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Medicine

D-Index
104
Citations
42707
World Ranking
7017
National Ranking
77

Overview

Aila Rissanen is affiliated with the University of Helsinki in Finland and has contributed extensively to research in the field of medicine. Their work primarily addresses topics related to adipose tissue, metabolism, obesity, and cardiovascular health, with a focus on investigating biological mechanisms and health outcomes associated with body mass and adiposity.

The main fields of study for Rissanen's research include medicine, with subfields covering epidemiology, physiology, cardiology and cardiovascular medicine, public health, environmental and occupational health, as well as clinical psychology. This interdisciplinary approach reflects the complex nature of the health issues studied.

The key topics of research in Rissanen's publications include:

  • Adipokines, inflammation, and metabolic diseases
  • Adipose tissue and metabolism
  • Cardiovascular disease and adiposity
  • Obesity, physical activity, diet
  • Eating disorders and behaviors
  • Blood properties and coagulation
  • Mesenchymal stem cell research

Rissanen has collaborated with various frequent coauthors who have contributed to the breadth of their scientific output. Notable collaborators include:

  • Jaakko Kaprio (7 joint publications)
  • Kirsi H. Pietiläinen (6 joint publications)
  • Sini Heinonen (4 joint publications)
  • Maheswary Muniandy (2 joint publications)
  • Antti Hakkarainen (2 joint publications)

The research has been published in multiple scientific venues, illustrating the diverse scope of topics and their interdisciplinary nature. Frequent publication venues include:

  • Cell Reports Medicine
  • International Journal of Molecular Sciences
  • Stem Cell Research & Therapy
  • Matrix Biology
  • Sleep Health

Some of the recent papers authored or coauthored by Rissanen are:

  • "Molecular pathways behind acquired obesity: Adipose tissue and skeletal muscle multiomics in monozygotic twin pairs discordant for BMI" (2021), published in Cell Reports Medicine
  • "Transglutaminases and Obesity in Humans: Association of F13A1 to Adipocyte Hypertrophy and Adipose Tissue Immune Response" (2020), published in International Journal of Molecular Sciences
  • "Evaluation of the effect of donor weight on adipose stromal/stem cell characteristics by using weight-discordant monozygotic twin pairs" (2021), published in Stem Cell Research & Therapy
  • "Matrisome alterations in obesity - Adipose tissue transcriptome study on monozygotic weight-discordant twins" (2022), published in Matrix Biology
  • "Sleep and lifestyle in young adult monozygotic twin pairs discordant for body mass index" (2021), published in Sleep Health

This body of work sheds light on mechanisms underpinning obesity and its associated metabolic and cardiovascular disorders, employing approaches that range from molecular biology to epidemiological studies and lifestyle assessments.

Best Publications

  • Hundreds of variants clustered in genomic loci and biological pathways affect human height

    Hana Lango Allen;Karol Estrada;Guillaume Lettre;Sonja I. Berndt

  • Effects of the cannabinoid-1 receptor blocker rimonabant on weight reduction and cardiovascular risk factors in overweight patients: 1-year experience from the RIO-Europe study

    Luc F Van Gaal;Aila M Rissanen;André J Scheen;Olivier Ziegler

  • Randomised placebo-controlled trial of orlistat for weight loss and prevention of weight regain in obese patients

    Lars Sjostrom;Aila Rissanen;Teis Andersen;Mark Boldrin

  • Effects of liraglutide in the treatment of obesity: a randomised, double-blind, placebo-controlled study

    Arne Astrup;Stephan Rössner;Luc Van Gaal;Aila Rissanen

  • How much physical activity is enough to prevent unhealthy weight gain? Outcome of the IASO 1st Stock Conference and consensus statement

    W. H. M. Saris;S. N. Blair;M. A. van Baak;S. B. Eaton

  • Meta-analysis identifies 13 new loci associated with waist-hip ratio and reveals sexual dimorphism in the genetic basis of fat distribution

    Iris M. Heid;Anne U. Jackson;Joshua C. Randall;Tthomas W. Winkler

  • Breakfast skipping and health-compromising behaviors in adolescents and adults.

