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Chemistry

D-Index
40
Citations
4896
World Ranking
17928
National Ranking
46

Overview

Gary B. Evans is affiliated with Victoria University of Wellington in New Zealand and has contributed to multiple fields focused primarily on biochemistry, genetics, molecular biology, and medicine.

The scientist's research encompasses various subfields including molecular biology, materials chemistry, infectious diseases, virology, as well as public health, environmental and occupational health.

The main topics addressed in their work include:

  • Crystallization and Solubility Studies
  • X-ray Diffraction in Crystallography
  • Biochemical and Molecular Research
  • HIV Research and Treatment
  • Mosquito-borne diseases and control
  • Viral Infections and Immunology Research
  • Interferon and immune responses

Notable publications authored or co-authored by Gary B. Evans include:

  • Viperin triggers ribosome collision-dependent translation inhibition to restrict viral replication, 2022, Molecular Cell
  • Combined Infection Control and Enhanced Osteogenic Differentiation Capacity on Additive Manufactured Ti-6Al-4V are Mediated via Titania Nanotube Delivery of Novel Biofilm Inhibitors, 2020, Advanced Materials Interfaces
  • Chemoenzymatic Synthesis of 3'-Deoxy-3',4'-didehydro-cytidine triphosphate (ddhCTP), 2023, ACS Bio & Med Chem Au
  • Narrow-Spectrum Antibiotic Targeting of the Radical SAM Enzyme MqnE in Menaquinone Biosynthesis, 2020, Biochemistry
  • Intracellular complexities of acquiring a new enzymatic function revealed by mass-randomisation of active-site residues, 2020, eLife

Frequent co-authors collaborating with Evans include:

  • Lawrence D. Harris
  • James M. Wood
  • Tyler L. Grove
  • Steven C. Almo
  • Scott A. Cameron

The scientific contributions also appear regularly in certain publication venues, with the highest number of works featured in The Cambridge Structural Database. Other common outlets include bioRxiv (Cold Spring Harbor Laboratory), Biochemistry, Molecular Cell, and ACS Bio & Med Chem Au.

Best Publications

  • Femtomolar Transition State Analogue Inhibitors of 5′-Methylthioadenosine/S-Adenosylhomocysteine Nucleosidase from Escherichia coli

    Vipender Singh;Gary B. Evans;Dirk H. Lenz;Jennifer M. Mason

  • Achieving the ultimate physiological goal in transition state analogue inhibitors for purine nucleoside phosphorylase.

    Andrzej Lewandowicz;Peter C. Tyler;Gary B. Evans;Richard H. Furneaux

  • Plasmodium falciparum purine nucleoside phosphorylase: crystal structures, immucillin inhibitors, and dual catalytic function.

    Wuxian Shi;Li Min Ting;Gregory A. Kicska;Andrzej Lewandowicz

  • Purine-less death in Plasmodium falciparum induced by immucillin-H, a transition state analogue of purine nucleoside phosphorylase

    Gregory A. Kicska;Peter C. Tyler;Gary B. Evans;Richard H. Furneaux

  • Targeting a novel Plasmodium falciparum purine recycling pathway with specific immucillins.

    Li Min Ting;Wuxian Shi;Andrzej Lewandowicz;Vipender Singh

  • Exploring Structure−Activity Relationships of Transition State Analogues of Human Purine Nucleoside Phosphorylase

    Gary B. Evans;Richard H. Furneaux;Andrzej Lewandowicz;Vern L. Schramm

  • Synthesis of second-generation transition state analogues of human purine nucleoside phosphorylase.

    Gary B. Evans;Richard H. Furneaux;Andrzej Lewandowicz;Vern L. Schramm

  • Transition state analogue inhibitors of purine nucleoside phosphorylase from Plasmodium falciparum.

    Gregory A. Kicska;Peter C. Tyler;Gary B. Evans;Richard H. Furneaux

  • Addition of Lithiated 9-Deazapurine Derivatives to a Carbohydrate Cyclic Imine: Convergent Synthesis of the Aza-C-nucleoside Immucillins

    Gary B. Evans;Richard H. Furneaux;Tracy L. Hutchison;Hollis S. Kezar

  • Synthesis of transition state analogue inhibitors for purine nucleoside phosphorylase and N-riboside hydrolases

    Gary B. Evans;Richard H. Furneaux;Graeme J. Gainsford;Vern L. Schramm

  • Azetidine based transition state analogue inhibitors of N-ribosyl hydrolases and phosphorylases.

    Gary B. Evans;Richard H. Furneaux;Ben Greatrex;Andrew S. Murkin

  • Synthesis of a transition state analogue inhibitor of purine nucleoside phosphorylase via the Mannich reaction.

    Gary B. Evans;Richard H. Furneaux;Peter C. Tyler;Vern L. Schramm

  • Growth and Metastases of Human Lung Cancer Are Inhibited in Mouse Xenografts by a Transition State Analogue of 5′-Methylthioadenosine Phosphorylase

    Indranil Basu;Joseph Locker;Maria B. Cassera;Thomas J. Belbin

  • Iminoribitol transition state analogue inhibitors of protozoan nucleoside hydrolases.

    Robert W. Miles;Peter C. Tyler;Gary B. Evans;Richard H. Furneaux

  • Four generations of transition-state analogues for human purine nucleoside phosphorylase

    Meng Chiao Ho;Wuxian Shi;Wuxian Shi;Agnes Rinaldo-Matthis;Agnes Rinaldo-Matthis;Peter C. Tyler

  • Structural rationale for the affinity of pico- and femtomolar transition state analogues of Escherichia coli 5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase.

    Jeffrey E. Lee;Vipender Singh;Gary B. Evans;Peter C. Tyler

  • Picomolar transition state analogue inhibitors of human 5'-methylthioadenosine phosphorylase and X-ray structure with MT-immucillin-A.

    Vipender Singh;Wuxian Shi;Gary B. Evans;Peter C. Tyler

  • Structure and Inhibition of a Quorum Sensing Target from Streptococcus pneumoniae

    Vipender Singh;Wuxian Shi;Steven C. Almo;Gary B. Evans

  • OVER-THE-BARRIER TRANSITION STATE ANALOGUES AND CRYSTAL STRUCTURE WITH MYCOBACTERIUM TUBERCULOSIS PURINE NUCLEOSIDE PHOSPHORYLASE

    Andrzej Lewandowicz;Wuxian Shi;Gary B. Evans;Peter C. Tyler

  • Picomolar inhibitors as transition-state probes of 5'-methylthioadenosine nucleosidases.

    Jemy A. Gutierrez;Minkui Luo;Vipender Singh;Lei Li

  • Atomic dissection of the hydrogen bond network for transition-state analogue binding to purine nucleoside phosphorylase

    Greg A. Kicska;Peter C. Tyler;Gary B. Evans;Richard H. Furneaux

Frequent Co-Authors

Peter C. Tyler
Peter C. Tyler Victoria University of Wellington
Richard H. Furneaux
Richard H. Furneaux Victoria University of Wellington
Vern L. Schramm
Vern L. Schramm Albert Einstein College of Medicine
Kami Kim
Kami Kim University of South Florida
Steven C. Almo
Steven C. Almo Albert Einstein College of Medicine
Stephen G. Davies
Stephen G. Davies University of Oxford
P. Lynne Howell
P. Lynne Howell University of Toronto
George W. J. Fleet
George W. J. Fleet University of Oxford
Tim B. F. Woodfield
Tim B. F. Woodfield University of Otago
George P. C. Salmond
George P. C. Salmond University of Cambridge

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