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Thomas Langmann

Thomas Langmann

D-Index & Metrics

Biology and Biochemistry

D-Index
71
Citations
21020
World Ranking
6567
National Ranking
469

Overview

Thomas Langmann is affiliated with the University of Cologne in Germany. Their research spans multiple fields primarily within Medicine, Biochemistry, Genetics and Molecular Biology, and Neuroscience. This interdisciplinary approach reflects a focus on complex biological systems and diseases, especially related to the eye and nervous system.

The scientist has contributed extensively to subfields such as Ophthalmology, Neurology, Immunology, Molecular Biology, and Genetics. This specialization supports a body of work centered on understanding mechanisms underlying ocular and neurological conditions.

Langmann's main research topics include Neuroinflammation and Neurodegeneration Mechanisms, Retinal Diseases and Treatments, Retinal Development and Disorders, Immune Cells in Cancer, Ocular Diseases and Behçet's Syndrome, Genetic and Kidney Cyst Diseases, and Glaucoma and Retinal Disorders.

Recent papers authored or co-authored by Langmann include:

  • VEGFR1 signaling in retinal angiogenesis and microinflammation, 2021, Progress in Retinal and Eye Research
  • Microglia and Inflammatory Responses in Diabetic Retinopathy, 2020, Frontiers in Immunology
  • Past history of obesity triggers persistent epigenetic changes in innate immunity and exacerbates neuroinflammation, 2023, Science
  • A mega-analysis of expression quantitative trait loci in retinal tissue, 2020, PLoS Genetics
  • The TSPO-NOX1 axis controls phagocyte-triggered pathological angiogenesis in the eye, 2020, Nature Communications

Frequent publication venues for Langmann include the Journal of Neuroinflammation, Progress in Retinal and Eye Research, Frontiers in Immunology, Cellular and Molecular Life Sciences, and Biochemical and Biophysical Research Communications. These journals reflect the blend of neurobiological and ophthalmological themes in the scientist's work.

Collaboration is a significant aspect of Langmann's research output. Frequent co-authors include Anne Wolf, Mandy Hector, Verena Behnke, Urbanus Muthai Kinuthia, and Marcus Karlstetter, indicating a collaborative network active in related scientific domains.

Best Publications

  • The gene encoding ATP-binding cassette transporter 1 is mutated in Tangier disease

    Marek Bodzioch;Evelyn Orsó;Jochen Klucken;Thomas Langmann

  • A large genome-wide association study of age-related macular degeneration highlights contributions of rare and common variants

    Lars G. Fritsche;Wilmar Igl;Jessica N.Cooke Bailey;Felix Grassmann

  • Regulation of scavenger receptor CD163 expression in human monocytes and macrophages by pro- and antiinflammatory stimuli.

    Christa Buechler;Mirko Ritter;Evelyn Orsó;Thomas Langmann

  • Molecular cloning of the human ATP-binding cassette transporter 1 (hABC1): evidence for sterol-dependent regulation in macrophages.

    Thomas Langmann;Jochen Klucken;Markus Reil;Gerhard Liebisch

  • Retinal microglia: Just bystander or target for therapy?

    Marcus Karlstetter;Rebecca Scholz;Matt Rutar;Wai T. Wong

  • Microglia activation in retinal degeneration.

    Thomas Langmann

  • Transport of lipids from Golgi to plasma membrane is defective in Tangier disease patients and Abc1 -deficient mice

    Evelyn Orsó;Cyril Broccardo;Wolfgang E. Kaminski;Alfred Böttcher

  • High throughput quantification of cholesterol and cholesteryl ester by electrospray ionization tandem mass spectrometry (ESI-MS/MS)

    Gerhard Liebisch;Marion Binder;Rainer Schifferer;Thomas Langmann

  • Differential Gene Expression of Eph Receptors and Ephrins in Benign Human Tissues and Cancers

    Christian Hafner;Gerd Schmitz;Stefanie Meyer;Frauke Bataille

  • Glioma-associated microglia/macrophages display an expression profile different from M1 and M2 polarization and highly express Gpnmb and Spp1.

    Frank Szulzewsky;Andreas Pelz;Xi Feng;Michael Synowitz

  • Loss of detoxification in inflammatory bowel disease: dysregulation of pregnane X receptor target genes.

    Thomas Langmann;Christoph Moehle;Richard Mauerer;Michael Scharl

  • Real-Time Reverse Transcription-PCR Expression Profiling of the Complete Human ATP-Binding Cassette Transporter Superfamily in Various Tissues

    Thomas Langmann;Richard Mauerer;Alexandra Zahn;Christoph Moehle

  • Role of ABCG1 and other ABCG family members in lipid metabolism

    Gerd Schmitz;Thomas Langmann;Susanne Heimerl

  • Postzygotic HRAS and KRAS mutations cause nevus sebaceous and Schimmelpenning syndrome.

    Leopold Groesser;Eva Herschberger;Arno Ruetten;Claudia Ruivenkamp

  • Transcriptional regulatory networks in lipid metabolism control ABCA1 expression

    Gerd Schmitz;Thomas Langmann

  • Microglia in Retinal Degeneration.

    Khalid Rashid;Isha Akhtar-Schaefer;Thomas Langmann

  • Structure, function and regulation of the ABC1 gene product.

    Gerd Schmitz;Thomas Langmann

  • Microglia in the healthy and degenerating retina: Insights from novel mouse models

    Marcus Karlstetter;Stefanie Ebert;Thomas Langmann

  • CRX ChIP-seq reveals the cis-regulatory architecture of mouse photoreceptors

    Joseph C. Corbo;Karen A. Lawrence;Marcus Karlstetter;Connie A. Myers

  • Aberrant intestinal expression and allelic variants of mucin genes associated with inflammatory bowel disease.

    Christoph Moehle;Nikolaus Ackermann;Nikolaus Ackermann;Thomas Langmann;Charalampos Aslanidis

Frequent Co-Authors

Gerd Schmitz
Gerd Schmitz University of Regensburg
Bernhard H. F. Weber
Bernhard H. F. Weber University of Regensburg
Elfride De Baere
Elfride De Baere Ghent University
Gerhard Liebisch
Gerhard Liebisch University of Regensburg
Wolfgang Stremmel
Wolfgang Stremmel Heidelberg University
Harald Neumann
Harald Neumann University of Bonn
Christian Grimm
Christian Grimm University of Zurich
Anneke I. den Hollander
Anneke I. den Hollander Radboud University
Andrew R. Webster
Andrew R. Webster University College London

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