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Biology and Biochemistry

D-Index
43
Citations
9378
World Ranking
19368
National Ranking
79

Overview

Oliver E. Blacque is affiliated with University College Dublin in Ireland and specializes in Biochemistry, Genetics, and Molecular Biology.

Their research covers several specific subfields including Molecular Biology, Genetics, Cell Biology, Aging, and Pediatrics, Perinatology and Child Health.

Blacque's work spans multiple main topics such as Genetic and Kidney Cyst Diseases, Protist diversity and phylogeny, Retinal Development and Disorders, Renal and related cancers, Genetics, Aging, and Longevity in Model Organisms, Microtubule and mitosis dynamics, and Fetal and Pediatric Neurological Disorders.

Recent papers authored or coauthored by Blacque include:

  • "Ciliary Rab28 and the BBSome negatively regulate extracellular vesicle shedding" (2020), published in eLife
  • "CDKL kinase regulates the length of the ciliary proximal segment" (2021), published in Current Biology
  • "Transport and barrier mechanisms that regulate ciliary compartmentalization and ciliopathies" (2023), published in Nature Reviews Nephrology
  • "Interpreting the pathogenicity of Joubert syndrome missense variants in Caenorhabditis elegans" (2020), published in Disease Models & Mechanisms
  • "The inner junction protein CFAP20 functions in motile and non-motile cilia and is critical for vision" (2022), published in Nature Communications

Blacque frequently collaborates with colleagues including:

  • Sofia Tsiropoulou
  • Karen I. Lange
  • Ailís Moran
  • Breandán N. Kennedy
  • Stephen P. Carter

Their publications appear often in venues such as:

  • bioRxiv (Cold Spring Harbor Laboratory)
  • Nature Communications
  • Current Biology
  • Nature Reviews Nephrology
  • Nucleic Acids Research

Best Publications

  • Comparative Genomics Identifies a Flagellar and Basal Body Proteome that Includes the BBS5 Human Disease Gene

    Jin Billy Li;Jantje M Gerdes;Courtney J Haycraft;Yanli Fan

  • Basal body dysfunction is a likely cause of pleiotropic Bardet–Biedl syndrome

    Stephen J. Ansley;Jose L. Badano;Oliver E. Blacque;Josephine Hill

  • The base of the cilium: roles for transition fibres and the transition zone in ciliary formation, maintenance and compartmentalization

    Jeremy F Reiter;Oliver E Blacque;Michel R Leroux

  • Functional coordination of intraflagellar transport motors

    Guangshuo Ou;Oliver E. Blacque;Joshua J. Snow;Michel R. Leroux

  • Loss of C. elegans BBS-7 and BBS-8 protein function results in cilia defects and compromised intraflagellar transport

    Oliver E. Blacque;Michael J. Reardon;Chunmei Li;Jonathan McCarthy

  • MKS and NPHP modules cooperate to establish basal body/transition zone membrane associations and ciliary gate function during ciliogenesis

    Corey L. Williams;Chunmei Li;Katarzyna Kida;Peter N. Inglis

  • Mutations in a member of the Ras superfamily of small GTP-binding proteins causes Bardet-Biedl syndrome.

    Yanli Fan;Muneer A Esmail;Stephen J Ansley;Oliver E Blacque

  • Functional Genomics of the Cilium, a Sensory Organelle

    Oliver E. Blacque;Elliot A. Perens;Keith A. Boroevich;Peter N. Inglis

  • An siRNA-based functional genomics screen for the identification of regulators of ciliogenesis and ciliopathy genes

    Gabrielle Wheway;Miriam Schmidts;Dorus A. Mans;Katarzyna Szymanska

  • An organelle-specific protein landscape identifies novel diseases and molecular mechanisms

    Boldt K;van Reeuwijk J;Lu Q;Koutroumpas K

  • TMEM237 Is Mutated in Individuals with a Joubert Syndrome Related Disorder and Expands the Role of the TMEM Family at the Ciliary Transition Zone

    Lijia Huang;Katarzyna Szymanska;Victor L. Jensen;Andreas R. Janecke

  • Mechanism of transport of IFT particles in C. elegans cilia by the concerted action of kinesin-II and OSM-3 motors

    Xiaoyu Pan;Guangshuo Ou;Gul Civelekoglu-Scholey;Oliver E. Blacque

  • Bardet-Biedl syndrome: an emerging pathomechanism of intracellular transport.

    O. E. Blacque;M. R. Leroux

  • Joubert syndrome Arl13b functions at ciliary membranes and stabilizes protein transport in Caenorhabditis elegans

    Sebiha Cevik;Yuji Hori;Oktay I. Kaplan;Katarzyna Kida

  • Formation of the transition zone by Mks5/Rpgrip1L establishes a ciliary zone of exclusion (CIZE) that compartmentalises ciliary signalling proteins and controls PIP2 ciliary abundance.

    Victor L Jensen;Chunmei Li;Rachel V Bowie;Lara Clarke

  • Sensory Ciliogenesis in Caenorhabditis elegans: Assignment of IFT Components into Distinct Modules Based on Transport and Phenotypic Profiles

    Guangshuo Ou;Makato Koga;Oliver E. Blacque;Oliver E. Blacque;Takashi Murayama

  • TMEM107 recruits ciliopathy proteins to subdomains of the ciliary transition zone and causes Joubert syndrome

    Nils J. Lambacher;Ange-Line Bruel;Teunis J. P. van Dam;Katarzyna Szymańska

  • Evidence for a Direct Interaction between the Tumor Suppressor Serpin, Maspin, and Types I and III Collagen

    Oliver E. Blacque;D. Margaret Worrall

  • Identification of Tubulin Deglutamylase among Caenorhabditis elegans and Mammalian Cytosolic Carboxypeptidases (CCPs)

    Yoshishige Kimura;Nobuya Kurabe;Koji Ikegami;Koji Tsutsumi

  • MKS5 and CEP290 Dependent Assembly Pathway of the Ciliary Transition Zone

    Chunmei Li;Victor L. Jensen;Kwangjin Park;Julie Kennedy

Frequent Co-Authors

Michel R. Leroux
Michel R. Leroux Simon Fraser University
marius ueffing
marius ueffing University of Tübingen
Colin A. Johnson
Colin A. Johnson University of Leeds
Ronald Roepman
Ronald Roepman Radboud University
Philip L. Beales
Philip L. Beales University College London
Nicholas Katsanis
Nicholas Katsanis Galatea Bio Inc
Hannie Kremer
Hannie Kremer Radboud University
Bradley K. Yoder
Bradley K. Yoder University of Alabama at Birmingham
Rachel H. Giles
Rachel H. Giles Utrecht University
Martijn A. Huynen
Martijn A. Huynen Radboud University Medical Center

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