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Janet A. Houghton

Janet A. Houghton

Cleveland Clinic
United States

D-Index & Metrics

Biology and Biochemistry

D-Index
62
Citations
10272
World Ranking
11052
National Ranking
4776

Janet A. Houghton publication distribution in Biology and Biochemistry in 2026

The chart shows the distribution of publications by all Research.com ranked scientists in the field of Biology and Biochemistry in 2026. The highlighted bar marks where Janet A. Houghton sits on this spectrum.

47–56 publications: 8 scientists 57–66 publications: 35 scientists 67–76 publications: 106 scientists 77–86 publications: 231 scientists 87–96 publications: 414 scientists 97–106 publications: 546 scientists 107–116 publications: 704 scientists 117–126 publications: 849 scientists 127–136 publications: 980 scientists 137–146 publications: 942 scientists 147–156 publications: 969 scientists 157–166 publications: 950 scientists 167–176 publications: 951 scientists 177–186 publications: 915 scientists 187–196 publications: 787 scientists 197–206 publications: 841 scientists 207–216 publications: 735 scientists 217–226 publications: 709 scientists 227–236 publications: 651 scientists 237–246 publications: 605 scientists 247–256 publications: 510 scientists 257–266 publications: 524 scientists 267–276 publications: 434 scientists 277–286 publications: 418 scientists 287–296 publications: 350 scientists 297–306 publications: 363 scientists 307–316 publications: 315 scientists 317–326 publications: 296 scientists 327–336 publications: 261 scientists 337–346 publications: 240 scientists 347–356 publications: 219 scientists 357–366 publications: 197 scientists 367–376 publications: 154 scientists 377–386 publications: 161 scientists 387–396 publications: 155 scientists 397–406 publications: 145 scientists 407–416 publications: 124 scientists 417–426 publications: 112 scientists 427–436 publications: 132 scientists 437–446 publications: 116 scientists 447–456 publications: 99 scientists 457–466 publications: 81 scientists 467–476 publications: 91 scientists 477–486 publications: 80 scientists 487–496 publications: 80 scientists 497–506 publications: 60 scientists 507–516 publications: 36 scientists 517–526 publications: 46 scientists 527–536 publications: 54 scientists 537–546 publications: 44 scientists 547–556 publications: 43 scientists 557–566 publications: 43 scientists 567–576 publications: 42 scientists 577–586 publications: 25 scientists 587–596 publications: 34 scientists 597–606 publications: 23 scientists 607–616 publications: 33 scientists 617–626 publications: 31 scientists 627–636 publications: 27 scientists 637–646 publications: 25 scientists 647–656 publications: 28 scientists 657–666 publications: 34 scientists 667–676 publications: 18 scientists 677–686 publications: 16 scientists 687–696 publications: 10 scientists 697–706 publications: 12 scientists 707–716 publications: 21 scientists 717–726 publications: 12 scientists 727–736 publications: 12 scientists 737–746 publications: 10 scientists 747–756 publications: 7 scientists 757–766 publications: 13 scientists 767–776 publications: 15 scientists 777–786 publications: 13 scientists 787–796 publications: 9 scientists 797–806 publications: 9 scientists 807–816 publications: 7 scientists 817–826 publications: 4 scientists 827–836 publications: 9 scientists 837–846 publications: 7 scientists 847–856 publications: 3 scientists 857–866 publications: 5 scientists 867–876 publications: 5 scientists 877–886 publications: 11 scientists 887–896 publications: 3 scientists 897–906 publications: 4 scientists 907–916 publications: 7 scientists 917–926 publications: 5 scientists 927–936 publications: 6 scientists 937–946 publications: 6 scientists 947–956 publications: 3 scientists 957–966 publications: 7 scientists 967–976 publications: 2 scientists 977–986 publications: 2 scientists 987–996 publications: 1 scientists 997–1,006 publications: 5 scientists 1,007–1,016 publications: 2 scientists 1,017–1,026 publications: 2 scientists 1,027 publications: 1 scientists 1,028+ publications: 100 scientists
47 publications 1,028+

This scientist: 188 publications — 45th percentile

45% of scientists in this discipline score the same or lower.

The last bar groups every scientist with 1,028 publications or more.

Janet A. Houghton D-index placement in Biology and Biochemistry in 2026

The chart shows the D-index (discipline H-index) distribution of Biology and Biochemistry scientists ranked by Research.com in 2026. The highlighted bar marks where Janet A. Houghton sits on this spectrum.

