Daria J. Hazuda

Best Publications

• Inhibitors of Strand Transfer That Prevent Integration and Inhibit HIV-1 Replication in Cells

  Daria J. Hazuda;Peter Felock;Marc Witmer;Abigail Wolfe

  1478
  Citations

• Administration of vorinostat disrupts HIV-1 latency in patients on antiretroviral therapy

  N. M. Archin;A. L. Liberty;A. D. Kashuba;S. K. Choudhary

  1372
  Citations

• HIV-1 Antiretroviral Drug Therapy

  Eric J. Arts;Daria J. Hazuda

  1330
  Citations

• The challenge of finding a cure for HIV infection.

  Douglas D. Richman;David M. Margolis;Martin Delaney;Warner C. Greene

  1068
  Citations

• Genome-Scale RNAi Screen for Host Factors Required for HIV Replication

  Honglin Zhou;Min Xu;Qian Huang;Adam T. Gates

  957
  Citations

• Raltegravir with Optimized Background Therapy for Resistant HIV-1 Infection

  Roy T. Steigbigel;David A. Cooper;Princy N. Kumar;Joseph E. Eron

  913
  Citations

• Discovery of Raltegravir, a Potent, Selective Orally Bioavailable HIV-Integrase Inhibitor for the Treatment of HIV-AIDS Infection

  Vincenzo Summa;Alessia Petrocchi;Fabio Bonelli;Benedetta Crescenzi

  744
  Citations

• P-TEFb kinase is required for HIV Tat transcriptional activation in vivo and in vitro.

  Helena S.Y. Mancebo;Gary Lee;John Flygare;Joanne Tomassini

  708
  Citations

• Subgroup and resistance analyses of raltegravir for resistant HIV-1 infection.

  David A. Cooper;Roy T. Steigbigel;Jose M. Gatell;Jurgen K. Rockstroh

  611
  Citations

• Diketo acid inhibitor mechanism and HIV-1 integrase: implications for metal binding in the active site of phosphotransferase enzymes.

  Jay A. Grobler;Kara Stillmock;Binghua Hu;Marc Witmer

  596
  Citations

• Activation of HIV transcription with short-course vorinostat in HIV-infected patients on suppressive antiretroviral therapy.

  Julian H. Elliott;Fiona Wightman;Ajantha Solomon;Khader Ghneim

  565
  Citations

• Host Cell Factors in HIV Replication: Meta-Analysis of Genome-Wide Studies

  Frederic D. Bushman;Nirav Malani;Jason Fernandes;Jason Fernandes;Iván D'Orso;Iván D'Orso

  524
  Citations

• HIV-1 integrase inhibitors that compete with the target DNA substrate define a unique strand transfer conformation for integrase

  Amy S. Espeseth;Peter Felock;Abigail Wolfe;Marc Witmer

  435
  Citations

• Expression of Latent HIV Induced by the Potent HDAC Inhibitor Suberoylanilide Hydroxamic Acid

  Nancie M. Archin;Amy Espeseth;Daniel Parker;Manzoor Cheema

  420
  Citations

• A naphthyridine carboxamide provides evidence for discordant resistance between mechanistically identical inhibitors of HIV-1 integrase.

  Daria J. Hazuda;Neville J. Anthony;Robert P. Gomez;Samson M. Jolly

  414
  Citations

• Integrase Inhibitors and Cellular Immunity Suppress Retroviral Replication in Rhesus Macaques

  Daria J. Hazuda;Steven D. Young;James P. Guare;Neville J. Anthony

  378
  Citations

• Design and Synthesis of 8-Hydroxy-[1,6]Naphthyridines as Novel Inhibitors of HIV-1 Integrase in Vitro and in Infected Cells

  Linghang Zhuang;John S. Wai;Mark W. Embrey;Thorsten E. Fisher

  370
  Citations

• 4-Aryl-2,4-dioxobutanoic acid inhibitors of HIV-1 integrase and viral replication in cells.

  John S. Wai;Melissa S. Egbertson;Linda S. Payne;Thorsten E. Fisher

  323
  Citations

• Latency reversal and viral clearance to cure HIV-1

  David M. Margolis;J. Victor Garcia;Daria J. Hazuda;Barton F. Haynes

  299
  Citations

• A Novel Assay to Measure the Magnitude of the Inducible Viral Reservoir in HIV-infected Individuals

  Francesco Andrea Procopio;Rémi Fromentin;Deanna A. Kulpa;Jessica H. Brehm

  293
  Citations