Linda C. McPhail

Research.com Recognitions

• 1997 - Fellow of the American Association for the Advancement of Science (AAAS)

Overview

Best Publications

• A potential second messenger role for unsaturated fatty acids: activation of Ca2+-dependent protein kinase.

  Linda C. McPhail;Christine C. Clayton;Ralph Snyderman

  859
  Citations

• Activation of the respiratory burst enzyme from human neutrophils in a cell-free system. Evidence for a soluble cofactor.

  L C McPhail;P S Shirley;C C Clayton;R Snyderman

  454
  Citations

• Phorbol myristate acetate mediates redistribution of protein kinase C in human neutrophils: potential role in the activation of the respiratory burst enzyme.

  M Wolfson;L C McPhail;V N Nasrallah;R Snyderman

  393
  Citations

• Activation of the respiratory burst enzyme in human polymorphonuclear leukocytes by chemoattractants and other soluble stimuli. Evidence that the same oxidase is activated by different transductional mechanisms.

  Linda C. Mcphail;Ralph Snyderman

  314
  Citations

• The NADPH oxidase of human polymorphonuclear leukocytes : evidence for regulation by multiple signals

  L C McPhail;C C Clayton;R Snyderman

  305
  Citations

• Pseudomonas aeruginosa Psl polysaccharide reduces neutrophil phagocytosis and the oxidative response by limiting complement-mediated opsonization.

  Meenu Mishra;Matthew S. Byrd;Susan Sergeant;Abul K. Azad

  300
  Citations

• Choline-linked Phosphoglycerides A SOURCE OF PHOSPHATIDIC ACID AND DIGLYCERIDES IN STIMULATED NEUTROPHILS*

  D E Agwu;L C McPhail;M C Chabot;L W Daniel

  295
  Citations

• Role of protein kinases in stimulation of human polymorphonuclear leukocyte oxidative metabolism by various agonists. Differential effects of a novel protein kinase inhibitor.

  C Gerard;L C McPhail;A Marfat;N P Stimler-Gerard

  294
  Citations

• Phorbol myristate acetate induces neutrophil NADPH-oxidase activity by two separate signal transduction pathways: dependent or independent of phosphatidylinositol 3-kinase.

  Anna Karlsson;Jennifer B. Nixon;Linda C. McPhail

  279
  Citations

• Phosphatidic acid as a second messenger in human polymorphonuclear leukocytes. Effects on activation of NADPH oxidase.

  D E Agwu;L C McPhail;S Sozzani;D A Bass

  234
  Citations

• Phosphatidic Acid-mediated Phosphorylation of the NADPH Oxidase Component p47-phox EVIDENCE THAT PHOSPHATIDIC ACID MAY ACTIVATE A NOVEL PROTEIN KINASE

  Kristin A. Waite;Reidar Wallin;Diane Qualliotine-Mann;Linda C. McPhail

  194
  Citations

• Oxidative Metabolism of the Human Eosinophil

  Lawrence R. DeChatelet;Pamela S. Shirley;Linda C. McPhail;Carolyn C. Huntley

  181
  Citations

• Creation of a genetic system for analysis of the phagocyte respiratory burst: high-level reconstitution of the NADPH oxidase in a nonhematopoietic system

  Marianne O. Price;Linda C. McPhail;J. David Lambeth;Chang-Hoon Han

  176
  Citations

• Chemoattractant-elicited alterations of cAMP levels in human polymorphonuclear leukocytes require a Ca2+-dependent mechanism which is independent of transmembrane activation of adenylate cyclase.

  M W Verghese;K Fox;L C McPhail;R Snyderman

  170
  Citations

• Phosphatidic acid and diacylglycerol directly activate NADPH oxidase by interacting with enzyme components.

  Anita Palicz;Anita Palicz;Thomas R. Foubert;Algirdas J. Jesaitis;Laszlo Marodi

  166
  Citations

• Fueling the flame: bioenergy couples metabolism and inflammation

  Tie Fu Liu;Candice M. Brown;Mohamed El Gazzar;Linda McPhail

  153
  Citations

• Propranolol, a phosphatidate phosphohydrolase inhibitor, also inhibits protein kinase C.

  Silvano Sozzani;David E. Agwu;Charles E. McCall;Joseph T. O'Flaherty

  152
  Citations

• Superoxide Dismutase Activity in Leukocytes

  Lawrence R. Dechatelet;Charles E. McCall;Linda C. McPhail;Richard B. Johnston

  149
  Citations

• Priming of the respiratory burst of neutrophils by diacylglycerol. Independence from activation or translocation of protein kinase C.

  D A Bass;C Gerard;P Olbrantz;J Wilson

  148
  Citations

• Redistribution of protein kinase C activity in human monocytes: correlation with activation of the respiratory burst.

  M A Myers;L C McPhail;R Snyderman

  145
  Citations