Julian C. Knight

Overview

Best Publications

• Large-scale cis- and trans-eQTL analyses identify thousands of genetic loci and polygenic scores that regulate blood gene expression

  Urmo Võsa;Annique Claringbould;Annique Claringbould;Harm-Jan Westra;Marc Jan Bonder

  2003
  Citations

• Systematic identification of trans eQTLs as putative drivers of known disease associations

  Harm-Jan Westra;Marjolein J Peters;Tõnu Esko;Hanieh Yaghootkar

  1949
  Citations

• Genetic mechanisms of critical illness in Covid-19.

  E. Pairo-Castineira;E. Pairo-Castineira;S. Clohisey;L. Klaric;A. D. Bretherick

  1445
  Citations

• Single-dose administration and the influence of the timing of the booster dose on immunogenicity and efficacy of ChAdOx1 nCoV-19 (AZD1222) vaccine: a pooled analysis of four randomised trials.

  M Voysey;S A Costa Clemens;S A Madhi;L Y Weckx

  1285
  Citations

• Broad and strong memory CD4 + and CD8 + T cells induced by SARS-CoV-2 in UK convalescent individuals following COVID-19.

  Y Peng;A J Mentzer;G Liu;G Liu;X Yao

  1277
  Citations

• A ChIP-seq defined genome-wide map of vitamin D receptor binding: associations with disease and evolution.

  Sreeram V. Ramagopalan;Andreas Heger;Antonio J. Berlanga;Narelle J. Maugeri

  1101
  Citations

• Genetic association analyses implicate aberrant regulation of innate and adaptive immunity genes in the pathogenesis of systemic lupus erythematosus

  James Bentham;David L. Morris;Deborah S. Cunninghame Graham;Christopher L. Pinder

  1080
  Citations

• Evidence of escape of SARS-CoV-2 variant B.1.351 from natural and vaccine-induced sera.

  D Zhou;W Dejnirattisai;P Supasa;C Liu

  1044
  Citations

• Innate immune activity conditions the effect of regulatory variants upon monocyte gene expression.

  Benjamin P. Fairfax;Peter Humburg;Seiko Makino;Vivek Naranbhai

  904
  Citations

• Major Histocompatibility Complex Genomics and Human Disease

  John Trowsdale;Julian C. Knight

  833
  Citations

• Genomic landscape of the individual host response and outcomes in sepsis: a prospective cohort study

  Emma E Davenport;Katie L Burnham;Jayachandran Radhakrishnan;Peter Humburg

  812
  Citations

• The polygenic and monogenic basis of blood traits and diseases

  Dragana Vuckovic;Erik L. Bao;Parsa Akbari;Caleb A. Lareau

  696
  Citations

• Reduced neutralization of SARS-CoV-2 B.1.617 by vaccine and convalescent serum.

  C Liu;H M Ginn;W Dejnirattisai;P Supasa

  686
  Citations

• Expression of the Multiple Sclerosis-Associated MHC Class II Allele HLA-DRB1*1501 Is Regulated by Vitamin D

  Sreeram V. Ramagopalan;Narelle J. Maugeri;Lahiru Handunnetthi;Lahiru Handunnetthi;Matthew R. Lincoln;Matthew R. Lincoln

  672
  Citations

• A polymorphism that affects OCT-1 binding to the TNF promoter region is associated with severe malaria.

  Julian C. Knight;Irina Udalova;Adrian V.S. Hill;Brian M. Greenwood

  617
  Citations

• T cell and antibody responses induced by a single dose of ChAdOx1 nCoV-19 (AZD1222) vaccine in a phase 1/2 clinical trial.

  K J Ewer;Barrett;S Belij-Rammerstorfer;H Sharpe

  609
  Citations

• Genetics of gene expression in primary immune cells identifies cell type–specific master regulators and roles of HLA alleles

  Benjamin P Fairfax;Seiko Makino;Jayachandran Radhakrishnan;Katharine Plant

  589
  Citations

• Antibody evasion by the P.1 strain of SARS-CoV-2.

  W Dejnirattisai;D Zhou;P Supasa;C Liu

  576
  Citations

• Genetic mechanisms of critical illness in Covid-19

  Erola Pairo-Castineira;Sara Clohisey;Lucija Klaric;Andrew Bretherick;Andrew Bretherick

  98
  Citations

• Single Dose Administration, And The Influence Of The Timing Of The Booster Dose On Immunogenicity and Efficacy Of ChAdOx1 nCoV-19 (AZD1222) Vaccine (preprint)

  Voysey, Merryn, Costa Clemens, Sue Ann, Madhi, Shabir A.;Weckx, Lily Yin, Folegatti, Pedro M.;Parvinder K. Aley;Angus, Brian John, Baillie, Vicky, Barnabas, Shaun L.

  28
  Citations