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Microbiology

D-Index
44
Citations
7298
World Ranking
5143
National Ranking
125

Overview

Dominique Garcin is affiliated with the University of Geneva in Switzerland and focuses on research primarily in the fields of medicine, immunology, and microbiology. Their work broadly addresses areas within immunology, infectious diseases, epidemiology, molecular biology, and cardiovascular medicine.

The main topics of Garcin's research include interferon and immune responses, viral infections and vectors, RNA modifications and cancer, viral infections and immunology research, viral gastroenteritis research and epidemiology, cervical cancer and HPV research, and NF-κB signaling pathways.

Recent publications authored or co-authored by Garcin include:

  • "Nonsegmented Negative-Sense RNA Viruses Utilize N 6 -Methyladenosine (m 6 A) as a Common Strategy To Evade Host Innate Immunity," 2021, Journal of Virology
  • "High-Risk Mucosal Human Papillomavirus 16 (HPV16) E6 Protein and Cutaneous HPV5 and HPV8 E6 Proteins Employ Distinct Strategies To Interfere with Interferon Regulatory Factor 3-Mediated Beta Interferon Expression," 2022, Journal of Virology
  • "Identifying enhancers of innate immune signaling as broad-spectrum antivirals active against emerging viruses," 2022, Cell chemical biology
  • "Complete genome sequence of Tacaribe virus," 2020, Archives of Virology
  • "NCoR1 fine-tunes type-I IFN response in cDC1 dendritic cells by directly regulating Myd88-IRF7 axis under TLR9," 2020, European Journal of Immunology

Frequent co-authors include:

  • Mark E. Peeples
  • Mijia Lu
  • Miaoge Xue
  • Haitao Wang
  • Elizabeth L. Kairis

Scientific contributions by Garcin have been published extensively in leading venues, with multiple works appearing in these journals:

  • Journal of Virology
  • Cell chemical biology
  • Archives of Virology
  • European Journal of Immunology
  • The Journal of Immunology

Best Publications

  • Paramyxovirus RNA Synthesis and the Requirement for Hexamer Genome Length: the Rule of Six Revisited

    Daniel Kolakofsky;Thierry Pelet;Dominique Garcin;Stéphane Hausmann

  • Mitochondrial dynamics regulate the RIG-I-like receptor antiviral pathway

    Céline Castanier;Dominique Garcin;Aimé Vazquez;Damien Arnoult

  • A highly recombinogenic system for the recovery of infectious Sendai paramyxovirus from cDNA: generation of a novel copy-back nondefective interfering virus.

    Dominique Garcin;Thierry Pelet;Philippe Calain;Laurent Roux

  • The 5' ends of Hantaan virus (Bunyaviridae) RNAs suggest a prime-and-realign mechanism for the initiation of RNA synthesis.

    Dominique Garcin;M Lezzi;M Dobbs;R M Elliott

  • Sendai Virus C Proteins Counteract the Interferon-Mediated Induction of an Antiviral State

    Dominique Garcin;Patrizia Latorre;Daniel Kolakofsky

  • IFN-λ prevents influenza virus spread from the upper airways to the lungs and limits virus transmission

    Jonas Klinkhammer;Daniel Schnepf;Liang Ye;Marilena Schwaderlapp

  • Sendai virus defective-interfering genomes and the activation of interferon-beta.

    Laura Eve Strahle;Dominique Garcin;Daniel Kolakofsky

  • Paramyxovirus mRNA editing, the "rule of six" and error catastrophe: a hypothesis.

    Daniel Kolakofsky;Laurent Roux;Dominique Garcin;Rob W. H. Ruigrok

  • MAVS ubiquitination by the E3 ligase TRIM25 and degradation by the proteasome is involved in type I interferon production after activation of the antiviral RIG-I-like receptors

    Céline Castanier;Naima Zemirli;Naima Zemirli;Alain Portier;Alain Portier;Dominique Garcin

  • The Sendai paramyxovirus accessory C proteins inhibit viral genome amplification in a promoter-specific fashion.

    Tamarra Leigh Cadd;Dominique Garcin;Caroline Tapparel;M Itoh

  • All four Sendai Virus C proteins bind Stat1, but only the larger forms also induce its mono-ubiquitination and degradation.

    Dominique Garcin;Jean-Baptiste Marq;Laura Eve Strahle;Philippe Le Mercier

  • The Versatility of Paramyxovirus RNA Polymerase Stuttering

    Stéphane Hausmann;Dominique Garcin;Christophe Delenda;Daniel Kolakofsky

  • Activation of the Beta Interferon Promoter by Unnatural Sendai Virus Infection Requires RIG-I and Is Inhibited by Viral C Proteins

    Laura Eve Strahle;Jean-Baptiste Marq;Albert Brini;Stéphane Hausmann

  • Sendai virus trailer RNA binds TIAR, a cellular protein involved in virus-induced apoptosis

    Frédéric Iseni;Dominique Garcin;Machiko Nishio;Nancy Kedersha

  • Severe viral respiratory infections in children with IFIH1 loss-of-function mutations

    Samira Asgari;Samira Asgari;Luregn J. Schlapbach;Luregn J. Schlapbach;Stéphanie Anchisi;Christian Hammer;Christian Hammer

  • Hepatitis C Virus Controls Interferon Production through PKR Activation

    Noëlla Arnaud;Stéphanie Dabo;Patrick Maillard;Agata Budkowska

  • Viral DNA polymerase scanning and the gymnastics of Sendai virus RNA synthesis.

    Daniel Kolakofsky;Philippe Le Mercier;Frédéric Iseni;Dominique Garcin

  • Nontemplated bases at the 5' ends of Tacaribe virus mRNAs

    Ramasamy Raju;Latha Raju;David Lynn Hacker;Dominique Garcin

  • A novel mechanism for the initiation of Tacaribe arenavirus genome replication.

    Dominique Garcin;Daniel Kolakofsky

  • A point mutation in the Sendai virus accessory C proteins attenuates virulence for mice, but not virus growth in cell culture.

    Dominique Garcin;Masae Itoh;Daniel Kolakofsky

  • A highly recombinogenic systemfortherecoveryof infectious Sendai paramyxovirus fromcDNA: generation ofa novelcopy-back nondefective interfering virus

    Dominique Garcin;Thierry Pelet;Philippe Calain;Laurent Roux

Frequent Co-Authors

Daniel Kolakofsky
Daniel Kolakofsky University of Geneva
Damien Arnoult
Damien Arnoult Grenoble Alpes University
Caroline Tapparel
Caroline Tapparel University of Geneva
Hans Acha-Orbea
Hans Acha-Orbea University of Lausanne
Richard W. Compans
Richard W. Compans Emory University
Peter Staeheli
Peter Staeheli University of Freiburg
Rune Hartmann
Rune Hartmann Aarhus University
Mark E. Peeples
Mark E. Peeples The Ohio State University
Gyan P. Mishra
Gyan P. Mishra Indian Agricultural Research Institute
Maciej Wiznerowicz
Maciej Wiznerowicz Poznan University of Medical Sciences

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