H M Korchak

Overview

Best Publications

• Release of inflammatory mediators from stimulated neutrophils.

  Gerald Weissmann;James E. Smolen;Helen M. Korchak

  832
  Citations

• Formation of leukotrienes and other hydroxy acids during platelet-neutrophil interactions in vitro

  Aaron J. Marcus;Aaron J. Marcus;M.Johan Broekman;M.Johan Broekman;Lenore B. Safier;Lenore B. Safier;Harris L. Ullman;Harris L. Ullman

  409
  Citations

• Stimulus response coupling in the human neutrophil. II. Temporal analysis of changes in cytosolic calcium and calcium efflux.

  H M Korchak;K Vienne;L E Rutherford;C Wilkenfeld

  370
  Citations

• Leukotriene B4 is a complete secretagogue in human neutrophils: A kinetic analysis

  Charles N. Serhan;Allen Radin;James E. Smolen;Helen Korchak

  307
  Citations

• Changes in membrane potential of human granulocytes antecede the metabolic responses to surface stimulation.

  H. M. Korchak;Gerald Weissmann

  286
  Citations

• Modes of action of aspirin-like drugs

  Steven Abramson;Helen Korchak;Rocio Ludewig;Henry Edelson

  274
  Citations

• The roles of extracellular and intracellular calcium in lysosomal enzyme release and superoxide anion generation by human neutrophils.

  James E. Smolen;Helen M. Korchak;Gerald Weissmann

  271
  Citations

• Increased levels of cyclic adenosine-3',5'-monophosphate in human polymorphonuclear leukocytes after surface stimulation.

  J E Smolen;H M Korchak;G Weissmann

  263
  Citations

• Effects of non-steroidal anti-inflammatory agents on human neutrophil functions in vitro and in vivo.

  Howard B. Kaplan;Henry S. Edelson;Helen M. Korchak;William P. Given

  251
  Citations

• Protein kinase C isotypes and signaling in neutrophils. Differential substrate specificities of a translocatable calcium- and phospholipid-dependent beta-protein kinase C and a phospholipid-dependent protein kinase which is inhibited by long chain fatty acyl coenzyme A.

  S Majumdar;M W Rossi;T Fujiki;W A Phillips

  222
  Citations

• Stimulus response coupling in the human neutrophil. I. Kinetic analysis of changes in calcium permeability.

  H M Korchak;L E Rutherford;G Weissmann

  220
  Citations

• Activation of the human neutrophil by calcium-mobilizing ligands. II. Correlation of calcium, diacyl glycerol, and phosphatidic acid generation with superoxide anion generation.

  H M Korchak;L B Vosshall;K A Haines;C Wilkenfeld

  181
  Citations

• Long-Chain Acyl CoA Regulation of Protein Kinase C and Fatty Acid Potentiation of Glucose-Stimulated Insulin Secretion in Clonalβ -Cells1

  Gordon C. Yaney;Helen M. Korchak;Barbara E. Corkey

  167
  Citations

• Female hormones reduce neutrophil responsiveness in vitro.

  Jill P. Buyon;Helen M. Korchak;Lorene E. Rutherford;M. Ganguly

  149
  Citations

• Protein kinase C isotypes and signal-transduction in human neutrophils: Selective substrate specificity of calcium-dependent β-PKC and novel calcium-independent nPKC

  Subrata Majumdar;Lauren H. Kane;Michael W. Rossi;Bryan D. Volpp

  148
  Citations

• Changes in phosphatidylinositol and phosphatidic acid in stimulated human neutrophils: Relationship to calcium mobilization, aggregation and superoxide radical generation

  C N Serhan;M J Broekman;H M Korchak;J E Smolen

  143
  Citations

• Occupancy of adenosine receptors raises cyclic AMP alone and in synergy with occupancy of chemoattractant receptors and inhibits membrane depolarization.

  B. N. Cronstein;S. B. Kramer;Elliot Rosenstein;H. M. Korchak

  140
  Citations

• Selective Role for β-Protein Kinase C in Signaling for O⨪2 Generation but Not Degranulation or Adherence in Differentiated HL60 Cells

  Helen M. Korchak;Michael W. Rossi;Laurie E. Kilpatrick

  124
  Citations

• Activation of the neutrophil by calcium-mobilizing ligands. I. A chemotactic peptide and the lectin concanavalin A stimulate superoxide anion generation but elicit different calcium movements and phosphoinositide remodeling.

  H M Korchak;L B Vosshall;G Zagon;P Ljubich

  123
  Citations

• Prostaglandins and inflammation: receptor/cyclase coupling as an explanation of why PGEs and PGI2 inhibit functions of inflammatory cells.

  G Weissmann;J E Smolen;H Korchak

  123
  Citations