World's Best Scientists 2026 revealed!
Jean-Charles Sanchez

Jean-Charles Sanchez

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Biology and Biochemistry
Switzerland
2023

D-Index & Metrics

Biology and Biochemistry

D-Index
84
Citations
41046
World Ranking
3238
National Ranking
69

Research.com Recognitions

  • 2023 - Research.com Biology and Biochemistry in Switzerland Leader Award

Overview

Jean-Charles Sanchez is a researcher affiliated with the University of Geneva in Switzerland, with a focus on medicine and biochemistry, genetics, and molecular biology. Their body of work spans various subfields including epidemiology, neurology, molecular biology, surgery, and emergency medicine.

The main topics covered in their research involve acute ischemic stroke management, traumatic brain injury and neurovascular disturbances, S100 proteins and annexins, sepsis diagnosis and treatment, pneumonia and respiratory infections, neuroinflammation and neurodegeneration mechanisms, and extracellular vesicles in disease.

Among recent publications by Jean-Charles Sanchez are:

  • "Multilevel omics for the discovery of biomarkers and therapeutic targets for stroke," 2020, Nature Reviews Neurology
  • "Neuroinflammatory Response to TNFα and IL1β Cytokines Is Accompanied by an Increase in Glycolysis in Human Astrocytes In Vitro," 2021, International Journal of Molecular Sciences
  • "Para-infectious brain injury in COVID-19 persists at follow-up despite attenuated cytokine and autoantibody responses," 2023, Nature Communications
  • "Interleukin 10 and Heart Fatty Acid-Binding Protein as Early Outcome Predictors in Patients With Traumatic Brain Injury," 2020, Frontiers in Neurology
  • "SAA (Serum Amyloid A)," 2020, Stroke

Their frequent co-authors include Leire Azurmendi, Joan Montaner, Domitille Schvartz, Tom Solomon, and J. Kenneth Baillie.

Jean-Charles Sanchez publishes regularly in several scientific journals with multiple publications appearing in the International Journal of Molecular Sciences, Nature Communications, Frontiers in Neurology, Molecular Neurobiology, and Nature Reviews Neurology.

Best Publications

  • pROC: an open-source package for R and S+ to analyze and compare ROC curves

    Xavier Arnaud Robin;Natacha Turck;Alexandre Hainard;Natalia Tiberti

  • Progress with Proteome Projects: Why all Proteins Expressed by a Genome Should be Identified and How To Do It

    Marc R. Wilkins;Jean-Charles Sanchez;Andrew A. Gooley;Ron David Appel

  • From Proteins to Proteomes: Large Scale Protein Identification by Two-Dimensional Electrophoresis and Amino Acid Analysis

    Marc R. Wilkins;Christian Pasquali;Ron D. Appel;Keli Ou

  • The focusing positions of polypeptides in immobilized pH gradients can be predicted from their amino acid sequences

    Bengt Bjellqvist;Graham J. Hughes;Christian Pasquali;Nicole Paquet

  • The dynamic range of protein expression: a challenge for proteomic research.

    Garry L. Corthals;Valerie C. Wasinger;Denis F. Hochstrasser;Jean-Charles Sanchez

  • Proteomics: new perspectives, new biomedical opportunities

    Rosamonde E Banks;Michael J Dunn;Denis F Hochstrasser;Jean-Charles Sanchez

  • Extraction of membrane proteins by differential solubilization for separation using two-dimensional gel electrophoresis

    Mark P. Molloy;Ben R. Herbert;Bradley J. Walsh;Margaret I. Tyler

  • Relative Quantification of Proteins in Human Cerebrospinal Fluids by MS/MS Using 6-Plex Isobaric Tags

    Loïc Dayon;Alexandre Hainard;Virginie Licker;Natacha Turck

  • Functional Proteomic Analysis of Human Nucleolus

    Alexander Scherl;Yohann Couté;Catherine Déon;Aleth Callé

  • A panel of cerebrospinal fluid potential biomarkers for the diagnosis of Alzheimer's disease.

    Odile Carrette;Isabelle Demalte;Alexander Scherl;Oezkarn Yalkinoglu

  • Detailed peptide characterization using PEPTIDEMASS : a World-Wide-Web-accessible tool

    Marc R Wilkins;Marc R Wilkins;Ingrid Lindskog;Elisabeth Gasteiger;Amos Marc Bairoch

  • Improved and simplified in‐gel sample application using reswelling of dry immobilized pH gradients

    Jean-Charles Sanchez;Véronique Rouge;Michel Pisteur;Florence Ravier

  • A nonlinear wide-range immobilized pH gradient for two-dimensional electrophoresis and its definition in a relevant pH scale.

    Bengt Bjellqvist;Christian Pasquali;Florence Ravier;Jean‐Charles Sanchez

  • High-throughput mass spectrometric discovery of protein post-translational modifications.

    Marc Wilkins;Marc Wilkins;Marc Wilkins;Elisabeth Gasteiger;Elisabeth Gasteiger;Andrew A Gooley;Ben R Herbert

  • Protein expression profiles in human breast ductal carcinoma and histologically normal tissue.

    Luca Bini;Barbara Magi;Barbara Marzocchi;Felice Arcuri

  • Characterisation and properties of ectosomes released by human polymorphonuclear neutrophils.

    Olivier Gasser;Christoph Hess;Sylvie Miot;Catherine Deon

  • Colloidal carriers for intravenous drug targeting: Plasma protein adsorption patterns on surface‐modified latex particles evaluated by two‐dimensional polyacrylamide gel electrophoresis

    Torsten Blunk;Denis F. Hochstrasser;Jean-Charles Sanchez;Bernd W. Müller

  • A gene encoding a novel RFX-associated transactivator is mutated in the majority of MHC class II deficiency patients

    Krzysztof Masternak;Emmanuèle Barras;Madeleine Zufferey;Bernard Conrad

  • Two-dimensional gel electrophoresis for proteome projects: The effects of protein hydrophobicity and copy number

    Marc Wilkins;Marc Wilkins;Elisabeth Gasteiger;Jean-Charles Sanchez;Amos Marc Bairoch

  • Current challenges and future applications for protein maps and post‐translational vector maps in proteome projects

    Marc R. Wilkins;Jean-Charles Sanchez;Keith L. Williams;Denis F. Hochstrasser

Frequent Co-Authors

Denis F. Hochstrasser
Denis F. Hochstrasser University of Geneva
Ron D. Appel
Ron D. Appel Swiss Institute of Bioinformatics
Marc R. Wilkins
Marc R. Wilkins University of New South Wales
Yohann Couté
Yohann Couté Grenoble Alpes University
Amos Marc Bairoch
Amos Marc Bairoch Swiss Institute of Bioinformatics
Joan Montaner
Joan Montaner Autonomous University of Barcelona
Keith L. Williams
Keith L. Williams Macquarie University
Frédérique Lisacek
Frédérique Lisacek University of Geneva
Andrew A. Gooley
Andrew A. Gooley Trajan Scientific and Medical
Elisabeth Gasteiger
Elisabeth Gasteiger Swiss Institute of Bioinformatics

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