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Genetics

D-Index
60
Citations
21043
World Ranking
3114
National Ranking
1360

Overview

Zizhen Yao is affiliated with the Allen Institute for Brain Science in the United States. Their research primarily focuses on neuroscience and molecular biology with significant contributions to biochemistry, genetics, and molecular biology.

The scientist's work spans several subfields, including molecular biology, neurology, cognitive neuroscience, biophysics, and cellular and molecular neuroscience. The main topics covered in their research include single-cell and spatial transcriptomics, neuroinflammation and neurodegeneration mechanisms, neural dynamics and brain function, cell image analysis techniques, RNA research and splicing, neuroscience and neuropharmacology research, and immune cells in cancer.

Recent published papers by Zizhen Yao include:

  • A taxonomy of transcriptomic cell types across the isocortex and hippocampal formation (2021, Cell)
  • A high-resolution transcriptomic and spatial atlas of cell types in the whole mouse brain (2023, Nature)
  • Comparative cellular analysis of motor cortex in human, marmoset and mouse (2021, Nature)
  • A multimodal cell census and atlas of the mammalian primary motor cortex (2021, Nature)
  • Integrated Morphoelectric and Transcriptomic Classification of Cortical GABAergic Cells (2020, Cell)

The frequent co-authors collaborating with Zizhen Yao include:

  • Hongkui Zeng
  • Bosiljka Tasic
  • Kimberly A. Smith
  • Jeff Goldy
  • Nick Dee

Zizhen Yao publishes extensively in various scientific journals, with the most frequent publication venues being:

  • bioRxiv (Cold Spring Harbor Laboratory)
  • Nature
  • Cell Reports
  • Cell
  • Science

Best Publications

  • Shared and distinct transcriptomic cell types across neocortical areas

    Bosiljka Tasic;Zizhen Yao;Lucas T. Graybuck;Kimberly A. Smith

  • Adult mouse cortical cell taxonomy revealed by single cell transcriptomics

    Bosiljka Tasic;Vilas Menon;Thuc Nghi Nguyen;Tae Kyung Kim

  • Conserved cell types with divergent features in human versus mouse cortex.

    Rebecca D. Hodge;Trygve E. Bakken;Jeremy A. Miller;Kimberly A. Smith

  • Single-cell profiling of the developing mouse brain and spinal cord with split-pool barcoding

    Alexander B. Rosenberg;Charles M. Roco;Richard A. Muscat;Anna Kuchina

  • A taxonomy of transcriptomic cell types across the isocortex and hippocampal formation.

    Zizhen Yao;Cindy T.J. van Velthoven;Thuc Nghi Nguyen;Jeff Goldy

  • A Suite of Transgenic Driver and Reporter Mouse Lines with Enhanced Brain-Cell-Type Targeting and Functionality

    Tanya L. Daigle;Linda Madisen;Travis A. Hage;Matthew T. Valley

  • Comparative cellular analysis of motor cortex in human, marmoset and mouse

    Trygve E. Bakken;Nikolas L. Jorstad;Qiwen Hu;Blue B. Lake

  • Canonical Genetic Signatures of the Adult Human Brain

    Michael Hawrylycz;Jeremy A. Miller;Vilas Menon;David Feng

  • Single-nucleus and single-cell transcriptomes compared in matched cortical cell types.

    Trygve E. Bakken;Rebecca D. Hodge;Jeremy A. Miller;Zizhen Yao

  • Genome-wide MyoD Binding in Skeletal Muscle Cells: A Potential for Broad Cellular Reprogramming

    Yi Cao;Zizhen Yao;Deepayan Sarkar;Michael Lawrence

  • Integrated Morphoelectric and Transcriptomic Classification of Cortical GABAergic Cells.

    Nathan W. Gouwens;Staci A. Sorensen;Fahimeh Baftizadeh;Agata Budzillo

  • Spatially resolved cell atlas of the mouse primary motor cortex by MERFISH.

    Meng Zhang;Meng Zhang;Stephen W. Eichhorn;Stephen W. Eichhorn;Brian Zingg;Brian Zingg;Zizhen Yao

  • DUX4 Activates Germline Genes, Retroelements, and Immune Mediators: Implications for Facioscapulohumeral Dystrophy

    Linda N. Geng;Zizhen Yao;Lauren Snider;Abraham P. Fong

  • CMfinder---a covariance model based RNA motif finding algorithm

    Zizhen Yao;Zasha Weinberg;Walter L. Ruzzo

  • Morphological diversity of single neurons in molecularly defined cell types

    Hanchuan Peng;Hanchuan Peng;Peng Xie;Lijuan Liu;Xiuli Kuang

  • Identification of 22 candidate structured RNAs in bacteria using the CMfinder comparative genomics pipeline.

    Zasha Weinberg;Jeffrey E. Barrick;Zizhen Yao;Adam Roth

  • Phenotypic variation of transcriptomic cell types in mouse motor cortex

    Federico Scala;Dmitry Kobak;Matteo Bernabucci;Yves Bernaerts

  • A Taxonomy of Transcriptomic Cell Types Across the Isocortex and Hippocampal Formation

    Zizhen Yao;Thuc Nghi Nguyen;Cindy T. J. van Velthoven;Jeff Goldy

  • A multimodal cell census and atlas of the mammalian primary motor cortex

    Ricky Adkins;Andrew Aldridge;Shona Allen

  • CMfinder—acovariancemodelbasedRNA motiffinding algorithm

    Zizhen Yao;Zasha Weinberg;Walter L. Ruzzo

Frequent Co-Authors

Bosiljka Tasic
Bosiljka Tasic Allen Institute for Brain Science
Hongkui Zeng
Hongkui Zeng Allen Institute for Brain Science
Kimberly A. Smith
Kimberly A. Smith Allen Institute for Brain Science
Stephen J. Tapscott
Stephen J. Tapscott Fred Hutchinson Cancer Research Center
Michael Hawrylycz
Michael Hawrylycz Allen Institute for Brain Science
Ed S. Lein
Ed S. Lein University of Washington
Walter L. Ruzzo
Walter L. Ruzzo University of Washington
Christof Koch
Christof Koch Allen Institute for Brain Science
Jonathan T. Ting
Jonathan T. Ting Allen Institute for Brain Science
Songlin Ding
Songlin Ding RMIT University

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