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David M. Lyerly

David M. Lyerly

D-Index & Metrics

Microbiology

D-Index
53
Citations
10025
World Ranking
4096
National Ranking
1587

Overview

David M. Lyerly is affiliated with Virginia Tech in the United States, with a research focus spanning medicine and biochemistry, genetics, and molecular biology. Their work primarily addresses infectious diseases and molecular biology, with notable contributions in epidemiology, gastroenterology, and surgery.

Their research extensively covers topics such as Clostridium difficile and Clostridium perfringens research, gut microbiota and health, microscopic colitis, gastrointestinal motility and disorders, and Helicobacter pylori-related gastroenterology studies.

Recent publications by David M. Lyerly include the following works:

  • Clostridioides difficile Infection: The Challenge, Tests, and Guidelines, 2020, ACS Infectious Diseases
  • Binary Toxin Expression by Clostridioides difficile Is Associated With Worse Disease, 2022, Open Forum Infectious Diseases
  • Binary toxin expression by Clostridioides difficile is associated with worse disease, 2021, bioRxiv (Cold Spring Harbor Laboratory)

David M. Lyerly has collaborated frequently with several co-authors, including Robert J. Carman, Mary K. Young, Jhansi L. Leslie, Gregory R. Madden, and David B. Stewart.

Their research findings have been published in multiple venues, including:

  • Open Forum Infectious Diseases
  • ACS Infectious Diseases
  • bioRxiv (Cold Spring Harbor Laboratory)

Best Publications

  • Clostridium difficile: its disease and toxins.

    D M Lyerly;H C Krivan;T D Wilkins

  • Effects of Clostridium difficile toxins given intragastrically to animals.

    D M Lyerly;K E Saum;D K MacDonald;T D Wilkins

  • Fecal lactoferrin is a sensitive and specific marker in identifying intestinal inflammation

    Sunanda V Kane;William J Sandborn;Paul A Rufo;Anna Zholudev

  • Molecular characterization of the Clostridium difficile toxin A gene.

    C H Dove;S Z Wang;S B Price;C J Phelps

  • Biological activities of toxins A and B of Clostridium difficile.

    D M Lyerly;D E Lockwood;S H Richardson;T D Wilkins

  • Characterization of a Toxin A-Negative, Toxin B-Positive Strain of Clostridium difficile Responsible for a Nosocomial Outbreak of Clostridium difficile-Associated Diarrhea

    Michelle J. Alfa;Amin Kabani;David Lyerly;Scott Moncrief

  • Diagnosis of Amebic Liver Abscess and Intestinal Infection with the TechLab Entamoeba histolytica II Antigen Detection and Antibody Tests

    Rashidul Haque;Nasir Uddin Mollah;Ibne Karim M. Ali;Khorshed Alam

  • Binary Toxin–Producing, Large Clostridial Toxin–Negative Clostridium difficile Strains Are Enterotoxic but Do Not Cause Disease in Hamsters

    Barbara Geric;Robert J. Carman;Maja Rupnik;Christopher W. Genheimer

  • The enterotoxin of Bacteroides fragilis is a metalloprotease.

    J S Moncrief;R Obiso;L A Barroso;J J Kling

  • Clostridium difficile Testing: after 20 Years, Still Challenging

    Tracy D. Wilkins;David M. Lyerly

  • Passive immunization of hamsters against disease caused by Clostridium difficile by use of bovine immunoglobulin G concentrate.

    D M Lyerly;E F Bostwick;S B Binion;T D Wilkins

  • Estimating the impact of amebiasis on health.

    W.A Petri;R Haque;D Lyerly;R.R Vines

  • Enzyme-linked immunosorbent assay for Clostridium difficile toxin A.

    D M Lyerly;N M Sullivan;T D Wilkins

  • Effects of Clostridium difficile toxins A and B in rabbit small and large intestine in vivo and on cultured cells in vitro.

    A. A. M. Lima;D. M. Lyerly;T. D. Wilkins;D. J. Innes

  • Protection against experimental pseudomembranous colitis in gnotobiotic mice by use of monoclonal antibodies against Clostridium difficile toxin A.

    G Corthier;M C Muller;T D Wilkins;D Lyerly

  • The Enterotoxic Clostridia

    Bruce A. McClane;Francisco A. Uzal;Mariano E. Fernandez Miyakawa;David Lyerly

  • Characterization of a toxin A-negative, toxin B-positive strain of Clostridium difficile.

    D M Lyerly;L A Barroso;T D Wilkins;C Depitre

  • Entamoeba histolytica and Entamoeba dispar Infection in Children in Bangladesh

    Rashidul Haque;A. S. G. Faruque;Pauline Hahn;David M. Lyerly

  • Evaluation of formalin-inactivated Clostridium difficile vaccines administered by parenteral and mucosal routes of immunization in hamsters.

    J F Torres;D M Lyerly;J E Hill;T P Monath

  • Characterization of toxins A and B of Clostridium difficile with monoclonal antibodies.

    D M Lyerly;C J Phelps;J Toth;T D Wilkins

  • Recombinant toxin A and toxin B protein carrier for polysaccharide conjugate vaccines

    Tracy Wilkins;David Lyerly;J. Moncrief;Danka Pavliakova

Frequent Co-Authors

Tracy D. Wilkins
Tracy D. Wilkins Virginia Tech
William A. Petri
William A. Petri University of Virginia
Dale N. Gerding
Dale N. Gerding Veterans Health Administration
Rashidul Haque
Rashidul Haque International Centre for Diarrhoeal Disease Research
John L. Johnson
John L. Johnson Virginia Tech
Eric R. Houpt
Eric R. Houpt University of Virginia
Stuart Johnson
Stuart Johnson Loyola University Chicago
Richard L. Guerrant
Richard L. Guerrant University of Virginia
Thomas P. Monath
Thomas P. Monath Crozet BioPharma
Abraham L. Sonenshein
Abraham L. Sonenshein Tufts University

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