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D-Index & Metrics

Biology and Biochemistry

D-Index
54
Citations
11165
World Ranking
15572
National Ranking
6492

Overview

Marianna Sikorska is affiliated with the National Academies of Sciences, Engineering, and Medicine in the United States. Their research primarily focuses on biochemistry, genetics, and molecular biology, with contributions spanning several subfields including molecular biology, organic chemistry, biochemistry, developmental neuroscience, and clinical biochemistry.

The scientist's work extensively covers topics related to coenzyme Q10 studies and effects, free radicals and antioxidants, biochemical acid research studies, mitochondrial function and pathology, anesthesia and neurotoxicity research, metabolism, and genetic disorders, as well as mechanisms and treatments related to Parkinson's disease.

Among recent publications authored or coauthored by Marianna Sikorska are:

  • Ubisol-Q10, a Nanomicellar and Water-Dispersible Formulation of Coenzyme-Q10 as a Potential Treatment for Alzheimer's and Parkinson's Disease, 2021, Antioxidants
  • Effects of Tolerance-Induced Preconditioning on Mitochondrial Biogenesis in Undifferentiated and Differentiated Neuronal Cells, 2022, Frontiers in Bioscience-Landmark
  • Correction to: Orally delivered water soluble coenzyme Q10 (Ubisol-Q10) blocks on-going neurodegeneration in rats exposed to paraquat: potential for therapeutic application in Parkinson's disease, 2021, BMC Neuroscience

Frequent co-authors collaborating with Sikorska include Jagdeep K. Sandhu, Jerome Cohen, Siyaram Pandey, Darcy Wear, and Caleb Vegh.

The researcher has published in several venues, notably:

  • Antioxidants
  • Frontiers in Bioscience-Landmark
  • BMC Neuroscience

The body of work concentrating on the biochemical and molecular mechanisms of neurodegenerative diseases integrates molecular biology approaches with clinical biochemistry insights. Their research on coenzyme Q10 formulation aims to explore therapeutic potentials in neurodegenerative conditions such as Alzheimer's and Parkinson's diseases, particularly focusing on mitochondrial function and neuroprotection.

Best Publications

  • Apoptotic death in epithelial cells: cleavage of DNA to 300 and/or 50 kb fragments prior to or in the absence of internucleosomal fragmentation.

    F. Oberhammer;J.W. Wilson;C. Dive;I.D. Morris

  • Active cell death induced by the anti-estrogens tamoxifen and ICI 164 384 in human mammary carcinoma cells (MCF-7) in culture: the role of autophagy†

    Wilfried Bursch;Adolf Ellinger;Harald Kienzl;Ladislaus Török

  • Topoisomerase II-reactive chemotherapeutic drugs induce apoptosis in thymocytes.

    P R Walker;C Smith;T Youdale;J Leblanc

  • Role of Sox2 in the development of the mouse neocortex

    Mahmud Bani-Yaghoub;Roger G. Tremblay;Joy X. Lei;Dongling Zhang

  • The regulation of cell proliferation by calcium and cyclic AMP.

    J. F. Whitfield;A. L. Boynton;J. P. Macmanus;M. Sikorska

  • Periodicity of DNA folding in higher order chromatin structures.

    J. Filipski;J. Leblanc;T. Youdale;M. Sikorska

  • Differentiation of mouse Neuro 2A cells into dopamine neurons

    Roger G. Tremblay;Marianna Sikorska;Jagdeep K. Sandhu;Jagdeep K. Sandhu;Patricia Lanthier

  • Paraquat induces oxidative stress and neuronal cell death; neuroprotection by water-soluble Coenzyme Q10.

    S McCarthy;M Somayajulu;M Sikorska;H Borowy-Borowski

  • The roles of calcium and cyclic AMP in cell proliferation.

    J. F. Whitfield;A. L. Boynton;J. P. MacManus;R. H. Rixon

  • Sequential DNA Methylation of the Nanog and Oct-4 Upstream Regions in Human NT2 Cells during Neuronal Differentiation

    Paromita Deb-Rinker;Dao Ly;Anna Jezierski;Marianna Sikorska

  • Effects of aluminum and other cations on the structure of brain and liver chromatin.

    P R Walker;J LeBlanc;M Sikorska

  • Endonuclease Activities Associated with High Molecular Weight and Internucleosomal DNA Fragmentation in Apoptosis

    Walker Pr;Weaver Vm;Lach B;LeBlanc J

  • Role of mitochondria in neuronal cell death induced by oxidative stress; neuroprotection by Coenzyme Q10.

    M. Somayajulu;S. McCarthy;M. Hung;M. Sikorska

  • Immunohistochemical analysis of Bcl-2, Bcl-X, Mcl-1, and Bax in tumors of central and peripheral nervous system origin.

    S Krajewski;M Krajewska;J Ehrmann;M Sikorska

  • Measurement of apoptosis by DNA fragmentation.

    Demetrius Matassov;Terri Kagan;Julie Leblanc;Marianna Sikorska

  • The direct measurement of protein kinase C (PKC) activity in isolated membranes using a selective peptide substrate

    Balu R. Chakravarthy;Alexandra Bussey;James F. Whitfield;Marianna Sikorska

  • Degradation of nuclear matrix and DNA cleavage in apoptotic thymocytes

    V.M. Weaver;C.E. Carson;P.R. Walker;N. Chaly

  • SATB1 Cleavage by Caspase 6 Disrupts PDZ Domain-Mediated Dimerization, Causing Detachment from Chromatin Early in T-Cell Apoptosis

    Sanjeev Galande;Liliane A. Dickinson;I. Saira Mian;Marianna Sikorska

  • Relationship between Apoptosis and the Cell Cycle in Lymphocytes: Roles of Protein Kinase C, Tyrosine Phosphorylation, and AP1

    Walker Pr;Kwast-Welfeld J;Gourdeau H;Leblanc J

  • Role of proteolysis in apoptosis: involvement of serine proteases in internucleosomal DNA fragmentation in immature thymocytes

    V M Weaver;B Lach;P R Walker;M Sikorska

Frequent Co-Authors

James F. Whitfield
James F. Whitfield National Academies of Sciences, Engineering, and Medicine
John P. MacManus
John P. MacManus National Academies of Sciences, Engineering, and Medicine
Abdellah Ajji
Abdellah Ajji Polytechnique Montréal
Valerie M. Weaver
Valerie M. Weaver University of California, San Francisco
Benjamin K. Tsang
Benjamin K. Tsang Ottawa Hospital Research Institute
Yau-Huei Wei
Yau-Huei Wei Changhua Christian Hospital
Terumi Kohwi-Shigematsu
Terumi Kohwi-Shigematsu Lawrence Berkeley National Laboratory
Mark A. Tarnopolsky
Mark A. Tarnopolsky McMaster University
David Simon
David Simon Beth Israel Deaconess Medical Center
Stefan M. Pulst
Stefan M. Pulst University of Utah

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