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Biology and Biochemistry

D-Index
48
Citations
12541
World Ranking
18235
National Ranking
582

Overview

Filomena Fezza is affiliated with the University of Rome Tor Vergata in Italy. Their research primarily falls within the field of Medicine, with a focus on Pharmacology, Surgery, Toxicology, Endocrinology, Diabetes and Metabolism, as well as Pediatrics, Perinatology and Child Health.

Fezza's main research topics include Cannabis and Cannabinoid Research, Pancreatic function and diabetes, Forensic Toxicology and Drug Analysis, Diet, Metabolism, and Disease, Alcohol Consumption and Health Effects, Biochemical effects in animals, and Prenatal Substance Exposure Effects.

Recent publications authored or co-authored by Fezza include:

  • The endocannabinoid hydrolase FAAH is an allosteric enzyme (2020, Scientific Reports)
  • Selective Fatty Acid Amide Hydrolase Inhibitors as Potential Novel Antiepileptic Agents (2021, ACS Chemical Neuroscience)
  • Advances in the discovery of fatty acid amide hydrolase inhibitors: what does the future hold? (2020, Expert Opinion on Drug Discovery)
  • Bisphenol A Deranges the Endocannabinoid System of Primary Sertoli Cells with an Impact on Inhibin B Production (2020, International Journal of Molecular Sciences)
  • Chemical Proteomics Reveals Off-Targets of the Anandamide Reuptake Inhibitor WOBE437 (2022, ACS Chemical Biology)

Fezza frequently publishes in the following venues:

  • Zenodo (CERN European Organization for Nuclear Research)
  • Scientific Reports
  • Cells
  • ACS Chemical Neuroscience
  • International Journal of Molecular Sciences

Collaborations form an important part of Fezza's research output. Among the most frequent co-authors are:

  • Mauro Maccarrone (20 joint publications)
  • Enrico Dainese (6 joint publications)
  • Beatrice Dufrusine (6 joint publications)
  • Domenico Fazio (6 joint publications)
  • Emanuele Criscuolo (6 joint publications)

Best Publications

  • Leptin-regulated endocannabinoids are involved in maintaining food intake

    Vincenzo Di Marzo;Sravan K. Goparaju;Lei Wang;Lei Wang;Jie Liu;Jie Liu

  • An endogenous capsaicin-like substance with high potency at recombinant and native vanilloid VR1 receptors

    Susan M. Huang;Tiziana Bisogno;Marcello Trevisani;Abdulmonem Al-Hayani

  • Endocannabinoid levels in rat limbic forebrain and hypothalamus in relation to fasting, feeding and satiation: stimulation of eating by 2-arachidonoyl glycerol

    Tim C Kirkham;Claire M Williams;Filomena Fezza;Vincenzo Di Marzo

  • Endocannabinoids control spasticity in a multiple sclerosis model

    D Baker;G Pryce;J L Croxford;P Brown

  • Activity-based protein profiling reveals off-target proteins of the FAAH inhibitor BIA 10-2474

    Annelot C. M. van Esbroeck;Antonius P. A. Janssen;Armand B. Cognetta;Daisuke Ogasawara

  • Anandamide inhibits metabolism and physiological actions of 2-arachidonoylglycerol in the striatum

    Mauro Maccarrone;Silvia Rossi;Monica Bari;Valentina De Chiara

  • Endocannabinoid signalling in the blood of patients with schizophrenia

    Nicola De Marchi;Luciano De Petrocellis;Pierangelo Orlando;Fabiana Daniele

  • Changes in endocannabinoid contents in the brain of rats chronically exposed to nicotine, ethanol or cocaine.

    Sara González;Maria Grazia Cascio;Javier Fernández-Ruiz;Filomena Fezza

  • Cannabinoid CB1‐receptor mediated regulation of gastrointestinal motility in mice in a model of intestinal inflammation

    Angelo A Izzo;Filomena Fezza;Raffaele Capasso;Tiziana Bisogno

  • Cannabinoid CB2 receptor ligand profiling reveals biased signalling and off-target activity

    Marjolein Soethoudt;Uwe Grether;Juergen Fingerle;Travis W. Grim

  • Lipid Rafts Control Signaling of Type-1 Cannabinoid Receptors in Neuronal Cells IMPLICATIONS FOR ANANDAMIDE-INDUCED APOPTOSIS

    Monica Bari;Natalia Battista;Filomena Fezza;Alessandro Finazzi-Agrò

  • The endocannabinoid system is dysregulated in multiple sclerosis and in experimental autoimmune encephalomyelitis.

    Diego Centonze;Monica Bari;Silvia Rossi;Chiara Prosperetti

  • Characterization of the endocannabinoid system in boar spermatozoa and implications for sperm capacitation and acrosome reaction.

    Mauro Maccarrone;Barbara Barboni;Andrea Paradisi;N. Nicola Bernabò

  • Exogenous Anandamide Protects Rat Brain against Acute Neuronal Injury In Vivo

    M. van der Stelt;W. B. Veldhuis;G. W. van Haaften;F. Fezza

  • Lipopolysaccharide downregulates fatty acid amide hydrolase expression and increases anandamide levels in human peripheral lymphocytes.

    M Maccarrone;L De Petrocellis;M Bari;F Fezza

  • Neuroprotection by the Endogenous Cannabinoid Anandamide and Arvanil against In Vivo Excitotoxicity in the Rat: Role of Vanilloid Receptors and Lipoxygenases

    W. B. Veldhuis;M. van der Stelt;M. W. Wadman;G. van Zadelhoff

  • Endocannabinoids, related compounds and their metabolic routes.

    Filomena Fezza;Monica Bari;Rita Florio;Emanuela Talamonti

  • High endogenous cannabinoid levels in the cerebrospinal fluid of untreated Parkinson's disease patients.

    Antonio Pisani;Filomena Fezza;Salvatore Galati;Natalia Battista

  • Low fatty acid amide hydrolase and high anandamide levels are associated with failure to achieve an ongoing pregnancy after IVF and embryo transfer.

    Mauro Maccarrone;Tiziana Bisogno;Herbert Valensise;Natalia Lazzarin

  • N-Arachidonoyl-Dopamine Tunes Synaptic Transmission onto Dopaminergic Neurons by Activating both Cannabinoid and Vanilloid Receptors

    Silvia Marinelli;Vincenzo Di Marzo;Fulvio Florenzano;Filomena Fezza

Frequent Co-Authors

Mauro Maccarrone
Mauro Maccarrone University of L'Aquila
Vincenzo Di Marzo
Vincenzo Di Marzo National Research Council (CNR)
Alessandro Finazzi-Agrò
Alessandro Finazzi-Agrò University of Rome Tor Vergata
Tiziana Bisogno
Tiziana Bisogno National Research Council (CNR)
Javier Fernández-Ruiz
Javier Fernández-Ruiz Complutense University of Madrid
Diego Centonze
Diego Centonze University of Rome Tor Vergata
Giuseppe Valacchi
Giuseppe Valacchi North Carolina State University
Giorgio Bernardi
Giorgio Bernardi University of Rome Tor Vergata
Sandra Gemma
Sandra Gemma University of Siena
Giuseppe Campiani
Giuseppe Campiani University of Siena

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