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Neeltje A. Kootstra

Neeltje A. Kootstra

D-Index & Metrics

Microbiology

D-Index
57
Citations
16022
World Ranking
3532
National Ranking
136

Overview

Neeltje A. Kootstra is affiliated with the University of Amsterdam in the Netherlands. Their research primarily resides in the fields of Medicine and Immunology and Microbiology, with significant contributions to subfields such as Infectious Diseases, Virology, Immunology, Epidemiology, and Emergency Medicine.

The scientist's work covers various topics including HIV Research and Treatment, SARS-CoV-2 and COVID-19 Research, COVID-19 Clinical Research Studies, HIV/AIDS Research and Interventions, HIV-related health complications and treatments, Immunotherapy and Immune Responses, and Hepatitis B Virus Studies.

Kootstra has coauthored numerous publications with frequent collaborators such as Marit J. van Gils, Peter Reiss, Abraham Goorhuis, Ferdinand W.N.M. Wit, and Marc van der Valk.

Key recent papers include:

  • Potent neutralizing antibodies from COVID-19 patients define multiple targets of vulnerability, 2020, Science
  • Afucosylated IgG characterizes enveloped viral responses and correlates with COVID-19 severity, 2020, Science
  • HIV-associated gut dysbiosis is independent of sexual practice and correlates with noncommunicable diseases, 2020, Nature Communications
  • Potent neutralizing antibodies from COVID-19 patients define multiple targets of vulnerability, 2020, bioRxiv (Cold Spring Harbor Laboratory)
  • Immunogenicity and Reactogenicity of Vaccine Boosters after Ad26.COV2.S Priming, 2022, New England Journal of Medicine

The scientist frequently publishes in venues such as bioRxiv (Cold Spring Harbor Laboratory), The Journal of Infectious Diseases, Frontiers in Immunology, Clinical Infectious Diseases, and Nature Communications.

Best Publications

  • Biological phenotype of human immunodeficiency virus type 1 clones at different stages of infection: progression of disease is associated with a shift from monocytotropic to T-cell-tropic virus population.

    H Schuitemaker;M Koot;N A Kootstra;M W Dercksen

  • Phenotype-associated sequence variation in the third variable domain of the human immunodeficiency virus type 1 gp120 molecule.

    R A Fouchier;M Groenink;N A Kootstra;M Tersmette

  • Cross-sectional comparison of the prevalence of age-associated comorbidities and their risk factors between HIV-infected and uninfected individuals: the AGEhIV Cohort Study

    Judith Schouten;Ferdinand W. Wit;Ineke G. Stolte;Neeltje A. Kootstra

  • Macrophage-tropic variants initiate human immunodeficiency virus type 1 infection after sexual, parenteral, and vertical transmission.

    A B van't Wout;N A Kootstra;G A Mulder-Kampinga;N Albrecht-van Lent

  • Genetic programs expressed in resting and IL-4 alternatively activated mouse and human macrophages: similarities and differences

    Fernando O. Martinez;Laura Helming;Ronny Milde;Audrey Varin

  • Monocytotropic human immunodeficiency virus type 1 (HIV-1) variants detectable in all stages of HIV-1 infection lack T-cell line tropism and syncytium-inducing ability in primary T-cell culture.

    H. Schuitemaker;N. A. Kootstra;R. E. Y. De Goede;F. De Wolf

  • Gene Therapy with Viral Vectors

    Neeltje A. Kootstra;Inder M. Verma

  • Afucosylated IgG characterizes enveloped viral responses and correlates with COVID-19 severity.

    Mads Delbo Larsen;Erik L. de Graaf;Myrthe E. Sonneveld;H. Rosina Plomp

  • Delivery of the Cre recombinase by a self-deleting lentiviral vector: efficient gene targeting in vivo.

    Alexander Pfeifer;Eugene P. Brandon;Neeltje Kootstra;Fred H. Gage

  • Safety, tolerability, and antiviral effect of RG-101 in patients with chronic hepatitis C : A phase 1B, double-blind, randomised controlled trial

    Meike H van der Ree;J Marleen de Vree;Femke Stelma;Sophie Willemse

  • Proliferation-dependent HIV-1 infection of monocytes occurs during differentiation into macrophages.

