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Biology and Biochemistry

D-Index
60
Citations
13272
World Ranking
11928
National Ranking
919

Overview

Gunter G.C. Kuhnle is affiliated with the University of Reading in the United Kingdom. Their research primarily spans the field of Medicine with a focus on Public Health, Environmental and Occupational Health, Molecular Biology, Physiology, Biochemistry, and Genetics as subfields of study. This multidisciplinary approach intersects with multiple main topics related to Nutritional Studies and Diet, Diet and Metabolism Studies, Metabolomics and Mass Spectrometry Studies, Diet, Metabolism, and Disease, Phytochemicals and Antioxidant Activities, Nutrition, Genetics, and Disease, as well as Biochemical Analysis and Sensing Techniques.

Their recent scholarly output includes several papers published in peer-reviewed journals, covering diverse aspects of nutrition and health. Notable works include:

  • "Flavan-3-ols and Cardiometabolic Health: First Ever Dietary Bioactive Guideline" (2022, Advances in Nutrition)
  • "The ultra-processed foods hypothesis: a product processed well beyond the basic ingredients in the package" (2022, Nutrition Research Reviews)
  • "Gut microbiota composition in relation to intake of added sugar, sugar-sweetened beverages and artificially sweetened beverages in the Malmö Offspring Study" (2020, European Journal of Nutrition)
  • "Assays for the identification and quantification of sialic acids: Challenges, opportunities and future perspectives" (2020, Bioorganic & Medicinal Chemistry)
  • "Dietary flavanols restore hippocampal-dependent memory in older adults with lower diet quality and lower habitual flavanol consumption" (2023, Proceedings of the National Academy of Sciences)

Frequent co-authors contributing to collaborative research efforts with Kuhnle include Javier I. Ottaviani, Hagen Schroeter, Charlotte Mills, Nicola Gray, and Jack Cheeseman.

Their publications often appear in journals specializing in nutrition and food science, indicated by repeated contributions to:

  • Journal of Nutrition
  • European Journal of Nutrition
  • Food & Function
  • bioRxiv (Cold Spring Harbor Laboratory)
  • Molecular Nutrition & Food Research

The scope of Kuhnle's research addresses significant questions related to diet, metabolism, and the biochemical underpinnings of nutritional compounds and their effects on human health. Their work encompasses experimental and analytical methodologies to examine diet-related health outcomes, with emphasis on flavanols, ultra-processed foods, and gut microbiota interactions.

Best Publications

  • Interaction between flavonoids and the blood-brain barrier: in vitro studies.

    Kuresh A. Youdim;Michael S. Dobbie;Gunter Kuhnle;Anna R. Proteggente

  • Colonic metabolism of dietary polyphenols: influence of structure on microbial fermentation products.

    Andreas R Rechner;Martin A Smith;Gunter Kuhnle;Glenn R Gibson

  • The metabolic fate of dietary polyphenols in humans.

    Andreas R Rechner;Gunter Kuhnle;Paul Bremner;Gary P Hubbard

  • Flavanol monomer-induced changes to the human faecal microflora.

    Xenofon Tzounis;Jelena Vulevic;Gunter G. C. Kuhnle;Trevor George

  • The diet-body offset in human nitrogen isotopic values: A controlled dietary study

    T.C. O'Connell;C.J. Kneale;N. Tasevska;G.G.C. Kuhnle;G.G.C. Kuhnle

  • Uptake and metabolism of epicatechin and its access to the brain after oral ingestion.

    Manal M Abd El Mohsen;Gunter Kuhnle;Andreas R Rechner;Hagen Schroeter

  • The Reactive Species Interactome: Evolutionary Emergence, Biological Significance, and Opportunities for Redox Metabolomics and Personalized Medicine.

    Miriam Margherita Cortese-Krott;Anne Koning;Gunter Georg Kuhnle;Peter Nagy

  • Intracellular metabolism and bioactivity of quercetin and its in vivo metabolites.

    Jeremy P E Spencer;Gunter G C Kuhnle;Robert J Williams;Catherine Rice-Evans

  • Resveratrol is absorbed in the small intestine as resveratrol glucuronide.

    G. Kuhnle;J. P. E. Spencer;G. Chowrimootoo;H. Schroeter

  • Novel biomarkers of the metabolism of caffeic acid derivatives in vivo.

    Andreas R Rechner;Jeremy P.E Spencer;Gunter Kuhnle;Ulrich Hahn

  • Key bioactive reaction products of the NO/H2S interaction are S/N-hybrid species, polysulfides, and nitroxyl

    Miriam M. Cortese-Krott;Gunter G. C. Kuhnle;Alex Dyson;Bernadette O. Fernandez

  • Epicatechin and catechin are O-methylated and glucuronidated in the small intestine.

    G Kuhnle;J P E Spencer;H Schroeter;B Shenoy

  • Dietary nitrate improves vascular function in patients with hypercholesterolemia: a randomized, double-blind, placebo-controlled study

    Shanti Velmurugan;Jasmine Ming Gan;Krishnaraj S. Rathod;Rayomand S. Khambata

  • A central role for heme iron in colon carcinogenesis associated with red meat intake

    Nadia M. Bastide;Nadia M. Bastide;Fatima Chenni;Fatima Chenni;Marc Audebert;Raphaelle L. Santarelli

  • Epicatechin and its in vivo metabolite, 3'-O-methyl epicatechin, protect human fibroblasts from oxidative-stress-induced cell death involving caspase-3 activation.

    J P E Spencer;H Schroeter;G Kuhnle;S K S Srai

  • Absorption, tissue distribution and excretion of pelargonidin and its metabolites following oral administration to rats.

    Manal Abd El Mohsen;Joanne Marks;Gunter Kuhnle;Kevin Moore

  • Contrasting influences of glucuronidation and O-methylation of epicatechin on hydrogen peroxide-induced cell death in neurons and fibroblasts.

    Jeremy P.E Spencer;Hagen Schroeter;Andrew J Crossthwaithe;Gunter Kuhnle

  • Human red blood cells at work: identification and visualization of erythrocytic eNOS activity in health and disease

    Miriam M. Cortese-Krott;Ana Rodriguez-Mateos;Roberto Sansone;Gunter G C Kuhnle

  • Re-evaluation of stannous chloride (E 512) as food additive.

    Maged Younes;Peter Aggett

  • Original Contribution COLONIC METABOLISM OF DIETARY POLYPHENOLS: INFLUENCE OF STRUCTURE ON MICROBIAL FERMENTATION PRODUCTS

    Andreas R. Rechner;Martin A. Smith;Gunter Kuhnle;Glenn R. Gibson

Frequent Co-Authors

Catherine Rice-Evans
Catherine Rice-Evans King's College London
Jeremy P. E. Spencer
Jeremy P. E. Spencer University of Reading
Kay-Tee Khaw
Kay-Tee Khaw University of Cambridge
Robert Luben
Robert Luben University College London
Sheila Bingham
Sheila Bingham University of Cambridge
Malte Kelm
Malte Kelm Heinrich Heine University Düsseldorf
Nita G. Forouhi
Nita G. Forouhi University of Cambridge
Martin Feelisch
Martin Feelisch University of Southampton
Glenn R. Gibson
Glenn R. Gibson University of Reading
Tamsin C. O'Connell
Tamsin C. O'Connell University of Cambridge

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