World's Best Scientists 2026 revealed!

D-Index & Metrics

Microbiology

D-Index
89
Citations
29325
World Ranking
718
National Ranking
335

Research.com Recognitions

  • 2012 - Maxwell Finland Award for Scientific Achievement, National Foundation for Infectious Diseases

Overview

George L. Drusano is affiliated with the University of Florida in the United States and has contributed extensively to research in medicine and biochemistry, genetics, and molecular biology. Their work spans multiple subfields, including pharmacology, infectious diseases, epidemiology, molecular medicine, and microbiology.

The scientist's research topics focus primarily on antibiotics pharmacokinetics and efficacy, antibiotic resistance in bacteria, tuberculosis research and epidemiology, reproductive tract infections, Mycobacterium research and diagnosis, pneumonia and respiratory infections, and Pneumocystis jirovecii pneumonia detection and treatment.

Frequent co-authors in their collaborative work include Arnold Louie, Robert A. Bonomo, Sarah Kim, David Brown, and Magnus Unemo.

George L. Drusano's recent publications demonstrate a focus on antimicrobial agents, drug resistance, and clinical infectious diseases. Selected papers include:

  • Rational design of a new antibiotic class for drug-resistant infections, 2021, Nature
  • Optimizing the Use of Beta-Lactam Antibiotics in Clinical Practice: A Test of Time, 2023, Open Forum Infectious Diseases
  • 2-Mercaptomethyl-thiazolidines use conserved aromatic-S interactions to achieve broad-range inhibition of metallo-β-lactamases, 2021, Chemical Science
  • Vancomycin Area Under the Curve-Guided Dosing and Monitoring for Adult and Pediatric Patients With Suspected or Documented Serious Methicillin-Resistant Staphylococcus aureus Infections: Putting the Safety of Our Patients First, 2020, Clinical Infectious Diseases
  • Pharmacodynamic Evaluation of Dosing, Bacterial Kill, and Resistance Suppression for Zoliflodacin Against Neisseria gonorrhoeae in a Dynamic Hollow Fiber Infection Model, 2021, Frontiers in Pharmacology

The scientist publishes frequently in several key venues related to infectious diseases and pharmacology. These include:

  • Antimicrobial Agents and Chemotherapy
  • Frontiers in Pharmacology
  • Clinical Infectious Diseases
  • Open Forum Infectious Diseases
  • Journal of Antimicrobial Chemotherapy

George L. Drusano received the Maxwell Finland Award for Scientific Achievement from the National Foundation for Infectious Diseases in 2012.

Best Publications

  • Antimicrobial pharmacodynamics: critical interactions of 'bug and drug'

    Unknown

  • Individualised antibiotic dosing for patients who are critically ill: challenges and potential solutions

    Jason A Roberts;Jason A Roberts;Mohd H Abdul-Aziz;Jeffrey Lipman;Jeffrey Lipman;Johan W Mouton

  • Pharmacokinetics-Pharmacodynamics of Antimicrobial Therapy: It's Not Just for Mice Anymore

    Paul G. Ambrose;Sujata M. Bhavnani;Christopher M. Rubino;Arnold Louie

  • Larger Vancomycin Doses (at Least Four Grams per Day) Are Associated with an Increased Incidence of Nephrotoxicity

    Thomas P. Lodise;Ben Lomaestro;Jeffrey Graves;G. L. Drusano

  • Relationship between initial vancomycin concentration-time profile and nephrotoxicity among hospitalized patients.

    Thomas P. Lodise;Nimish Patel;Ben M. Lomaestro;Keith A. Rodvold

  • Piperacillin-Tazobactam for Pseudomonas aeruginosa Infection : Clinical Implications of an Extended-Infusion Dosing Strategy

    Thomas P. Lodise;Ben Lomaestro;George L. Drusano

  • Standardization of pharmacokinetic/pharmacodynamic (PK/PD) terminology for anti-infective drugs: an update

    Johan W. Mouton;Michael N. Dudley;Otto Cars;Hartmut Derendorf

  • Prospective Evaluation of the Effect of an Aminoglycoside Dosing Regimen on Rates of Observed Nephrotoxicity and Ototoxicity

    Michael J. Rybak;Michael J. Rybak;Betty J. Abate;S. Lena Kang;Michael J. Ruffing

  • Optimizing Aminoglycoside Therapy for Nosocomial Pneumonia Caused by Gram-Negative Bacteria

    Angela D. M. Kashuba;Anne N. Nafziger;George L. Drusano;Joseph S. Bertino

  • A controlled trial of early versus late treatment with zidovudine in symptomatic human immunodeficiency virus infection. Results of the Veterans Affairs Cooperative Study.