    Hanneke Schuitemaker;Neeltje A. Kootstra;Marco H. G. M. Koppelman;Sylvia M. Bruisten

  • Abrogation of postentry restriction of HIV-1-based lentiviral vector transduction in simian cells

    Neeltje A. Kootstra;Carsten Münk;Nina Tonnu;Nathaniel R. Landau

  • HIV-associated gut dysbiosis is independent of sexual practice and correlates with noncommunicable diseases.

    I. Vujkovic-Cvijin;O. Sortino;E. Verheij;J. Sklar

  • Relation between Changes in Cellular Load, Evolution of Viral Phenotype, and the Clonal Composition of Virus Populations in the Course of Human Immunodeficiency Virus Type 1 Infection

    M. Koot;A. B. van 't Wout;N. A. Kootstra;R. E. Y. de Goede

  • The Role of Macrophages in HIV-1 Persistence and Pathogenesis.

    Zita Kruize;Neeltje A. Kootstra

  • Analysis of the Temporal Relationship between Human Immunodeficiency Virus Type 1 Quasispecies in Sequential Blood Samples and Various Organs Obtained at Autopsy

    van 't A.B. Wout;L.J. Ran;C.L. Kuiken;N.A. Kootstra

  • Immunogenicity and Reactogenicity of Vaccine Boosters after Ad26.COV2.S Priming

    Unknown

  • Design and crystal structure of a native-like HIV-1 envelope trimer that engages multiple broadly neutralizing antibody precursors in vivo.

    Max Medina-Ramírez;Fernando Garces;Amelia Escolano;Patrick Skog

  • Miravirsen dosing in chronic hepatitis C patients results in decreased microRNA‐122 levels without affecting other microRNAs in plasma

    M. H. van der Ree;A. J. van der Meer;A. C. van Nuenen;J. de Bruijne

  • Receptor usage dictates HIV-1 restriction by human TRIM5α in dendritic cell subsets

    Carla M. S. Ribeiro;Ramin Sarrami-Forooshani;Laurentia C. Setiawan;Esther M. Zijlstra-Willems

  • The Effect of Trim5 Polymorphisms on the Clinical Course of HIV-1 Infection

    Daniëlle van Manen;Maarten A. N Rits;Corrine Beugeling;Karel van Dort

  • Shear stress sustains atheroprotective endothelial KLF2 expression more potently than statins through mRNA stabilization

    Johannes V van Thienen;Joost O Fledderus;Rob J Dekker;Jakub Rohlena

  • Hepatitis B Virus Pregenomic RNA Is Present in Virions in Plasma and Is Associated With a Response to Pegylated Interferon Alfa-2a and Nucleos(t)ide Analogues

    Louis Jansen;Neeltje A. Kootstra;Karel A. van Dort;R. Bart Takkenberg

  • Lack of T Cell Dysfunction and Programmed Cell Death in Human Immunodeficiency Virus Type 1-Infected Chimpanzees Correlates with Absence of Monocytotropic Variants

    Hanneke Schuitemaker;Linde Meyaard;Neeltje A. Kootstra;Rob Dubbes

  • Productive HIV-1 infection of macrophages restricted to the cell fraction with proliferative capacity.

    H. Schuitemaker;N. A. Kootstra;R. A. M. Fouchier;B. Hooibrink

Frequent Co-Authors

Hanneke Schuitemaker
Hanneke Schuitemaker Valneva (Austria)
Peter Reiss
Peter Reiss University of Amsterdam
Maria Prins
Maria Prins University of Amsterdam
Rogier W. Sanders
Rogier W. Sanders University of Amsterdam
Frank Miedema
Frank Miedema Utrecht University
Hans L. Zaaijer
Hans L. Zaaijer University of Amsterdam
Caroline Sabin
Caroline Sabin University College London
Ben Berkhout
Ben Berkhout University of Amsterdam
Alan Winston
Alan Winston Imperial College London
Claudio Franceschi
Claudio Franceschi University of Bologna

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