World's Best Scientists 2026 revealed!

D-Index & Metrics

Biology and Biochemistry

D-Index
66
Citations
30432
World Ranking
8445
National Ranking
3802

Overview

Owen W. Griffith is affiliated with the Medical College of Wisconsin in the United States. Their research activity spans across medicine with a particular focus on epidemiology and cognitive neuroscience, alongside work in public health, environmental and occupational health, psychiatry and mental health, and biochemistry.

Their main research topics include traumatic brain injury research, functional brain connectivity studies, antioxidant activity and oxidative stress, retinoids in leukemia and cellular processes, vitamin C and antioxidants research, advanced neuroimaging techniques and applications, and musculoskeletal disorders and rehabilitation.

Griffith has published in a range of academic venues. Notable publication outlets include Discover Medicine, Frontiers in Neurology, BMJ, Archives of Clinical Neuropsychology, and Brain Research. Their work is frequently co-authored by other researchers such as Semyon Slobounov, Jon Kelly, Linda Papa, Xiaoxiao Bai, and Lacy M. Alexander.

Recent papers authored or co-authored by Griffith include:

  • Association of player position and functional connectivity alterations in collegiate American football players: an fMRI study, 2025, Frontiers in Neurology
  • Maldwyn Jones Griffith, 2020, BMJ
  • Comorbidity of concussion and depression alters brain functional connectivity in collegiate student-athletes, 2024, Brain Research

Other recent studies relevant to their field include:

  • Perspective: supplementation with macular pigment carotenoids with respect to brain injury, 2025, Discover Medicine
  • A-67 Examining Demographic Influence on Virtual Reality Cognitive Scores in Division I Collegiate Football Players, 2023, Archives of Clinical Neuropsychology

Owen W. Griffith's work integrates advanced neuroimaging techniques to study brain function and connectivity, particularly in the context of brain injuries and their psychological and physiological impacts. Their research addresses complex interactions between concussions, depression, and functional connectivity in athletes, highlighting cognitive neuroscience and epidemiological approaches.

Best Publications

  • DETERMINATION OF GLUTATHIONE AND GLUTATHIONE DISULFIDE USING GLUTATHIONE REDUCTASE AND 2-VINYLPYRIDINE

    Owen W. Griffith

  • Nitric Oxide Synthases: Properties and Catalytic Mechanism

    O W Griffith;D J Stuehr

  • Biologic and pharmacologic regulation of mammalian glutathione synthesis.

    Owen W. Griffith

  • Mammalian nitric oxide synthases.

    Dennis J Stuehr

  • NG-methyl-L-arginine inhibits tumor necrosis factor-induced hypotension: implications for the involvement of nitric oxide.

    Robert G. Kilbourn;Steven S. Gross;Amal Jubran;James Adams

  • Glutathione: interorgan translocation, turnover, and metabolism.

    Owen W. Griffith;Alton Meister

  • N omega-hydroxy-L-arginine is an intermediate in the biosynthesis of nitric oxide from L-arginine.

    Dennis J Stuehr;Nyoun Soo Kwon;Carl F. Nathan;Owen W. Griffith

  • Reversal of endotoxin-mediated shock by NG-methyl-L-arginine, an inhibitor of nitric oxide synthesis.

    Robert G. Kilbourn;Amal Jubran;Steven S. Gross;Owen W. Griffith

  • Mammalian nitric oxide synthases.

    D J Stuehr;O W Griffith

  • Origin and turnover of mitochondrial glutathione.

    Owen W. Griffith;Alton Meister

  • NG-methylarginine, and inhibitor of endothelium-derived nitric oxide synthesis, is a potent pressor agent in the guinea pig: Does nitric oxide regulate blood pressure in vivo?

    Kazuo Aisaka;Steven S. Gross;Owen W. Griffith;Roberto Levi

  • Gamma-glutamyl transpeptidase.

    Alton Meister;Suresh S. Tate;Owen W. Griffith

  • The surprising life of nitric oxide

    Paul L. Feldman;Owen W. Griffith;Dennis J Stuehr

  • Macrophage and endothelial cell nitric oxide synthesis: Cell-type selective inhibition by NG-aminoarginine, NG-nitroarginine and NG-methylarginine

    Steven S. Gross;Dennis J. Stuehr;Kazuo Aisaka;Eric A. Jaffe

  • Overproduction of nitric oxide in cytokine-mediated and septic shock.

    Robert G. Kilbourn;Owen W. Griffith

  • The enzymes of glutathione synthesis: gamma-glutamylcysteine synthetase.

    O W Griffith;R T Mulcahy

  • L-citrulline production from L-arginine by macrophage nitric oxide synthase. The ureido oxygen derives from dioxygen.

    Nyoun Soo Kwon;Carl F. Nathan;Charles Gilker;Owen W. Griffith

  • Mammalian sulfur amino acid metabolism: an overview.

    Owen W. Griffith

  • Translocation of intracellular glutathione to membrane-bound γ-glutamyl transpeptidase as a discrete step in the γ-glutamyl cycle: Glutathionuria after inhibition of transpeptidase

    Owen W. Griffith;Alton Meister

  • Glutathione depletion sensitizes tumor cells to oxidative cytolysis.

    B A Arrick;C F Nathan;O W Griffith;Z A Cohn

Frequent Co-Authors

Steven S. Gross
Steven S. Gross Cornell University
Darell D. Bigner
Darell D. Bigner Duke University
Henry S. Friedman
Henry S. Friedman Duke University
Jonathan S. Stamler
Jonathan S. Stamler Case Western Reserve University
Dennis J. Stuehr
Dennis J. Stuehr Cleveland Clinic Lerner College of Medicine
Gertrude B. Elion
Gertrude B. Elion Duke University
Arthur J. L. Cooper
Arthur J. L. Cooper New York Medical College
Zanvil A. Cohn
Zanvil A. Cohn Rockefeller University
Alton Meister
Alton Meister Cornell University
Carl Nathan
Carl Nathan Cornell University

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