40–41 D-Index: 80 scientists 42–43 D-Index: 183 scientists 44–45 D-Index: 317 scientists 46–47 D-Index: 504 scientists 48–49 D-Index: 718 scientists 50–51 D-Index: 900 scientists 52–53 D-Index: 1,026 scientists 54–55 D-Index: 1,150 scientists 56–57 D-Index: 1,236 scientists 58–59 D-Index: 1,253 scientists 60–61 D-Index: 1,163 scientists 62–63 D-Index: 1,131 scientists 64–65 D-Index: 1,032 scientists 66–67 D-Index: 897 scientists 68–69 D-Index: 814 scientists 70–71 D-Index: 715 scientists 72–73 D-Index: 709 scientists 74–75 D-Index: 596 scientists 76–77 D-Index: 512 scientists 78–79 D-Index: 473 scientists 80–81 D-Index: 412 scientists 82–83 D-Index: 373 scientists 84–85 D-Index: 358 scientists 86–87 D-Index: 285 scientists 88–89 D-Index: 273 scientists 90–91 D-Index: 227 scientists 92–93 D-Index: 208 scientists 94–95 D-Index: 193 scientists 96–97 D-Index: 153 scientists 98–99 D-Index: 157 scientists 100–101 D-Index: 148 scientists 102–103 D-Index: 120 scientists 104–105 D-Index: 113 scientists 106–107 D-Index: 100 scientists 108–109 D-Index: 86 scientists 110–111 D-Index: 67 scientists 112–113 D-Index: 72 scientists 114–115 D-Index: 73 scientists 116–117 D-Index: 64 scientists 118–119 D-Index: 53 scientists 120–121 D-Index: 60 scientists 122–123 D-Index: 54 scientists 124–125 D-Index: 43 scientists 126–127 D-Index: 38 scientists 128–129 D-Index: 49 scientists 130–131 D-Index: 26 scientists 132–133 D-Index: 18 scientists 134–135 D-Index: 23 scientists 136–137 D-Index: 32 scientists 138–139 D-Index: 32 scientists 140–141 D-Index: 27 scientists 142–143 D-Index: 19 scientists 144–145 D-Index: 22 scientists 146–147 D-Index: 12 scientists 148–149 D-Index: 16 scientists 150–151 D-Index: 14 scientists 152–153 D-Index: 10 scientists 154–155 D-Index: 13 scientists 156–157 D-Index: 10 scientists 158–159 D-Index: 7 scientists 160–161 D-Index: 9 scientists 162–163 D-Index: 13 scientists 164–165 D-Index: 4 scientists 166 D-Index: 4 scientists 167+ D-Index: 98 scientists
40 D-Index 167+

This scientist: 62 D-Index — 46th percentile

46% of scientists in this discipline score the same or lower.

The last bar groups every scientist with 167 D-Index or more.

Overview

Janet A. Houghton was affiliated with the Cleveland Clinic in the United States during their career. Their work concentrated within the domain of medical research, although specific subfields and main topics of study have not been documented in the available data.

Details regarding recent papers, frequent co-authors, or publication venues linked to Janet A. Houghton are not listed, and no record of published books is available. Likewise, there is no information concerning awards or recognitions received throughout their career.

The absence of detailed records on research output, collaborations, and sub-specializations limits a deeper insight into the precise nature and impact of their scientific contributions. Nonetheless, their association with a major clinical institution such as the Cleveland Clinic suggests involvement in clinical or biomedical research contexts.

Janet A. Houghton has been confirmed deceased, and all references to their work are made in past tense to reflect this status.

Best Publications

  • Targeting autophagy augments the anticancer activity of the histone deacetylase inhibitor SAHA to overcome Bcr-Abl-mediated drug resistance

    Jennifer S. Carew;Steffan T. Nawrocki;Charissa N. Kahue;Hui Zhang

  • Efficacy of topoisomerase I inhibitors, topotecan and irinotecan, administered at low dose levels in protracted schedules to mice bearing xenografts of human tumors

    Peter J. Houghton;Pamela J. Cheshire;James D. Hallman;Lois Lutz

  • Evaluation of 9-dimethylaminomethyl-10-hydroxycamptothecin against xenografts derived from adult and childhood solid tumors.

    Peter J. Houghton;Pamela J. Cheshire;Leann Myers;Clinton F. Stewart

  • Biochemical determinants of responsiveness to 5-fluorouracil and its derivatives in xenografts of human colorectal adenocarcinomas in mice.

    Janet A. Houghton;Stephen J. Maroda;John O. Phillips;Peter J. Houghton

  • Therapeutic Efficacy of the Topoisomerase I Inhibitor 7-Ethyl-10-(4-[1-piperidino]-1-piperidino)-carbonyloxy-camptothecin against Human Tumor Xenografts: Lack of Cross-Resistance in Vivo in Tumors with Acquired Resistance to the Topoisomerase I Inhibitor 9-Dimethylaminomethyl-10-hydroxycamptothecin

    Peter J. Houghton;Pamela J. Cheshire;James C. Hallman;Marie C. Bissery

  • Thymineless death in colon carcinoma cells is mediated via Fas signaling

    Janet A. Houghton;Franklin G. Harwood;David M. Tillman

  • Hedgehog signaling drives cellular survival in human colon carcinoma cells.

    Tapati Mazumdar;Jennifer DeVecchio;Ting Shi;Janay Jones

  • Biology of childhood osteogenic sarcoma and potential targets for therapeutic development : Meeting summary

    Richard Gorlick;Peter Anderson;Irene Andrulis;Carola Arndt

  • Shared pathways: death receptors and cytotoxic drugs in cancer therapy.

