Bruce G. Jenkins

Best Publications

• A novel gene containing a trinucleotide repeat that is expanded and unstable on Huntington's disease chromosomes. The Huntington's Disease Collaborative Research Group.

  M Shah;N Datson;L Srinidhi;VP Stanton

  4892
  Citations

• Embryonic stem cells develop into functional dopaminergic neurons after transplantation in a Parkinson rat model

  Lars M. Björklund;Rosario Sánchez-Pernaute;Sangmi Chung;Therese Andersson;Therese Andersson

  1642
  Citations

• Trinucleotide repeat length instability and age of onset in Huntington's disease

  M Duyao;C Ambrose;R Myers;A Novelletto

  1385
  Citations

• Regional and progressive thinning of the cortical ribbon in Huntington's disease

  H. D. Rosas;A. K. Liu;S. Hersch;M. Glessner

  1255
  Citations

• Neurochemical and histologic characterization of striatal excitotoxic lesions produced by the mitochondrial toxin 3-nitropropionic acid

  MF Beal;E Brouillet;BG Jenkins;RJ Ferrante

  1230
  Citations

• Evidence for irnnairment of energy metabofism in vivo in Huntington's disease using localized 1H NMR spectroscopy

  B. G. Jenkins;W. J. Koroshetz;M. F. Beal;B. R. Rosen

  672
  Citations

• Neuroprotective effects of creatine in a transgenic mouse model of Huntington's disease.

  Robert J. Ferrante;Ole A. Andreassen;Bruce G. Jenkins;Alpaslan Dedeoglu

  656
  Citations

• Evidence for more widespread cerebral pathology in early HD: An MRI-based morphometric analysis

  H. D. Rosas;W. J. Koroshetz;Y. I. Chen;C. Skeuse

  595
  Citations

• Energy metabolism defects in Huntington's disease and effects of coenzyme Q10

  Koroshetz Wj;Jenkins Bg;Rosen Br;Beal Mf

  585
  Citations

• Age-dependent vulnerability of the striatum to the mitochondrial toxin 3-nitropropionic acid.

  E. Brouillet;B. G. Jenkins;B. T. Hyman;R. J. Ferrante

  517
  Citations

• NEUROPROTECTIVE EFFECTS OF CREATINE AND CYCLOCREATINE IN ANIMAL MODELS OF HUNTINGTON'S DISEASE

  R T Matthews;L Yang;B G Jenkins;R J Ferrante

  509
  Citations

• Therapeutic Effects of Coenzyme Q10 and Remacemide in Transgenic Mouse Models of Huntington's Disease

  Robert J. Ferrante;Robert J. Ferrante;Ole A. Andreassen;Alpaslan Dedeoglu;Alpaslan Dedeoglu;Kimberly L. Ferrante

  486
  Citations

• Involvement of free radicals in excitotoxicity in vivo

  Schulz Jb;Henshaw Dr;Siwek D;Jenkins Bg

  476
  Citations

• Age‐Dependent Striatal Excitotoxic Lesions Produced by the Endogenous Mitochondrial Inhibitor Malonate

  M F Beal;E Brouillet;B Jenkins;R Henshaw

  439
  Citations

• Gadolinium chelates with weak binding to serum proteins. A new class of high-efficiency, general purpose contrast agents for magnetic resonance imaging

  Friedrich M. Cavagna;Fabio Maggioni;Paolo M. Castelli;Massimo Dapra

  395
  Citations

• Creatine in Huntington disease is safe, tolerable, bioavailable in brain and reduces serum 8OH2'dG.

  S. M. Hersch;S. Gevorkian;K. Marder;C. Moskowitz

  374
  Citations

• Creatine Increases Survival and Delays Motor Symptoms in a Transgenic Animal Model of Huntington's Disease

  O A Andreassen;A Dedeoglu;R J Ferrante;R J Ferrante;B G Jenkins

  358
  Citations

• Detection of dopaminergic neurotransmitter activity using pharmacologic MRI: correlation with PET, microdialysis, and behavioral data

  Yin Ching I. Chen;Wendy R. Galpern;Anna‐Liisa Brownell;Russell T. Matthews

  355
  Citations

• Blockade of neuronal nitric oxide synthase protects against excitotoxicity in vivo.

  J B Schulz;R T Matthews;B G Jenkins;R J Ferrante

  340
  Citations

• Coenzyme Q10 and nicotinamide block striatal lesions produced by the mitochondrial toxin malonate

  M F Beal;D R Henshaw;B G Jenkins;B R Rosen

  280
  Citations

• 1H NMR spectroscopy studies of Huntington's disease Correlations with CAG repeat numbers

  B. G. Jenkins;H. D. Rosas;Y.-C. I. Chen;T. Makabe

  271
  Citations

• Nonlinear decrease over time in N-acetyl aspartate levels in the absence of neuronal loss and increases in glutamine and glucose in transgenic Huntington's disease mice.

  Bruce G. Jenkins;Peter Klivenyi;Ekkehard Kustermann;Ole A. Andreassen

  251
  Citations