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Sampsa Hautaniemi

Sampsa Hautaniemi

D-Index & Metrics

Biology and Biochemistry

D-Index
62
Citations
13480
World Ranking
10821
National Ranking
75

Overview

Sampsa Hautaniemi is affiliated with the University of Helsinki in Finland and specializes in research intersecting biochemistry, genetics, molecular biology, and medicine. Their work spans a range of subfields including molecular biology, cancer research, oncology, reproductive medicine, and pulmonary and respiratory medicine.

The scientist's research primarily focuses on several key topics, such as:

  • Cancer Genomics and Diagnostics
  • Ovarian cancer diagnosis and treatment
  • Single-cell and spatial transcriptomics
  • PARP inhibition in cancer therapy
  • Cancer-related molecular mechanisms research
  • Cancer Cells and Metastasis
  • RNA modifications and cancer

Sampsa Hautaniemi has contributed to numerous publications, especially in venues that include:

  • Cancer Research
  • bioRxiv (Cold Spring Harbor Laboratory)
  • Bioinformatics
  • Clinical Cancer Research
  • Nature Communications

Frequent collaborators in their research include Johanna Hynninen, Jaana Oikkonen, Sakari Hietanen, Kaisa Huhtinen, and Anni Virtanen.

Recent papers by Hautaniemi detail advances in ovarian cancer biology and treatment strategies. These include:

  • "Immunogenomic profiling determines responses to combined PARP and PD-1 inhibition in ovarian cancer," 2020, Nature Communications
  • "Longitudinal single-cell RNA-seq analysis reveals stress-promoted chemoresistance in metastatic ovarian cancer," 2022, Science Advances
  • "Co-evolution of matrisome and adaptive adhesion dynamics drives ovarian cancer chemoresistance," 2021, Nature Communications
  • "A platform for efficient establishment and drug-response profiling of high-grade serous ovarian cancer organoids," 2023, Developmental Cell
  • "Evolutionary states and trajectories characterized by distinct pathways stratify patients with ovarian high grade serous carcinoma," 2023, Cancer Cell

Their publication record shows a consistent engagement with topics addressing the molecular underpinnings of ovarian cancer, chemoresistance mechanisms, and the tumor microenvironment.

Best Publications

  • Impact of DNA Amplification on Gene Expression Patterns in Breast Cancer

    Elizabeth Hyman;Päivikki Kauraniemi;Sampsa Hautaniemi;Maija Wolf

  • Multiple reaction monitoring for robust quantitative proteomic analysis of cellular signaling networks

    Alejandro Wolf-Yadlin;Sampsa Hautaniemi;Douglas A. Lauffenburger;Forest M. White

  • Dual role of FoxA1 in androgen receptor binding to chromatin, androgen signalling and prostate cancer

    Biswajyoti Sahu;Marko Laakso;Kristian Ovaska;Tuomas Mirtti;Tuomas Mirtti

  • PINA v2.0: mining interactome modules

    Mark J. Cowley;Mark Pinese;Karin S. Kassahn;Nic Waddell

  • Integrated network analysis platform for protein-protein interactions

    Jianmin Wu;Tea Vallenius;Kristian Ovaska;Jukka Westermarck;Jukka Westermarck

  • Systematic bioinformatic analysis of expression levels of 17,330 human genes across 9,783 samples from 175 types of healthy and pathological tissues.

    Sami Kilpinen;Sami Kilpinen;Reija Autio;Kalle Ojala;Kalle Ojala;Kristiina Iljin

  • Effects of HER2 overexpression on cell signaling networks governing proliferation and migration

    Alejandro Wolf-Yadlin;Neil Kumar;Yi Zhang;Sampsa Hautaniemi

  • Are data from different gene expression microarray platforms comparable

    Anna-Kaarina Järvinen;Sampsa Hautaniemi;Henrik Edgren;Henrik Edgren;Petri Auvinen

  • FoxA1 specifies unique androgen and glucocorticoid receptor binding events in prostate cancer cells.

    Biswajyoti Sahu;Marko Laakso;Päivi Pihlajamaa;Kristian Ovaska

  • Nonsense-mediated decay microarray analysis identifies mutations of EPHB2 in human prostate cancer.

    Pia Huusko;Damaris Ponciano-Jackson;Maija Wolf;Jeff A. Kiefer

  • RNAi microarray analysis in cultured mammalian cells.

    Spyro Mousses;Natasha J. Caplen;Robert Cornelison;Don Weaver

  • Large-scale data integration framework provides a comprehensive view on glioblastoma multiforme

    Kristian Ovaska;Marko Laakso;Saija Haapa-Paananen;Riku Louhimo

  • Immunogenomic profiling determines responses to combined PARP and PD-1 inhibition in ovarian cancer.

    Anniina Färkkilä;Doga C. Gulhan;Julia Casado;Connor A. Jacobson

  • High-resolution analysis of gene copy number alterations in human prostate cancer using CGH on cDNA microarrays: impact of copy number on gene expression.

    Maija Wolf;Spyro Mousses;Sampsa Hautaniemi;Ritva Karhu

  • Early recovery from cow's milk allergy is associated with decreasing IgE and increasing IgG4 binding to cow's milk epitopes

    Emma M. Savilahti;Ville Rantanen;Jing S. Lin;Sirkku Karinen

  • Optimized LOWESS normalization parameter selection for DNA microarray data

    John A Berger;Sampsa Hautaniemi;Anna-Kaarina Järvinen;Henrik Edgren;Henrik Edgren

  • Characterising metabolically healthy obesity in weight-discordant monozygotic twins.

    J. Naukkarinen;S. Heinonen;A. Hakkarainen;J. Lundbom

  • Gene-expression profiling predicts recurrence in Dukes' C colorectal cancer.

    Diego Arango;Paivi Laiho;Antti Kokko;Pia Alhopuro

  • High-resolution genomic and expression profiling reveals 105 putative amplification target genes in pancreatic cancer.

    Eija H. Mahlamaki;Päivikki Kauraniemi;Outi Monni;Maija Wolf

  • Comprehensive evaluation of coding region point mutations in microsatellite‐unstable colorectal cancer

    Johanna Kondelin;Kari Salokas;Lilli Saarinen;Kristian Ovaska

Frequent Co-Authors

Olli Carpén
Olli Carpén University of Helsinki
Outi Monni
Outi Monni University of Helsinki
Olli Kallioniemi
Olli Kallioniemi Karolinska Institute
Lauri A. Aaltonen
Lauri A. Aaltonen University of Helsinki
Jaakko Astola
Jaakko Astola Tampere University
Ari Ristimäki
Ari Ristimäki University of Helsinki
Jan Delabie
Jan Delabie University Health Network
Anne Kallioniemi
Anne Kallioniemi Tampere University
Olli A. Jänne
Olli A. Jänne University of Helsinki
Jussi Taipale
Jussi Taipale University of Cambridge

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