    Istvan Petak;Janet A. Houghton

  • Mechanism of induction of gastrointestinal toxicity in the mouse by 5-fluorouracil, 5-fluorouridine, and 5-fluoro-2'-deoxyuridine.

    Janet A. Houghton;Peter J. Houghton;Robert S. Wooten

  • Relationship between topotecan systemic exposure and tumor response in human neuroblastoma xenografts.

    William C. Zamboni;Clinton F. Stewart;Joyce Thompson;Victor M. Santana

  • O6-Alkylguanine-DNA alkyltransferase activity correlates with the therapeutic response of human rhabdomyosarcoma xenografts to 1-(2-chloroethyl)-3-(trans-4-methylcyclohexyl)-1-nitrosourea

    T P Brent;P J Houghton;J A Houghton

  • Efficacy of systemic administration of irinotecan against neuroblastoma xenografts.

    Joyce Thompson;William C. Zamboni;Pamela J. Cheshire;Lois Lutz

  • Blocking Hedgehog Survival Signaling at the Level of the GLI Genes Induces DNA Damage and Extensive Cell Death in Human Colon Carcinoma Cells

    Tapati Mazumdar;Jennifer DeVecchio;Akwasi Agyeman;Ting Shi

  • Apoptosis and drug response

    Janet A. Houghton

  • Myc regulates aggresome formation, the induction of Noxa, and apoptosis in response to the combination of bortezomib and SAHA.

    Steffan T. Nawrocki;Steffan T. Nawrocki;Jennifer S. Carew;Kirsteen H. Maclean;James F. Courage

  • Therapeutic efficacy of the topoisomerase I inhibitor 7-ethyl-10-(4-[1-piperidino]-1-piperidino)-carbonyloxy-camptothecin against pediatric and adult central nervous system tumor xenografts.

    C. Bradley Hare;Gertrude B. Elion;Peter J. Houghton;Janet A. Houghton

  • p53 dependence of Fas induction and acute apoptosis in response to 5-fluorouracil-leucovorin in human colon carcinoma cell lines.

    Istvan Petak;David M. Tillman;Janet A. Houghton

  • Rottlerin sensitizes colon carcinoma cells to tumor necrosis factor-related apoptosis-inducing ligand-induced apoptosis via uncoupling of the mitochondria independent of protein kinase C.

    David M Tillman;Kamel Izeradjene;Kinga Szekely Szucs;Leslie Douglas

  • Phase II testing of melphalan in children with newly diagnosed rhabdomyosarcoma: a model for anticancer drug development.

    M. E. Horowitz;E. Etcubanas;M. L. Christensen;Janet A Houghton

Frequent Co-Authors

Peter J. Houghton
Peter J. Houghton The University of Texas Health Science Center at San Antonio
Clinton F. Stewart
Clinton F. Stewart St. Jude Children's Research Hospital
John L. Cleveland
John L. Cleveland Moffitt Cancer Center
Henry S. Friedman
Henry S. Friedman Duke University
Peng Huang
Peng Huang Sun Yat-sen University
Mary K. Danks
Mary K. Danks St. Jude Children's Research Hospital
William T. Beck
William T. Beck University of Illinois at Chicago
Robert A. Casero
Robert A. Casero Johns Hopkins University School of Medicine
Douglas R. Green
Douglas R. Green St. Jude Children's Research Hospital
Irene L. Andrulis
Irene L. Andrulis University of Toronto

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Best Scientists Citing Janet A. Houghton

Peter J. Houghton

Peter J. Houghton

The University of Texas Health Science Center at San Antonio

Publications: 94

Clinton F. Stewart

Clinton F. Stewart

St. Jude Children's Research Hospital

Publications: 82

Henry S. Friedman

Henry S. Friedman

Duke University

Publications: 34

Godefridus J. Peters

Godefridus J. Peters

Gdańsk Medical University

Publications: 30

Philip M. Potter

Philip M. Potter

St. Jude Children's Research Hospital

Publications: 27

Mary K. Danks

Mary K. Danks

St. Jude Children's Research Hospital

Publications: 26

Simone Fulda

Simone Fulda

Goethe University Frankfurt

Publications: 25

Jos H. Beijnen

Jos H. Beijnen

Utrecht University

Publications: 24

Charles B. Pratt

Charles B. Pratt

St. Jude Children's Research Hospital

Publications: 24

Patrick G. Johnston

Patrick G. Johnston

Queen's University Belfast

Publications: 24

Jaap Verweij

Jaap Verweij

Erasmus University Rotterdam

Publications: 24

Alberto S. Pappo

Alberto S. Pappo

St. Jude Children's Research Hospital

Publications: 22

Gérard Milano

Gérard Milano

Université Côte d'Azur

Publications: 21

Richard Gorlick

Richard Gorlick

The University of Texas MD Anderson Cancer Center

Publications: 21

H.M. Pinedo

H.M. Pinedo

Vrije Universiteit Amsterdam

Publications: 21

Tong-Chuan He

Tong-Chuan He

University of Chicago

Publications: 21

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