    Anna Keski-Rahkonen;J. Kaprio;A. Rissanen;M. Virkkunen

  • Safety, tolerability and sustained weight loss over 2 years with the once-daily human GLP-1 analog, liraglutide.

    A Astrup;R Carraro;N Finer;A Harper

  • Prediction of non-alcoholic fatty liver disease and liver fat using metabolic and genetic factors.

    Anna Kotronen;Markku Peltonen;Antti Hakkarainen;Ksenia Sevastianova

  • Epidemiology and Course of Anorexia Nervosa in the Community

    Anna Keski-Rahkonen;Hans W. Hoek;Ezra S. Susser;Milla S. Linna

  • 3 years of liraglutide versus placebo for type 2 diabetes risk reduction and weight management in individuals with prediabetes: a randomised, double-blind trial

    Carel W le Roux;Carel W le Roux;Arne Astrup;Ken Fujioka;Frank Greenway

  • A European Evidence-Based Guideline for the Prevention of Type 2 Diabetes

    B. Paulweber;P. Valensi;J. Lindström;N. M. Lalic

  • Physical inactivity and obesity: a vicious circle

    Kirsi H. Pietiläinen;Jaakko Kaprio;Patrik Borg;Guy Plasqui

  • Dietary fat content modifies liver fat in overweight nondiabetic subjects.

    Jukka Westerbacka;Katriina Lammi;Anna-Maija Häkkinen;Aila Rissanen

  • Effects of weight loss with orlistat on glucose tolerance and progression to type 2 diabetes in obese adults.

    Steven B. Heymsfield;Karen R. Segal;Jonathan Hauptman;Charles P. Lucas

  • Acquired obesity is associated with changes in the serum lipidomic profile independent of genetic effects - A monozygotic twin study

    Kirsi H. Pietiläinen;Kirsi H. Pietiläinen;Marko Sysi-Aho;Aila Rissanen;Tuulikki Seppänen-Laakso

  • FGF-21 as a biomarker for muscle-manifesting mitochondrial respiratory chain deficiencies: a diagnostic study.

    Anu Suomalainen;Anu Suomalainen;Jenni M Elo;Kirsi H Pietiläinen;Anna H Hakonen

  • Bacterial Endotoxin Activity in Human Serum Is Associated With Dyslipidemia, Insulin Resistance, Obesity, and Chronic Inflammation

    Mariann I. Lassenius;Kirsi H. Pietiläinen;Kati Kaartinen;Pirkko J. Pussinen

  • Sex-differences in heritability of BMI: A comparative study of results from Twin Studies in Eight Countries

    Karoline Schousboe;Gonneke Willemsen;Kirsten O. Kyvik;Jakob Mortensen

  • Effects of Identical Weight Loss on Body Composition and Features of Insulin Resistance in Obese Women With High and Low Liver Fat Content

    Mirja Tiikkainen;Robert Bergholm;Satu Vehkavaara;Aila Rissanen

Frequent Co-Authors

Jaakko Kaprio
Jaakko Kaprio University of Helsinki
Kirsi H. Pietiläinen
Kirsi H. Pietiläinen University of Helsinki
Hannele Yki-Järvinen
Hannele Yki-Järvinen University of Helsinki
Richard J. Rose
Richard J. Rose Indiana University
Leo Niskanen
Leo Niskanen University of Helsinki
Jari Tiihonen
Jari Tiihonen Karolinska Institute
Thorkild I. A. Sørensen
Thorkild I. A. Sørensen University of Copenhagen
Leif Groop
Leif Groop Lund University
Nilesh J. Samani
Nilesh J. Samani University of Leicester
Anders Hamsten
Anders Hamsten Karolinska Institute

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