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D-Index & Metrics

Biology and Biochemistry

D-Index
69
Citations
18268
World Ranking
7337
National Ranking
3362

Research.com Recognitions

  • 2016 - Fellow of the Indian National Academy of Engineering (INAE)

Overview

John M. Lambert is affiliated with ImmunoGen in the United States. Their research spans multiple fields, primarily Medicine and Earth and Planetary Sciences. The scientist's work involves a range of subfields including Oncology, Anthropology, Space and Planetary Science, Cell Biology, and Ecology.

Their research topics focus on Archaeological Research and Protection, HER2/EGFR in Cancer Research, Monoclonal and Polyclonal Antibodies Research, CAR-T Cell Therapy Research, Pleistocene-Era Hominins and Archaeology, Morphological Variations and Asymmetry, as well as Image Processing and 3D Reconstruction.

Frequent co-authors in their collaborations include Charles Dumontet, Janice M. Reichert, Peter D. Senter, Alain Beck, and Ashley M. Smallwood.

Notable publication venues where John M. Lambert has contributed include the Midcontinental Journal of Archaeology, Nature Reviews Drug Discovery, American Antiquity, Journal of Archaeological Science Reports, and Neuromuscular Disorders.

Selected recent papers by the scientist include:

  • "Antibody-drug conjugates come of age in oncology," 2023, Nature Reviews Drug Discovery
  • "Using 3D Models to Understand the Changing Role of Fluting in Paleoindian Point Technology from Clovis to Dalton," 2022, American Antiquity
  • "A critical review of UAS-based aerial photography and photogrammetry of Cahokia's Grand Plaza," 2022, Journal of Archaeological Science Reports
  • "DMD - BIOMARKERS & OUTCOME MEASURES," 2020, Neuromuscular Disorders
  • "An Intracellular Calcium Signal Activates p70 but Not p90 Ribosomal S6 Kinase in Liver Epithelial Cells," 2021, UNC Libraries

John M. Lambert has been recognized as a Fellow of the Indian National Academy of Engineering (INAE) since 2016.

Best Publications

  • Targeting HER2-Positive Breast Cancer with Trastuzumab-DM1, an Antibody–Cytotoxic Drug Conjugate

    Gail D. Lewis Phillips;Guangmin Li;Debra L. Dugger;Lisa M. Crocker

  • Cytotoxic agents comprising maytansinoids and their therapeutic use

    Ravi J. Chari;Victor S. Goldmacher;John M. Lambert;Walter A. Blattler

  • Ado-trastuzumab Emtansine (T-DM1): An Antibody–Drug Conjugate (ADC) for HER2-Positive Breast Cancer

    John M. Lambert;Ravi V. J. Chari

  • Humanization of murine monoclonal antibodies through variable domain resurfacing

    Michael A. Roguska;Jan T. Pedersen;Christine A. Keddy;Andrew H. Henry

  • Tiam1 mediates Ras activation of Rac by a PI(3)K-independent mechanism

    John M. Lambert;Que T. Lambert;Gary W. Reuther;Angeliki Malliri

  • Structural characterization of the maytansinoid–monoclonal antibody immunoconjugate, huN901–DM1, by mass spectrometry

    Lintao Wang;Godfrey Amphlett;Walter A. Blättler;John M. Lambert

  • ERADICATION OF LARGE COLON TUMOR XENOGRAFTS BY TARGETED DELIVERY OF MAYTANSINOIDS

    C. Liu;B. M. Tadayoni;L. A. Bourret;K. M. Mattocks

  • Drug-conjugated Monoclonal Antibodies for the Treatment of Cancer

    John M Lambert

  • New developments for antibody-drug conjugate-based therapeutic approaches

    Bart Ecg de Goeij;John M Lambert

  • Antibody-Drug Conjugates (ADCs) for Personalized Treatment of Solid Tumors: A Review.

    John M. Lambert;Charles Q. Morris

  • Acid-cleavable compound, use in protein conjugates and drug delivery systems

    Walter A. Blattler;John M. Lambert;Peter D. Senter

  • Antibody-Drug Conjugates for Cancer Treatment.

    John M Lambert;Anna Berkenblit

  • Cantuzumab Mertansine, a Maytansinoid Immunoconjugate Directed to the CanAg Antigen: A Phase I, Pharmacokinetic, and Biologic Correlative Study

    Anthony W. Tolcher;Leonel Ochoa;Lisa A. Hammond;Amita Patnaik

  • The site of action of six different ribosome-inactivating proteins from plants on eukaryotic ribosomes: the RNA N-glycosidase activity of the proteins.

    Yaeta Endo;Kunio Tsurugi;John M. Lambert

  • Addition of sulfhydryl groups to Escherichia coli ribosomes by protein modification with 2-iminothiolane (methyl 4-mercaptobutyrimidate).

    Rodney Jue;John M. Lambert;Leland R. Pierce;Robert R. Traut

  • Disulfide-linked antibody-maytansinoid conjugates: optimization of in vivo activity by varying the steric hindrance at carbon atoms adjacent to the disulfide linkage

    Brenda A. Kellogg;Lisa Garrett;Yelena Kovtun;Katharine C. Lai

  • Purified immunotoxins that are reactive with human lymphoid cells. Monoclonal antibodies conjugated to the ribosome-inactivating proteins gelonin and the pokeweed antiviral proteins.

    J M Lambert;P D Senter;A Yau-Young;W A Blättler

  • Serotherapy of B-cell neoplasms with anti-B4-blocked ricin: a phase I trial of daily bolus infusion

    ML Grossbard;AS Freedman;J Ritz;F Coral

  • Anti-B4-blocked ricin: a phase I trial of 7-day continuous infusion in patients with B-cell neoplasms.

    M L Grossbard;J M Lambert;V S Goldmacher;N L Spector

  • SAR3419: an anti-CD19-Maytansinoid Immunoconjugate for the treatment of B-cell malignancies.

    Veronique Blanc;Anne Bousseau;Anne Caron;Chantal Carrez

Frequent Co-Authors

Victor S. Goldmacher
Victor S. Goldmacher ImmunoGen (United States)
Stuart F. Schlossman
Stuart F. Schlossman Harvard University
Jerome Ritz
Jerome Ritz Harvard University
Peter D. Senter
Peter D. Senter Seattle Genetics (United States)
Norman L. Letvin
Norman L. Letvin Beth Israel Deaconess Medical Center
Lee M. Nadler
Lee M. Nadler Harvard University
Keith A. Reimann
Keith A. Reimann Harvard Medical School
Larry W. Kwak
Larry W. Kwak City Of Hope National Medical Center
Rosemary O'Connor
Rosemary O'Connor University College Cork
Corinne Haioun
Corinne Haioun Paris-Est Créteil University

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