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Chemistry

D-Index
70
Citations
25004
World Ranking
5743
National Ranking
331

Research.com Recognitions

  • 2006 - Tilden Prize, Royal Society of Chemistry (UK)

Overview

David O'Hagan is affiliated with the University of St Andrews in the United Kingdom. Their research focuses primarily on Materials Science and Chemistry, with significant contributions in subfields including Materials Chemistry, Organic Chemistry, Pharmaceutical Science, Molecular Biology, and Spectroscopy.

Their work covers several core topics, notably:

  • Crystallization and Solubility Studies
  • X-ray Diffraction in Crystallography
  • Fluorine in Organic Chemistry
  • Carbohydrate Chemistry and Synthesis
  • Chemical Synthesis and Analysis
  • Click Chemistry and Applications
  • Synthesis and Reactions of Organic Compounds

Recent publications reflect a focus on fluorine chemistry and its applications in drug development and biofluorination processes. Notable papers include:

  • Next generation organofluorine containing blockbuster drugs, 2020, Journal of Fluorine Chemistry
  • A fluoride-responsive genetic circuit enables in vivo biofluorination in engineered Pseudomonas putida, 2020, Nature Communications
  • Polar Organofluorine Substituents: Multivicinal Fluorines on Alkyl Chains and Alicyclic Rings, 2020, Chemistry - A European Journal
  • Future challenges and opportunities with fluorine in drugs?, 2023, Medicinal Chemistry Research
  • An Engineered E. coli Strain for Direct in Vivo Fluorination, 2020, ChemBioChem

David O'Hagan frequently collaborates with several other scientists, including:

  • David B. Cordes
  • Alexandra M. Z. Slawin
  • Cihang Yu
  • Rodrigo A. Cormanich
  • Bruno A. Piscelli

Their work has been published extensively in venues such as:

  • The Cambridge Structural Database
  • Chemistry - A European Journal
  • ChemBioChem
  • European Journal of Organic Chemistry
  • Journal of Fluorine Chemistry

David O'Hagan received the Tilden Prize from the Royal Society of Chemistry (UK) in 2006.

Best Publications

  • Understanding organofluorine chemistry. An introduction to the C–F bond

    David O'Hagan

  • Pyrrole, pyrrolidine, pyridine, piperidine and tropane alkaloids

    David O’Hagan

  • Fluorine in medicinal chemistry: A review of anti-cancer agents

    Chukwuemeka Isanbor;David O’Hagan

  • How good is fluorine as a hydrogen bond acceptor

    Judith A.K. Howard;Vanessa J. Hoy;David O'Hagan;Garry T. Smith

  • Fluorine in health care: Organofluorine containing blockbuster drugs

    David O’Hagan

  • Successful fluorine-containing herbicide agrochemicals

    Tomoya Fujiwara;Tomoya Fujiwara;David O’Hagan

  • Biochemistry: biosynthesis of an organofluorine molecule.

    David O'Hagan;Christoph Schaffrath;Steven L. Cobb;John T. G. Hamilton

  • The polyketide metabolites

    David O'Hagan

  • Fluorine-containing natural products

    David O’Hagan;David B. Harper

  • Some influences of fluorine in bioorganic chemistry

    David O’Hagan;Henry S. Rzepa

  • Crystal structure and mechanism of a bacterial fluorinating enzyme

    Changjiang Dong;Fanglu Huang;Hai Deng;Christoph Schaffrath

  • Enzymatic fluorination and biotechnological developments of the fluorinase.

    David O’Hagan;Hai Deng

  • The fluorinated natural products

    D. B. Harper;D. O'Hagan

  • Next generation organofluorine containing blockbuster drugs

    Jianlin Han;Attila Márió Remete;Luca S. Dobson;Lorand Kiss

  • Pyrrole, pyrrolidine pyridine, piperidine, azepine and tropane alkaloids

    David O'Hagan

  • Biosynthesis of fatty acid and polyketide metabolites

    David O'Hagan

  • Catalytic Asymmetric Fluorination Comes of Age

    Vincent A. Brunet;David O'Hagan

  • Influence of the difluoromethylene group (CF 2 ) on the conformation and properties of selected organic compounds

    David O'Hagan;Yi Wang;Maciej Skibinski;Alexandra M. Z. Slawin

  • Tropane alkaloid biosynthesis. A century old problem unresolved.

    Andrew J. Humphrey;David O'Hagan

  • All-cis 1,2,3,4,5,6-hexafluorocyclohexane is a facially polarized cyclohexane

    Neil Steven Keddie;Alexandra Martha Zoya Slawin;Tomas Lebl;Douglas Philp

  • Synthesis of monofluoro- and difluoro- methylenephosphonate analogues of sn-glycerol-3-phosphate as substrates for glycerol-3-phosphate dehydrogenase and the X-ray structure of the fluoromethylenephosphonate moiety

    Jens Nieschalk;Andrei S Batsanov;David O'Hagan;Judith Howard

  • Fluorine in Medicinal Chemistry: A Review of Anticancer Agents

    Chukwuemeka Isanbor;David O'Hagan

Frequent Co-Authors

Alexandra M. Z. Slawin
Alexandra M. Z. Slawin University of St Andrews
James H. Naismith
James H. Naismith Rosalind Franklin Institute
Michael Bühl
Michael Bühl University of St Andrews
David B. Cordes
David B. Cordes University of St Andrews
Judith A. K. Howard
Judith A. K. Howard Durham University
Henry S. Rzepa
Henry S. Rzepa Imperial College London
Andrei S. Batsanov
Andrei S. Batsanov Durham University
Steven P. Nolan
Steven P. Nolan Ghent University
David J. Tozer
David J. Tozer Durham University
Michael C. Petty
Michael C. Petty Durham University

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