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Biology and Biochemistry

D-Index
91
Citations
41155
World Ranking
2280
National Ranking
153

Research.com Recognitions

  • 1991 - Member of Academia Europaea
  • 1988 - Fellow of the Royal Society, United Kingdom
  • Fellow of The Academy of Medical Sciences, United Kingdom
  • Member of the European Molecular Biology Organization (EMBO)
  • Fellow of The Academy of Medical Sciences, United Kingdom
  • Member of the European Molecular Biology Organization (EMBO)
  • Fellow of The Academy of Medical Sciences, United Kingdom
  • Member of the European Molecular Biology Organization (EMBO)

Overview

Hugh R.B. Pelham is affiliated with the MRC Laboratory of Molecular Biology in the United Kingdom. Their research spans several fields, notably Medicine, Biochemistry, Genetics and Molecular Biology, and Immunology and Microbiology. The scientist's work covers multiple subfields including Public Health, Environmental and Occupational Health, Molecular Biology, and Microbiology.

The main topics addressed in their research include Neonatal and Maternal Infections, Bacterial Infections and Vaccines, Streptococcal Infections and Treatments, Wnt/β-catenin signaling in development and cancer, Cancer-related gene regulation, and RNA Research and Splicing.

Notable papers authored or co-authored by Hugh R.B. Pelham include:

  • Regulation of Dishevelled DEP domain swapping by conserved phosphorylation sites, 2021, Proceedings of the National Academy of Sciences
  • Towards accurate exclusion of neonatal bacterial meningitis: a feasibility study of a novel 16S rDNA PCR assay, 2020, BMC Infectious Diseases
  • Towards accurate exclusion of neonatal bacterial meningitis: a feasibility study of a novel 16S rDNA PCR assay., 2020, Research Square (Research Square)

Frequent collaborators in their research include:

  • Arthur Abelian
  • Thomas Mund
  • Martin D. Curran
  • Stuart Savill
  • Nipa Mitra

The venues where Hugh R.B. Pelham regularly publishes include Proceedings of the National Academy of Sciences, BMC Infectious Diseases, and Research Square (Research Square).

Throughout their career, this scientist has been recognized with several honors. They have been named a Member of Academia Europaea in 1991. They are a Fellow of the Royal Society, United Kingdom since 1988, and they hold fellowships with The Academy of Medical Sciences, United Kingdom. Additionally, they are a Member of the European Molecular Biology Organization (EMBO).

Best Publications

  • An efficient mRNA-dependent translation system from reticulocyte lysates.

    Hugh R. B. Pelham;Richard J. Jackson

  • A C-terminal signal prevents secretion of luminal ER proteins

    Sean Munro;Hugh R.B. Pelham

  • Speculations on the functions of the major heat shock and glucose-regulated proteins.

    Hugh R.B. Pelham

  • An Hsp70-like protein in the ER: identity with the 78 kd glucose-regulated protein and immunoglobulin heavy chain binding protein.

    Sean Munro;Hugh R.B. Pelham

  • A regulatory upstream promoter element in the Drosophila Hsp 70 heat-shock gene

    Hugh R.B. Pelham

  • Control of Protein Exit from the Endoplasmic Reticulum

    Hugh R. B. Pelham

  • Yeast heat shock factor is an essential DNA-binding protein that exhibits temperature-dependent phosphorylation

    Peter K. Sorger;Hugh R.B. Pelham

  • The retention signal for soluble proteins of the endoplasmic reticulum

    Hugh R.B. Pelham

  • ERD2, a yeast gene required for the receptor-mediated retrieval of luminal ER proteins from the secretory pathway

    Jan C. Semenza;Kevin G. Hardwick;Neta Dean;Hugh R.B. Pelham

  • Hsp70 accelerates the recovery of nucleolar morphology after heat shock.

    H. R. B. Pelham

  • A specific transcription factor that can bind either the 5S RNA gene or 5S RNA.

    Hugh R. B. Pelham;Donald D. Brown

  • Evidence that luminal ER proteins are sorted from secreted proteins in a post-ER compartment.

    H. R. B. Pelham

  • Heat shock factor is regulated differently in yeast and HeLa cells

    Peter K. Sorger;Michael J. Lewis;Hugh R. B. Pelham

  • Homotypic vacuolar fusion mediated by t- and v-SNAREs

    Benjamin J. Nichols;Christian Ungermann;Hugh R. B. Pelham;William T. Wickner

  • Ligand-induced redistribution of a human KDEL receptor from the Golgi complex to the endoplasmic reticulum.

    Michael J. Lewis;Hugh R.B. Pelham

  • Multiple targets for brefeldin A

    Hugh R.B. Pelham

  • A human homologue of the yeast HDEL receptor.

    Michael J. Lewis;Hugh R. B. Pelham

  • Purification and characterization of a heat-shock element binding protein from yeast.

    P. K. Sorger;H. R. B. Pelham

  • Specific Retrieval of the Exocytic SNARE Snc1p from Early Yeast Endosomes

    Michael J. Lewis;Benjamin J. Nichols;Cristina Prescianotto-Baschong;Howard Riezman

  • Leaky UAG termination codon in tobacco mosaic virus RNA.

    Hugh R. B. Pelham

Frequent Co-Authors

Peter K. Sorger
Peter K. Sorger Harvard University
Sean Munro
Sean Munro MRC Laboratory of Molecular Biology
Julian C. Rayner
Julian C. Rayner University of Cambridge
Joost C. M. Holthuis
Joost C. M. Holthuis Osnabrück University
Fulvio Reggiori
Fulvio Reggiori University of Groningen
Christian Ungermann
Christian Ungermann Osnabrück University
William Wickner
William Wickner Dartmouth College
Mariann Bienz
Mariann Bienz MRC Laboratory of Molecular Biology
Michel Goedert
Michel Goedert MRC Laboratory of Molecular Biology
Andrew Travers
Andrew Travers MRC Laboratory of Molecular Biology

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