    Hamilton Jd;Hartigan Pm;Simberkoff Ms;Day Pl

  • Are Vancomycin Trough Concentrations Adequate for Optimal Dosing

    Michael N. Neely;Gilmer Youn;Brenda Jones;Roger W. Jelliffe;Roger W. Jelliffe

  • Selection of a Moxifloxacin Dose That Suppresses Drug Resistance in Mycobacterium tuberculosis, by Use of an In Vitro Pharmacodynamic Infection Model and Mathematical Modeling

    Tawanda Gumbo;Arnold Louie;Mark R. Deziel;Linda M. Parsons

  • Pharmacodynamics of a fluoroquinolone antimicrobial agent in a neutropenic rat model of Pseudomonas sepsis

    Unknown

  • Concentration-Dependent Mycobacterium tuberculosis Killing and Prevention of Resistance by Rifampin

    Tawanda Gumbo;Arnold Louie;Mark R. Deziel;Weiguo Liu

  • Prevention of resistance: a goal for dose selection for antimicrobial agents.

    Unknown

  • Relationship between Fluoroquinolone Area under the Curve:Minimum Inhibitory Concentration Ratio and the Probability of Eradication of the Infecting Pathogen, in Patients with Nosocomial Pneumonia

    George L. Drusano;Sandra L. Preston;Cynthia Fowler;Michael Corrado

  • Application of a mathematical model to prevent in vivo amplification of antibiotic-resistant bacterial populations during therapy

    Nelson Jumbe;Arnold Louie;Robert Leary;Weiguo Liu

  • Application of Antimicrobial Pharmacodynamic Concepts into Clinical Practice: Focus on β-Lactam Antibiotics

    Thomas P. Lodise;Ben M. Lomaestro;George L. Drusano

  • Back to the Future: Using Aminoglycosides Again and How to Dose Them Optimally

    George L Drusano;Paul G Ambrose;Sujata M Bhavnani;Joseph S Bertino

  • Vancomycin: We Can't Get There From Here

    Nimish Patel;Manjunath P. Pai;Keith A. Rodvold;Ben Lomaestro

  • Daptomycin Exposure and the Probability of Elevations in the Creatine Phosphokinase Level: Data from a Randomized Trial of Patients with Bacteremia and Endocarditis

    Unknown

  • Pharmacodynamics of cefepime in patients with Gram-negative infections

    Vincent H. Tam;Peggy S. McKinnon;Ronda L. Akins;Michael J. Rybak

  • Use of Preclinical Data for Selection of a Phase II/III Dose for Evernimicin and Identification of a Preclinical MIC Breakpoint

    G. L. Drusano;S. L. Preston;C. Hardalo;R. Hare

  • Conserving antibiotics for the future: New ways to use old and new drugs from a pharmacokinetic and pharmacodynamic perspective

    Johan W Mouton;Paul G Ambrose;Rafael Canton;George L Drusano

Frequent Co-Authors

Thomas P. Lodise
Thomas P. Lodise Albany College of Pharmacy and Health Sciences
Jürgen B. Bulitta
Jürgen B. Bulitta St. Jude Children's Research Hospital
Sujata M. Bhavnani
Sujata M. Bhavnani University at Buffalo, State University of New York
William W. Hope
William W. Hope University of Liverpool
Tawanda Gumbo
Tawanda Gumbo Baylor University Medical Center
Robert A. Bonomo
Robert A. Bonomo Case Western Reserve University
Ulrike Holzgrabe
Ulrike Holzgrabe University of Würzburg
Ronald N. Jones
Ronald N. Jones JMI Laboratories
Thomas J. Walsh
Thomas J. Walsh Weill Cornell Medicine
Michael N. Dudley
Michael N. Dudley Qpex Biopharma

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