journal of Experimental Medicine
  • Cancer Research

Best Publications

  • IFN-lambdas mediate antiviral protection through a distinct class II cytokine receptor complex.

    Sergei V. Kotenko;Grant Gallagher;Vitaliy V. Baurin;Anita Lewis-Antes

  • Role of deficient type III interferon-λ production in asthma exacerbations

    Marco Contoli;Simon D Message;Vasile Laza-Stanca;Michael R Edwards

  • Interferons α and λ Inhibit Hepatitis C Virus Replication With Distinct Signal Transduction and Gene Regulation Kinetics

    Tobias Marcello;Arash Grakoui;Giovanna Barba-Spaeth;Erica S. Machlin

  • Human cytomegalovirus harbors its own unique IL-10 homolog (cmvIL-10)

    Sergei V. Kotenko;Simona Saccani;Lara S. Izotova;Olga V. Mirochnitchenko

  • Identification of the Functional Interleukin-22 (IL-22) Receptor Complex THE IL-10R2 CHAIN (IL-10Rβ) IS A COMMON CHAIN OF BOTH THE IL-10 AND IL-22 (IL-10-RELATED T CELL-DERIVED INDUCIBLE FACTOR, IL-TIF) RECEPTOR COMPLEXES

    Sergei V. Kotenko;Lara S. Izotova;Olga V. Mirochnitchenko;Elena Esterova

  • Cutting Edge: STAT Activation By IL-19, IL-20 and mda-7 Through IL-20 Receptor Complexes of Two Types

    Laure Dumoutier;Caroline Leemans;Diane Lejeune;Sergei V. Kotenko

  • Interferon-lambda: a new addition to an old family.

    Raymond P. Donnelly;Sergei V. Kotenko

  • Interferon-λ Mediates Non-redundant Front-Line Antiviral Protection against Influenza Virus Infection without Compromising Host Fitness.

    Ioanna E. Galani;Vasiliki Triantafyllia;Evridiki Evangelia Eleminiadou;Ourania Koltsida

  • The Human Homologue of the Yeast Proteins Skb1 and Hsl7p Interacts with Jak Kinases and Contains Protein Methyltransferase Activity

    Brian P. Pollack;Sergei V. Kotenko;Wen He;Lara S. Izotova

  • The expanded family of class II cytokines that share the IL-10 receptor-2 (IL-10R2) chain

    Raymond P. Donnelly;Faruk Sheikh;Sergei V. Kotenko;Harold Dickensheets

  • Identification, Cloning, and Characterization of a Novel Soluble Receptor That Binds IL-22 and Neutralizes Its Activity

    Sergei V. Kotenko;Lara S. Izotova;Olga V. Mirochnitchenko;Elena Esterova

  • Role of the interleukin (IL)-28 receptor tyrosine residues for antiviral and antiproliferative activity of IL-29/interferon-lambda 1: similarities with type I interferon signaling.

    Laure Dumoutier;Amel Tounsi;Thomas Michiels;Caroline Sommereyns

  • Lambda Interferon Is the Predominant Interferon Induced by Influenza A Virus Infection In Vivo

    Nancy A. Jewell;Troy Cline;Sara E. Mertz;Sergey V. Smirnov

  • Characterization of the mouse IFN-λ ligand-receptor system: IFN-λs exhibit antitumor activity against B16 melanoma

    Ahmed Lasfar;Anita Lewis-Antes;Sergey V Smirnov;Shubha Anantha

  • Jak-Stat signal transduction pathway through the eyes of cytokine class II receptor complexes.

    Sergei V Kotenko;Sidney Pestka

  • The Class II cytokine receptor (CRF2) family: overview and patterns of receptor-ligand interactions.

    Jerome A Langer;E.Cali Cutrone;Sergei Kotenko

  • Interferon induction and function at the mucosal surface

    Russell K. Durbin;Sergei V. Kotenko;Joan E. Durbin

  • The two groups of zebrafish virus-induced interferons signal via distinct receptors with specific and shared chains.

    Dina Aggad;Martine Mazel;Pierre Boudinot;Knud Erik Mogensen

  • Cutting edge: IL-26 signals through a novel receptor complex composed of IL-20 receptor 1 and IL-10 receptor 2.

    Faruk Sheikh;Vitaliy V. Baurin;Anita Lewis-Antes;Nital K. Shah

  • IL-28A (IFN-λ2) modulates lung DC function to promote Th1 immune skewing and suppress allergic airway disease

    Ourania Koltsida;Michael Hausding;Athanasios Stavropoulos;Sonja Koch

Frequent Co-Authors

Sidney Pestka
Sidney Pestka Rutgers, The State University of New Jersey
Raymond B. Birge
Raymond B. Birge Rutgers, The State University of New Jersey
Joan E. Durbin
Joan E. Durbin Rutgers, The State University of New Jersey
Raymond P. Donnelly
Raymond P. Donnelly US Food and Drug Administration
Laure Dumoutier
Laure Dumoutier Université Catholique de Louvain
Jean-Christophe Renauld
Jean-Christophe Renauld Université Catholique de Louvain
Rune Hartmann
Rune Hartmann Aarhus University
Harry B. Greenberg
Harry B. Greenberg Stanford University
Geoffrey L. Smith
Geoffrey L. Smith University of Oxford
Lionel B. Ivashkiv
Lionel B. Ivashkiv Hospital for Special Surgery

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