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Neuroscience

D-Index
50
Citations
14241
World Ranking
5649
National Ranking
2503

Overview

M. Margarita Behrens is affiliated with the Salk Institute for Biological Studies in the United States. Their research primarily falls within the broad field of Biochemistry, Genetics and Molecular Biology, with a focus on several subfields including Molecular Biology, Neurology, Genetics, Developmental Neuroscience, and Cognitive Neuroscience.

The scientist's work covers a range of topics, notably in Single-cell and spatial transcriptomics, Epigenetics and DNA Methylation, Genomics and Chromatin Dynamics, RNA Research and Splicing, Neuroinflammation and Neurodegeneration Mechanisms, Gene Regulatory Network Analysis, and Genetics and Neurodevelopmental Disorders.

Frequent publication venues for their research include bioRxiv (Cold Spring Harbor Laboratory), Nature, Cell Genomics, Science, and Neuron.

Among recent papers, notable publications are:

  • Comparative cellular analysis of motor cortex in human, marmoset and mouse (2021, Nature)
  • A multimodal cell census and atlas of the mammalian primary motor cortex (2021, Nature)
  • Comprehensive analysis of single cell ATAC-seq data with SnapATAC (2021, Nature Communications)
  • A transcriptomic and epigenomic cell atlas of the mouse primary motor cortex (2021, Nature)
  • DNA methylation atlas of the mouse brain at single-cell resolution (2021, Nature)

M. Margarita Behrens has collaborated frequently with various co-authors, including Joseph R. Ecker, Hanqing Liu, Joseph R. Nery, Bing Ren, and Julia Osteen.

Best Publications

  • Global Epigenomic Reconfiguration During Mammalian Brain Development

    Ryan Lister;Ryan Lister;Eran A. Mukamel;Joseph R. Nery;Mark Urich

  • Interleukin-1β Enhances NMDA Receptor-Mediated Intracellular Calcium Increase through Activation of the Src Family of Kinases

    Barbara Viviani;S. Bartesaghi;F. Gardoni;A. Vezzani

  • Comparative cellular analysis of motor cortex in human, marmoset and mouse

    Trygve E. Bakken;Nikolas L. Jorstad;Qiwen Hu;Blue B. Lake

  • Ketamine-induced loss of phenotype of fast-spiking interneurons is mediated by NADPH-oxidase

    M. Margarita Behrens;Sameh S. Ali;Diep N. Dao;Jacinta Lucero

  • Single-cell methylomes identify neuronal subtypes and regulatory elements in mammalian cortex

    Chongyuan Luo;Christopher L. Keown;Laurie Kurihara;Jingtian Zhou;Jingtian Zhou

  • A loss of parvalbumin-containing interneurons is associated with diminished oscillatory activity in an animal model of schizophrenia

    Daniel J. Lodge;Margarita M. Behrens;Anthony A. Grace

  • Interleukin-1β Contributes to the Generation of Experimental Febrile Seizures

    Celine Dubé;Annamaria Vezzani;Marga Behrens;Tamas Bartfai

  • Comprehensive analysis of single cell ATAC-seq data with SnapATAC.

    Rongxin Fang;Rongxin Fang;Sebastian Preissl;Yang Li;Xiaomeng Hou

  • A Specific Role for NR2A-Containing NMDA Receptors in the Maintenance of Parvalbumin and GAD67 Immunoreactivity in Cultured Interneurons

    Jefferson W. Kinney;Christopher N. Davis;Iustin Tabarean;Bruno Conti

  • Zinc-induced cortical neuronal death: contribution of energy failure attributable to loss of NAD(+) and inhibition of glycolysis.

    Christian T. Sheline;M. Margarita Behrens;Dennis W. Choi

  • A transcriptomic and epigenomic cell atlas of the mouse primary motor cortex.

    Zizhen Yao;Hanqing Liu;Fangming Xie;Stephan Fischer

  • An ultra high-throughput method for single-cell joint analysis of open chromatin and transcriptome.

    Chenxu Zhu;Miao Yu;Hui Huang;Hui Huang;Ivan Juric

  • Joint profiling of histone modifications and transcriptome in single cells from mouse brain.

    Chenxu Zhu;Yanxiao Zhang;Yang Eric Li;Jacinta Lucero

  • DNA methylation atlas of the mouse brain at single-cell resolution.

    Hanqing Liu;Hanqing Liu;Jingtian Zhou;Jingtian Zhou;Wei Tian;Chongyuan Luo;Chongyuan Luo

  • Interleukin-6 Mediates the Increase in NADPH-Oxidase in the Ketamine Model of Schizophrenia

    M. Margarita Behrens;Sameh S. Ali;Laura L. Dugan

  • Metabotropic Glutamate Receptor 1-Induced Upregulation of NMDA Receptor Current: Mediation through the Pyk2/Src-Family Kinase Pathway in Cortical Neurons

    Valérie Heidinger;Pat Manzerra;Xue Qing Wang;Uta Strasser

  • Behavioral and neurochemical consequences of cortical oxidative stress on parvalbumin-interneuron maturation in rodent models of schizophrenia.

    Susan B. Powell;Terrence J. Sejnowski;Terrence J. Sejnowski;M. Margarita Behrens

  • Does schizophrenia arise from oxidative dysregulation of parvalbumin-interneurons in the developing cortex?

    M. Margarita Behrens;Terrence J. Sejnowski;Terrence J. Sejnowski

  • Single nucleus multi-omics identifies human cortical cell regulatory genome diversity

    Unknown

  • IL-6 Mediated Degeneration of Forebrain GABAergic Interneurons and Cognitive Impairment in Aged Mice through Activation of Neuronal NADPH Oxidase

    Laura L. Dugan;Sameh S. Ali;Grigoriy Shekhtman;Amanda J. Roberts

  • An atlas of gene regulatory elements in adult mouse cerebrum.

    Yang Eric Li;Sebastian Preissl;Xiaomeng Hou;Ziyang Zhang

  • DNA Methylation Atlas of the Mouse Brain at Single-Cell Resolution

    Hanqing Liu;Hanqing Liu;Jingtian Zhou;Jingtian Zhou;Wei Tian;Chongyuan Luo;Chongyuan Luo

Frequent Co-Authors

Bing Ren
Bing Ren New York Genome Center
Joseph R. Nery
Joseph R. Nery Salk Institute for Biological Studies
Terrence J. Sejnowski
Terrence J. Sejnowski Salk Institute for Biological Studies
Tamas Bartfai
Tamas Bartfai Stockholm University
Aviv Regev
Aviv Regev Genentech
Dennis W. Choi
Dennis W. Choi Stony Brook University
Zizhen Yao
Zizhen Yao Allen Institute for Brain Science
Steven A. McCarroll
Steven A. McCarroll Harvard University
Peter V. Kharchenko
Peter V. Kharchenko Harvard University
Michael Hawrylycz
Michael Hawrylycz Allen Institute for Brain Science

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