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D-Index & Metrics

Biology and Biochemistry

D-Index
50
Citations
7137
World Ranking
17774
National Ranking
7273

Overview

Phang C. Tai is affiliated with Georgia State University in the United States and has contributed to research primarily in the fields of Biochemistry, Genetics and Molecular Biology, and Medicine. Their work spans several subfields including Molecular Biology, Molecular Medicine, Infectious Diseases, Geriatrics and Gerontology, and Dermatology.

Their research topics encompass a range of areas with a strong emphasis on cancer therapeutics and mechanisms, antibiotic resistance in bacteria, and the synthesis and activities of phenothiazines and benzothiazines. Additional topics include sirtuins and resveratrol in medicine, skin protection and aging, tea polyphenols and their effects, and bacterial genetics and biotechnology.

Phang C. Tai has collaborated frequently with a group of co-authors, including Jinshan Jin, Binghe Wang, Fanté Bamba, Arpana S. Chaudhary, and Su-Ying Wen.

The scientist's recent publications highlight their involvement in both biochemical and pharmaceutical research. These include:

  • Enhanced SIRT1 Activity by Galangin Mitigates UVB-Induced Senescence in Dermal Fibroblasts via p53 Acetylation Regulation and Activation, 2024, Journal of Agricultural and Food Chemistry
  • Synthesis and biological evaluation of novel 4-oxo-5-cyano thiouracil derivatives as SecA inhibitors, 2020, Heterocyclic Communications
  • Design, synthesis, and biological evaluation of pyrimidine analogs as SecA inhibitors, 2021, Medicinal Chemistry Research
  • Thiouracil SecA inhibitors: bypassing the effects of efflux pumps and attenuating virulence factor secretion in MRSA and Bacillus anthracis, 2021, Medicinal Chemistry Research
  • Evaluation of the Seca Inhibitors as Novel Anti-Microbial Agents, 2022, Counseling And Psychological Services Dissertations (Georgia State University)

The notable publication venues where Phang C. Tai has published include Medicinal Chemistry Research, Journal of Agricultural and Food Chemistry, Heterocyclic Communications, Counseling And Psychological Services Dissertations at Georgia State University, and Research Square.

Best Publications

  • The mechanism of protein secretion across membranes

    Bernard D. Davis;Phang-C. Tai

  • Misread protein creates membrane channels: an essential step in the bactericidal action of aminoglycosides

    Bernard D. Davis;Lingling Chen;Phang C. Tai

  • SecA protein is required for secretory protein translocation into E. coli membrane vesicles

    Robert J. Cabelli;Lingling Chen;Phang C. Tai;Donald B. Oliver

  • ATP is essential for protein translocation into Escherichia coli membrane vesicles.

    Lingling Chen;Phang C. Tai

  • Extracellular labeling of nascent polypeptides traversing the membrane of Escherichia coli.

    Walter P. Smith;Phang-C. Tai;Robert C. Thompson;Bernard D. Davis

  • Improved K-means clustering algorithm for exploring local protein sequence motifs representing common structural property

    Wei Zhong;G. Altun;R. Harrison;P.C. Tai

  • Cloning, characterization and expression of escapin, a broadly antimicrobial FAD-containing L-amino acid oxidase from ink of the sea hare Aplysia californica.

    Hsiuchin Yang;Paul Micah Johnson;Paul Micah Johnson;Ko-Chun Ko;Michiya Kamio

  • Mechanism of protein excretion by gram-negative bacteria: Pseudomonas aeruginosa exotoxin A.

    S Lory;P C Tai;B D Davis

  • A Significant Fraction of Functional SecA Is Permanently Embedded in the Membrane: SecA CYCLING ON AND OFF THE MEMBRANE IS NOT ESSENTIAL DURING PROTEIN TRANSLOCATION

    Xianchuan Chen;Haoda Xu;Phang C. Tai

  • Nonclassical Protein Secretion by Bacillus subtilis in the Stationary Phase Is Not Due to Cell Lysis

    Chun-Kai Yang;Hosam E. Ewis;XiaoZhou Zhang;XiaoZhou Zhang;Chung-Dar Lu

  • Alkaline phosphatase and OmpA protein can be translocated posttranslationally into membrane vesicles of Escherichia coli.

    Lingling Chen;D. Rhoads;P. C. Tai

  • Improved protein secondary structure prediction using support vector machine with a new encoding scheme and an advanced tertiary classifier

    Hae-Jin Hu;Yi Pan;R. Harrison;P.C. Tai

  • Novel hybrid hierarchical-K-means clustering method (H-K-means) for microarray analysis

    B. Chen;P.C. Tai;R. Harrison;Yi Pan

  • Purification of the Escherichia coli secB gene product and demonstration of its activity in an in vitro protein translocation system.

    C. A. Kumamoto;Lingling Chen;J. Fandl;P. C. Tai

  • Energy-requiring translocation of the OmpA protein and alkaline phosphatase of Escherichia coli into inner membrane vesicles.

    D B Rhoads;P C Tai;B D Davis

  • Genetic analysis of the colicin V secretion pathway.

    Li Hong Zhang;M. J. Fath;H. K. Mahanty;P. C. Tai

  • Ring-like pore structures of SecA: implication for bacterial protein-conducting channels.

    Hong-Wei Wang;Yong Chen;Hsiuchin Yang;Xianchuan Chen

  • Interactions of Dedicated Export Membrane Proteins of the Colicin V Secretion System: CvaA, a Member of the Membrane Fusion Protein Family, Interacts with CvaB and TolC

    Jaiweon Hwang;Xiaotian Zhong;Phang C. Tai

  • Selective action of erythromycin on initiating ribosomes.

    Phang-Cheng Tai;Brian J. Wallace;Bernard D. Davis

  • Nascent peptide as sole attachment of polysomes to membranes in bacteria.

    Walter P. Smith;Phang-C. Tai;Bernard D. Davis

Frequent Co-Authors

Robert J. Harrison
Robert J. Harrison Murdoch University
Yi Pan
Yi Pan Shenzhen Institutes of Advanced Technology
Binghe Wang
Binghe Wang Georgia State University
Charles D. Derby
Charles D. Derby Georgia State University
Minyong Li
Minyong Li Shandong University
Bernard D. Davis
Bernard D. Davis Harvard University
Irene T. Weber
Irene T. Weber Georgia State University
Lila M. Gierasch
Lila M. Gierasch University of Massachusetts Amherst
Martti Vaara
Martti Vaara University of Helsinki
Roberto Kolter
Roberto Kolter Harvard University

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