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Biology and Biochemistry

D-Index
62
Citations
12947
World Ranking
10854
National Ranking
4707

Overview

Robert N. Fariss is affiliated with the National Institutes of Health in the United States. Their research spans several areas within medicine, with a primary focus on biochemistry, genetics, and molecular biology. Their investigations are particularly oriented toward the study of retinal development and disorders, retinal diseases and treatments, as well as mechanisms of neuroinflammation and neurodegeneration.

Fariss has contributed extensively to the fields of molecular biology and ophthalmology, among others. Their work also touches on neurology, radiology, nuclear medicine, infectious diseases, and various aspects of cellular transport and secretion.

Frequent co-authors in Fariss's research include Biying Xu, Anand Swaroop, Camasamudram Vijayasarathy, Lijin Dong, and Paul A. Sieving.

Notable publication venues for their work include eLife, bioRxiv (Cold Spring Harbor Laboratory), Investigative Ophthalmology & Visual Science, Human Gene Therapy, and Progress in Retinal and Eye Research.

Recent papers associated with Robert N. Fariss include the following:

  • Genetic Rescue of X-Linked Retinoschisis Mouse ( Rs1 −/y ) Retina Induces Quiescence of the Retinal Microglial Inflammatory State Following AAV8- RS1 Gene Transfer and Identifies Gene Networks Underlying Retinal Recovery, 2020, Human Gene Therapy
  • Targeted Expression of Retinoschisin by Retinal Bipolar Cells in XLRS Promotes Resolution of Retinoschisis Cysts Sans RS1 From Photoreceptors, 2022, Investigative Ophthalmology & Visual Science
  • Advances in understanding the molecular structure of retinoschisin while questions remain of biological function, 2022, Progress in Retinal and Eye Research
  • Loss of endocytosis-associated RabGEF1 causes aberrant morphogenesis and altered autophagy in photoreceptors leading to retinal degeneration, 2020, PLoS Genetics
  • Widespread subclinical cellular changes revealed across a neural-epithelial-vascular complex in choroideremia using adaptive optics, 2022, Communications Biology

Best Publications

  • Histopathology of the human retina in retinitis pigmentosa

    A H Milam;Z Y Li;R N Fariss

  • Age-Related Macular Degeneration: Genetics and Biology Coming Together

    Lars G. Fritsche;Robert N. Fariss;Dwight Stambolian;Gonçalo R. Abecasis

  • Age-related alterations in the dynamic behavior of microglia.

    Mausam R. Damani;Lian Zhao;Aurora M. Fontainhas;Juan Amaral

  • Microglial phagocytosis of living photoreceptors contributes to inherited retinal degeneration.

    Lian Zhao;Matthew K Zabel;Xu Wang;Wenxin Ma

  • Microglial morphology and dynamic behavior is regulated by ionotropic glutamatergic and GABAergic neurotransmission.

    Aurora M. Fontainhas;Minhua Wang;Katharine J. Liang;Shan Chen

  • VEGF-B is dispensable for blood vessel growth but critical for their survival, and VEGF-B targeting inhibits pathological angiogenesis

    Fan Zhang;Zhongshu Tang;Xu Hou;Johan Lennartsson

  • Abnormalities in rod photoreceptors, amacrine cells, and horizontal cells in human retinas with retinitis pigmentosa

    Robert N Fariss;Zong-Yi Li;Ann H Milam;Ann H Milam

  • Five Members of a Novel Ca2+-binding Protein (CABP) Subfamily with Similarity to Calmodulin

    Françoise Haeseleer;Izabela Sokal;Christophe L. M. J. Verlinde;Hediye Erdjument-Bromage

  • Requirement for Microglia for the Maintenance of Synaptic Function and Integrity in the Mature Retina

    Xu Wang;Lian Zhao;Jun Zhang;Robert N. Fariss

  • New views on RPE65 deficiency: the rod system is the source of vision in a mouse model of Leber congenital amaurosis.

    Mathias W. Seeliger;Christian Grimm;Fredrik Ståhlberg;Fredrik Ståhlberg;Christoph Friedburg

  • Microglia in the Mouse Retina Alter the Structure and Function of Retinal Pigmented Epithelial Cells: A Potential Cellular Interaction Relevant to AMD

    Wenxin Ma;Lian Zhao;Aurora M. Fontainhas;Robert N. Fariss

  • Ex Vivo Dynamic Imaging of Retinal Microglia Using Time-Lapse Confocal Microscopy

    Jung Eun Lee;Katharine J. Liang;Robert N. Fariss;Wai T. Wong

  • Adaptive Müller cell responses to microglial activation mediate neuroprotection and coordinate inflammation in the retina

    Minhua Wang;Wenxin Ma;Lian Zhao;Robert N Fariss

  • Regulation of dynamic behavior of retinal microglia by CX3CR1 signaling.

    Katharine J. Liang;Jung Eun Lee;Yunqing D. Wang;Wenxin Ma

  • Macroglia-Microglia Interactions via TSPO Signaling Regulates Microglial Activation in the Mouse Retina

    Minhua Wang;Xu Wang;Lian Zhao;Wenxin Ma

  • High expression levels in cones of RGS9, the predominant GTPase accelerating protein of rods

    Christopher W. Cowan;Robert N. Fariss;Izabela Sokal;Krzysztof Palczewski

  • Uptake of cholesterol by the retina occurs primarily via a low density lipoprotein receptor-mediated process.

    Nomingerel Tserentsoodol;Jorge Sztein;Mercedes Campos;Natalya V Gordiyenko

  • Tissue inhibitor of metalloproteinases-3 is a component of Bruch's membrane of the eye.

    Robert N. Fariss;Suneel S. Apte;Bjorn R. Olsen;Kazushi Iwata

  • Expression of Mutated Mouse Myocilin Induces Open-Angle Glaucoma in Transgenic Mice

    Vladimir Senatorov;Irina Malyukova;Robert Fariss;Eric F. Wawrousek

  • Disruption of microfilament organization and deregulation of disk membrane morphogenesis by cytochalasin D in rod and cone photoreceptors.

    David S. Williams;Kenneth A. Linberg;Dana K. Vaughan;Robert N. Fariss

Frequent Co-Authors

Anand Swaroop
Anand Swaroop National Institutes of Health
Paul A. Sieving
Paul A. Sieving University of California, Davis
Chi-Chao Chan
Chi-Chao Chan National Institutes of Health
Robert B. Nussenblatt
Robert B. Nussenblatt National Institutes of Health
Graeme Wistow
Graeme Wistow National Institutes of Health
Eric F. Wawrousek
Eric F. Wawrousek National Institutes of Health
Steven K. Fisher
Steven K. Fisher University of California, Santa Barbara
Krzysztof Palczewski
Krzysztof Palczewski University of California, Irvine
Tiansen Li
Tiansen Li National Institutes of Health
Igal Gery
Igal Gery National Institutes of Health

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