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Computer Science

D-Index
35
Citations
5563
World Ranking
11657
National Ranking
88

Overview

Jens Lagergren is a researcher affiliated with the Royal Institute of Technology in Sweden. Their work spans key areas within Biochemistry, Genetics and Molecular Biology, alongside contributions to Computer Science.

The scientist has authored numerous papers with significant focus on topics such as:

  • Single-cell and spatial transcriptomics
  • Cancer Genomics and Diagnostics
  • Gene expression and cancer classification
  • Genomics and Phylogenetic Studies
  • Bioinformatics and Genomic Networks
  • Bayesian Methods and Mixture Models
  • T-cell and B-cell Immunology

Among recent publications are:

  • Spatial transcriptomics of B cell and T cell receptors reveals lymphocyte clonal dynamics (2023, Science)
  • Clonally heritable gene expression imparts a layer of diversity within cell types (2024, Cell Systems)
  • DeepMP: a deep learning tool to detect DNA base modifications on Nanopore sequencing data (2021, Bioinformatics)
  • Celloscope: a probabilistic model for marker-gene-driven cell type deconvolution in spatial transcriptomics data (2023, Genome Biology)
  • Breast cancer patient-derived whole-tumor cell culture model for efficient drug profiling and treatment response prediction (2022, Proceedings of the National Academy of Sciences)

Lagergren collaborates frequently with a set of co-authors, including:

  • Hosein Toosi
  • Jeff E. Mold
  • Xinsong Chen
  • Johan Hartman
  • Camilla Engblom

Research outputs are commonly published in venues such as:

  • bioRxiv (Cold Spring Harbor Laboratory)
  • arXiv (Cornell University)
  • Bioinformatics
  • Nature Communications
  • PLoS Computational Biology

Their work addresses subfields including Molecular Biology, Cancer Research, Artificial Intelligence, Immunology, and Computer Vision and Pattern Recognition. This interdisciplinary approach highlights integration of computational techniques with molecular and cancer biology research.

Best Publications

  • Easy problems for tree-decomposable graphs

    Stefan Arnborg;Jens Lagergren;Detlef Seese

  • Spatial maps of prostate cancer transcriptomes reveal an unexplored landscape of heterogeneity

    Emelie Berglund;Jonas Maaskola;Niklas Schultz;Stefanie Friedrich

  • On the Hardness of Approximating Max k-Cut and its Dual.

    Viggo Kann;Sanjeev Khanna;Jens Lagergren;Alessandro Panconesi

  • Bayesian gene/species tree reconciliation and orthology analysis using MCMC

    Lars Arvestad;Ann-Charlotte Berglund;Jens Lagergren;Bengt Sennblad

  • Simultaneous Bayesian gene tree reconstruction and reconciliation analysis.

    Örjan Åkerborg;Bengt Sennblad;Lars Arvestad;Jens Lagergren

  • Efficient algorithms for lateral gene transfer problems

    M. T. Hallett;J. Lagergren

  • Simultaneous Identification of Duplications and Lateral Gene Transfers

    Ali Tofigh;Michael Hallett;Jens Lagergren

  • Gene tree reconstruction and orthology analysis based on an integrated model for duplications and sequence evolution

    Lars Arvestad;Ann-Charlotte Berglund;Jens Lagergren;Bengt Sennblad

  • New algorithms for the duplication-loss model

    M. T. Hallett;J. Lagergren

  • Identification of functional clusters of transcription factor binding motifs in genome sequences: the MSCAN algorithm.

    Öjvind Johansson;Wynand Alkema;Wyeth W. Wasserman;Jens Lagergren

  • Genome-wide survey for biologically functional pseudogenes.

    Örjan Per Svensson;Lars Arvestad;Jens Lagergren

  • New probabilistic network models and algorithms for oncogenesis.

    Marcus Hjelm;Mattias Höglund;Jens Lagergren

  • A Bayesian method for analyzing lateral gene transfer.

    Joel Sjöstrand;Joel Sjöstrand;Ali Tofigh;Vincent Daubin;Lars Arvestad;Lars Arvestad

  • Problems Easy for Tree-Decomposable Graphs (Extended Abstract)

    Stefan Arnborg;Jens Lagergren;Detlef Seese

  • The gene evolution model and computing its associated probabilities

    Lars Arvestad;Jens Lagergren;Bengt Sennblad

  • Simultaneous identification of duplications and lateral transfers

    Mike Hallett;Jens Lagergren;Ali Tofigh

  • Fast neighbor joining

    Isaac Elias;Jens Lagergren

  • MSCAN: identification of functional clusters of transcription factor binding sites

    Wynand B.L. Alkema;Öjvind Johansson;Jens Lagergren;Wyeth W. Wasserman

  • Efficient parallel algorithms for tree-decomposition and related problems

    J. Lagergren

  • Finding minimal forbidden minors using a finite congruence

    Jens Lagergren;Stefan Arnborg

  • Problems Easy for Tree-Decomposable Graphs

    Stefan Arnborg;Jens Lagergren;Detlef Seese

Frequent Co-Authors

Alessandro Panconesi
Alessandro Panconesi Sapienza University of Rome
Nuria Lopez-Bigas
Nuria Lopez-Bigas Institució Catalana de Recerca i Estudis Avançats
Benny Chor
Benny Chor Tel Aviv University
Johan Håstad
Johan Håstad Royal Institute of Technology
Sampsa Hautaniemi
Sampsa Hautaniemi University of Helsinki
Abel Gonzalez-Perez
Abel Gonzalez-Perez Pompeu Fabra University
Wyeth W. Wasserman
Wyeth W. Wasserman University of British Columbia
Joakim Lundeberg
Joakim Lundeberg Royal Institute of Technology
Simon Heath
Simon Heath Pompeu Fabra University

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