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Hajime Tokuda

Hajime Tokuda

D-Index & Metrics

Biology and Biochemistry

D-Index
62
Citations
11422
World Ranking
10986
National Ranking
752

Overview

Hajime Tokuda is affiliated with the University of Tokyo in Japan and conducts research primarily in the fields of Biochemistry, Genetics, and Molecular Biology, with contributions also relevant to Medicine.

Their work spans several subfields including Genetics, Oncology, and Molecular Biology, reflecting an interdisciplinary approach to understanding biological processes at the molecular level. Key research topics include Bacterial Genetics and Biotechnology, Drug Transport and Resistance Mechanisms, and RNA and protein synthesis mechanisms.

Hajime Tokuda's recent publication includes the paper "Dissection of an ABC transporter LolCDE function analyzed by photo-crosslinking" published in 2023 in The Journal of Biochemistry. This work involved detailed analysis of protein function relating to membrane transport systems in bacteria.

Frequent co-authors collaborating with Hajime Tokuda are:

  • Kazuyuki Tao
  • Shin-ichiro Narita
  • Ui Okada
  • Satoshi Murakami

Tokuda's publication record includes contributions to the following venue:

  • The Journal of Biochemistry

Best Publications

  • Lipoprotein Sorting in Bacteria

    Suguru Okuda;Hajime Tokuda

  • Sorting of lipoproteins to the outer membrane in E. coli.

    Hajime Tokuda;Shin-ichi Matsuyama

  • A new ABC transporter mediating the detachment of lipid-modified proteins from membranes.

    Toshiharu Yakushi;Kazuhiro Masuda;Shin-ichiro Narita;Shin-ichi Matsuyama

  • Inversion of the Membrane Topology of SecG Coupled with SecA-Dependent Preprotein Translocation

    Ken-ichi Nishiyama;Takashi Suzuki;Hajime Tokuda

  • Reconstitution of a protein translocation system containing purified SecY, SecE, and SecA from Escherichia coli.

    Jiro Akimaru;Shin-Ichi Matsuyama;Hajime Tokuda;Shoji Mizushima

  • A novel outer membrane lipoprotein, LolB (HemM), involved in the LolA (p20)‐dependent localization of lipoproteins to the outer membrane of Escherichia coli

    Shin‐ichi Matsuyama;Naoko Yokota;Hajime Tokuda

  • A novel periplasmic carrier protein involved in the sorting and transport of Escherichia coli lipoproteins destined for the outer membrane.

    S.-I. Matsuyama;T. Tajima;H. Tokuda

  • Disruption of the gene encoding p12 (SecG) reveals the direct involvement and important function of SecG in the protein translocation of Escherichia coli at low temperature.

    K.-I. Nishiyama;M. Hanada;H. Tokuda

  • FtsH (HflB) is an ATP-dependent protease selectively acting on SecY and some other membrane proteins.

    Yoshinori Akiyama;Akio Kihara;Hajime Tokuda;Koreaki Ito

  • A novel membrane protein involved in protein translocation across the cytoplasmic membrane of Escherichia coli.

    K.-I. Nishiyama;S. Mizushima;H. Tokuda

  • Crystal structures of bacterial lipoprotein localization factors, LolA and LolB

    Kazuki Takeda;Hideyuki Miyatake;Naoko Yokota;Shin‐ichi Matsuyama

  • Biogenesis of outer membranes in Gram-negative bacteria.

    Hajime Tokuda

  • Biochemical characterization of an ABC transporter LptBFGC complex required for the outer membrane sorting of lipopolysaccharides.

    Shin-ichiro Narita;Hajime Tokuda

  • Translocation of ProOmpA possessing an intramolecular disulfide bridge into membrane vesicles of Escherichia coli : effect of membrane energization

    K Tani;H Tokuda;S Mizushima

  • Reconstitution of an efficient protein translocation machinery comprising SecA and the three membrane proteins, SecY, SecE, and SecG (p12).

    M Hanada;K I Nishiyama;S Mizushima;H Tokuda

  • Lethality of the covalent linkage between mislocalized major outer membrane lipoprotein and the peptidoglycan of Escherichia coli.

    Toshiharu Yakushi;Terutaka Tajima;Shin-Ichi Matsuyama;Hajime Tokuda

  • Lipoprotein trafficking in Escherichia coli

    Shin-ichiro Narita;Shin-ichi Matsuyama;Shin-ichi Matsuyama;Hajime Tokuda

  • Model of mouth-to-mouth transfer of bacterial lipoproteins through inner membrane LolC, periplasmic LolA, and outer membrane LolB

    Suguru Okuda;Hajime Tokuda

  • Lipoprotein sorting signals evaluated as the LolA-dependent release of lipoproteins from the cytoplasmic membrane of Escherichia coli.

    Makiko Terada;Toshiro Kuroda;Shin-ichi Matsuyama;Hajime Tokuda

  • Elucidation of the function of lipoprotein-sorting signals that determine membrane localization.

    Kazuhiro Masuda;Shin-ichi Matsuyama;Hajime Tokuda

Frequent Co-Authors

Shoji Mizushima
Shoji Mizushima University of Tokyo
Kunio Miki
Kunio Miki Kyoto University
Ichio Shimada
Ichio Shimada University of Tokyo
Shoichi Kusumoto
Shoichi Kusumoto Osaka University
Akio Kihara
Akio Kihara Hokkaido University
Koreaki Ito
Koreaki Ito Kyoto Sangyo University
Jiro Nakayama
Jiro Nakayama Kyushu University
Yoshinori Akiyama
Yoshinori Akiyama Kyoto University
William Wickner
William Wickner Dartmouth College
Yoshiaki Kawamura
Yoshiaki Kawamura Aichi Gakuin University

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