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D-Index & Metrics

Biology and Biochemistry

D-Index
51
Citations
14641
World Ranking
16966
National Ranking
1337

Overview

Andrew J. Doig is affiliated with the University of Manchester in the United Kingdom. Their research spans several fields, primarily focusing on biochemistry, genetics, and molecular biology, with additional contributions in medicine. The scientist's work encompasses multiple subfields including molecular biology, physiology, neurology, genetics, and biological psychiatry.

The main topics of their research include:

  • Alzheimer's disease research and treatments
  • Protein structure and dynamics
  • Bioinformatics and genomic networks
  • Heat shock proteins research
  • RNA research and splicing
  • Machine learning in bioinformatics
  • Gene expression and cancer classification

Andrew J. Doig has contributed to a number of significant publications. Some recent papers include:

  • Amyloid Oligomers: A Joint Experimental/Computational Perspective on Alzheimer's Disease, Parkinson's Disease, Type II Diabetes, and Amyotrophic Lateral Sclerosis, 2021, Chemical Reviews
  • Viral Involvement in Alzheimer's Disease, 2021, ACS Chemical Neuroscience
  • Raman Spectroscopy to Monitor Post-Translational Modifications and Degradation in Monoclonal Antibody Therapeutics, 2020, Analytical Chemistry
  • Quantification of protein glycation using vibrational spectroscopy, 2020, The Analyst
  • Glycine rich segments adopt polyproline II helices: Implications for biomolecular condensate formation, 2021, Archives of Biochemistry and Biophysics

Frequent collaboration is a notable aspect of their work. Regular co-authors include Bethan S. McAvan, Amro Safadi, Simon C. Lovell, Bikash R. Sahoo, and Peter Faller.

The scientist has published frequently in venues such as bioRxiv (Cold Spring Harbor Laboratory), Scientific Reports, Chemical Reviews, ACS Chemical Neuroscience, and Analytical Chemistry.

Best Publications

  • Drug repurposing: progress, challenges and recommendations

    Sudeep Pushpakom;Francesco Iorio;Patrick A Eyers;K Jane Escott

  • Amyloid β Protein and Alzheimer’s Disease: When Computer Simulations Complement Experimental Studies

    Jessica Nasica-Labouze;Phuong H. Nguyen;Fabio Sterpone;Olivia Berthoumieu

  • Amyloid oligomers: A joint experimental/computational perspective on Alzheimer's disease, Parkinson's disease, type II diabetes, and amyotrophic lateral sclerosis

    Phuong H. Nguyen;Ayyalusamy Ramamoorthy;Bikash R. Sahoo;Jie Zheng

  • Distinguishing enzyme structures from non-enzymes without alignments.

    Paul D. Dobson;Andrew J. Doig

  • N- and C-capping preferences for all 20 amino acids in alpha-helical peptides.

    Andrew J. Doig;Robert L. Baldwin

  • Side-chain conformational entropy in protein folding

    Andrew J. Doig;Michael J. E. Sternberg

  • Properties and identification of human protein drug targets

    Tala M. Bakheet;Andrew J. Doig

  • Inhibition of protein aggregation and amyloid formation by small molecules.

    Andrew J Doig;Philippe Derreumaux;Philippe Derreumaux

  • Inhibition of toxicity in the beta-amyloid peptide fragment beta -(25-35) using N-methylated derivatives: a general strategy to prevent amyloid formation.

    Eleri Hughes;Ron M. Burke;Andrew J. Doig

  • Helix capping propensities in peptides parallel those in proteins

    Avijit Chakrabartty;Andrew J. Doig;Robert L. Baldwin

  • Toward the semiquantitative estimation of binding constants guides for peptide peptide binding in aqueous solution

    Dudley H. Williams;Jonathan P. L. Cox;Andrew J. Doig;Mark Gardner

  • Is polyproline II helix the killer conformation? A Raman optical activity study of the amyloidogenic prefibrillar intermediate of human lysozyme.

    Ewan W Blanch;Ludmilla A Morozova-Roche;Duncan A.E Cochran;Andrew J Doig

  • N-Methylated Peptide Inhibitors of β-Amyloid Aggregation and Toxicity. Optimization of the Inhibitor Structure†

    Nicoleta Kokkoni;Kelvin Stott;Hozefa Amijee;Jody M. Mason

  • Determination of free energies of N-capping in alpha-helices by modification of the Lifson-Roig helix-coil therapy to include N- and C-capping.

    Andrew J. Doig;Avijit Chakrabartty;Tod M. Klingler;Robert L. Baldwin

  • Is the hydrophobic effect stabilizing or destabilizing in proteins? The contribution of disulphide bonds to protein stability.

    Andrew J. Doig;Dudley H. Williams

  • Why Is Research on Amyloid-β Failing to Give New Drugs for Alzheimer’s Disease?

    Andrew J. Doig;Maria P. del Castillo-Frias;Olivia Berthoumieu;Olivia Berthoumieu;Bogdan Tarus

  • Predicting enzyme class from protein structure without alignments

    Paul D. Dobson;Andrew J. Doig

  • Design strategies for anti-amyloid agents.

    Jody M Mason;Nicoleta Kokkoni;Kelvin Stott;Andrew J Doig

  • Binding energy of an amide-amide hydrogen bond in aqueous and nonpolar solvents

    Andrew J. Doig;Dudley H. Williams

  • Effect of phosphorylation on α-helix stability as a function of position

    Charles D. Andrew;Jim Warwicker;Gareth R. Jones;Andrew J. Doig

Frequent Co-Authors

Philippe Derreumaux
Philippe Derreumaux Ton Duc Thang University
Ewan W. Blanch
Ewan W. Blanch RMIT University
Peter Faller
Peter Faller University of Strasbourg
Dudley H. Williams
Dudley H. Williams University of Cambridge
Robert L. Baldwin
Robert L. Baldwin Stanford University
Simon J. Hubbard
Simon J. Hubbard Manchester Academic Health Science Centre
Claire Wilson
Claire Wilson University of Glasgow
Yu-Dong Cai
Yu-Dong Cai Shanghai University
Avijit Chakrabartty
Avijit Chakrabartty University of Toronto
Philip J. R. Day
Philip J. R. Day University of Manchester

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