His main research concerns Neuroscience, Degenerative disease, Pathology, Cerebral cortex and Huntington's disease. His research integrates issues of Dementia, Pediatrics, Alzheimer's disease, Neuropathology and Repeated sequence in his study of Degenerative disease. His Pediatrics research includes themes of Nun Study, Braak staging and Gerontology.
His Pathology research integrates issues from Locus coeruleus, Nucleus and Neuron. His Cerebral cortex study incorporates themes from Neurotoxin, Central nervous system, Anatomy and Thalamus. The various areas that John C. Hedreen examines in his Huntington's disease study include Basal ganglia, Striatum, Gene product and Claustrum.
His primary areas of study are Neuroscience, Pathology, Disease, Dementia and Degenerative disease. His research investigates the link between Disease and topics such as Pathological that cross with problems in Corticobasal degeneration and Depression. The study incorporates disciplines such as Alzheimer's disease and Central nervous system disease in addition to Dementia.
His Alzheimer's disease study focuses on Neurofibrillary tangle in particular. He interconnects Huntington's disease, Neurodegeneration and Gene expression in the investigation of issues within Degenerative disease. His Neuropathology study combines topics in areas such as Pediatrics and Juvenile Huntington Disease.
The scientist’s investigation covers issues in Pathology, Neuroscience, Human brain, Neuropathology and Substantia nigra. His study in the field of Corticobasal degeneration, Pathological and Frontotemporal lobar degeneration is also linked to topics like Cytoplasmic inclusion. John C. Hedreen focuses mostly in the field of Neuroscience, narrowing it down to topics relating to Enhancer and, in certain cases, Genome.
His studies examine the connections between Human brain and genetics, as well as such issues in Basal ganglia, with regards to Neuron and Dopaminergic. His work carried out in the field of Neuropathology brings together such families of science as Dystonia, Dystonia Musculorum Deformans, Juvenile Huntington Disease and Midbrain. His Substantia nigra research is multidisciplinary, relying on both Cerebellum, Neurochemical and Hippocampus.
Human brain, Neuroscience, Midbrain, Substantia nigra and Dystonia Musculorum Deformans are his primary areas of study. His research in Human brain intersects with topics in Hippocampal formation, Astrocyte, Temporal cortex and Neuron. In his works, John C. Hedreen conducts interdisciplinary research on Neuroscience and Expression quantitative trait loci.
His studies deal with areas such as Dystonia, Neuropathology, Hippocampus and Cerebellum as well as Midbrain.
This overview was generated by a machine learning system which analysed the scientist’s body of work. If you have any feedback, you can contact us here.
PGC-1α, A Potential Therapeutic Target for Early Intervention in Parkinson’s Disease
Bin Zheng;Zhixiang Liao;Joseph J. Locascio;Kristen A. Lesniak.
Science Translational Medicine (2010)
Evidence for apoptotic cell death in Huntington disease and excitotoxic animal models.
Carlos Portera-Cailliau;John C. Hedreen;Donald L. Price;Vassilis E. Koliatsos.
The Journal of Neuroscience (1995)
Phenotypic characterization of individuals with 30-40 CAG repeats in the Huntington disease (HD) gene reveals HD cases with 36 repeats and apparently normal elderly individuals with 36-39 repeats.
Rubinsztein Dc;Leggo J;Coles R;Almqvist E.
American Journal of Human Genetics (1996)
Topographic analysis of the innervation of the rat neocortex and hippocampus by the basal forebrain cholinergic system.
Michael McKinney;Joseph T. Coyle;John C. Hedreen.
The Journal of Comparative Neurology (1983)
Basal forebrain neurons in the dementia of Parkinson disease
Peter J. Whitehouse;John C. Hedreen;Charles L. White;Donald L. Price.
Annals of Neurology (1983)
A modified histochemical technique to visualize acetylcholinesterase-containing axons.
John C. Hedreen;Sarah J. Bacon;Donald L. Price.
Journal of Histochemistry and Cytochemistry (1985)
Widespread expression of Huntington's disease gene (IT15) protein product
Alan H. Sharp;Scott J. Loev;Gabriele Schilling;Shi Hua Li.
The neuropathology of aminergic nuclei in Alzheimer's disease
R. M. Zweig;C. A. Ross;J. C. Hedreen;C. Steele.
Annals of Neurology (1988)
The Consortium to Establish a Registry for Alzheimer's Disease (CERAD). Part X. Neuropathology Confirmation of the Clinical Diagnosis of Alzheimer's Disease
M. Gearing;S. S. Mirra;J. C. Hedreen;S. M. Sumi.
The pedunculopontine nucleus in Parkinson's disease
R. M. Zweig;W. R. Jankel;J. C. Hedreen;R. Mayeux.
Annals of Neurology (1989)
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