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Molecular Biology

D-Index
85
Citations
25081
World Ranking
855
National Ranking
68

Overview

Alfred Nordheim is affiliated with the University of Tübingen in Germany. Their research spans several areas within biochemistry, genetics, molecular biology, and medicine, focusing on molecular biology and related subfields such as neurology, immunology and allergy, pharmacology, and cell biology.

The scientist's recent publications address topics in vascular biology, cancer gene regulation, and cardiovascular research. Notable recent papers include:

  • Mural Cell SRF Controls Pericyte Migration, Vessel Patterning and Blood Flow, 2022, Circulation Research
  • Serum Response Factor (SRF) Drives the Transcriptional Upregulation of the MDM4 Oncogene in HCC, 2021, Cancers
  • Endothelial LATS2 is a suppressor of bone marrow fibrosis, 2024, Nature Cardiovascular Research
  • Age-Associated Changes in Endothelial Transcriptome and Epigenetic Landscapes Correlate With Elevated Risk of Cerebral Microbleeds, 2023, Journal of the American Heart Association
  • De novo identification of maximally deregulated subnetworks based on multi-omics data with DeRegNet, 2022, BMC Bioinformatics

Their work touches on a variety of research topics, including:

  • Kruppel-like factors research
  • Cell Adhesion Molecules Research
  • Barrier Structure and Function Studies
  • Apelin-related biomedical research
  • Intracerebral and Subarachnoid Hemorrhage Research
  • Bioinformatics and Genomic Networks
  • Gene expression and cancer classification

Frequent collaborators in their research include Michael M. Orlich, Ralf H. Adams, Vithiyanjali Sothilingam, Mathias W. Seeliger, and Robert Geffers.

The primary publication venues for Alfred Nordheim's work are diverse, encompassing:

  • bioRxiv (Cold Spring Harbor Laboratory)
  • Circulation Research
  • Nature Cardiovascular Research
  • Cancers
  • Journal of the American Heart Association

The scientist's research integrates molecular and cellular biology approaches to investigate vascular patterning, transcriptional regulation in cancer, and cardiovascular disease mechanisms. Their studies contribute to understanding gene regulation in health and disease, utilizing bioinformatics and multi-omics methods to identify deregulated molecular networks.

Best Publications

  • THE CHEMISTRY AND BIOLOGY OF LEFT-HANDED Z-DNA

    Alexander Rich;Alfred Nordheim;Andrew H.-J. Wang

  • Linking actin dynamics and gene transcription to drive cellular motile functions.

    Eric N. Olson;Alfred Nordheim

  • Id genes are direct targets of bone morphogenetic protein induction in embryonic stem cells.

    Angela Hollnagel;Verena Oehlmann;Joachim Heymer;Ulrich Rüther

  • Activation of ternary complex factor Elk-1 by MAP kinases

    Ralf Janknecht;Wolfram H. Ernst;Vera Pingoud;Alfred Nordheim

  • Myocardin and ternary complex factors compete for SRF to control smooth muscle gene expression

    Zhigao Wang;Da Zhi Wang;Da Zhi Wang;Dirk Hockemeyer;John McAnally

  • Involvement of growth factor receptors in the mammalian UVC response.

    Christoph Sachsenmaier;Adriana Radler-Pohl;Raymund Zinck;Alfred Nordheim

  • Potentiation of serum response factor activity by a family of myocardin-related transcription factors.

    Da Zhi Wang;Shijie Li;Dirk Hockemeyer;Lillian Sutherland

  • Serum response factor is essential for mesoderm formation during mouse embryogenesis.

    S. Arsenian;B. Weinhold;M. Oelgeschläger;U. Rüther

  • WIPI-1alpha (WIPI49), a member of the novel 7-bladed WIPI protein family, is aberrantly expressed in human cancer and is linked to starvation-induced autophagy

    Tassula Proikas-Cezanne;Scott Waddell;Anja Gaugel;Tancred Frickey

  • Antibodies to left-handed Z-DNA bind to interband regions of Drosophila polytene chromosomes

    Alfred Nordheim;Mary Lou Pardue;Eileen M. Lafer;Achim Möller

  • Requirement for serum response factor for skeletal muscle growth and maturation revealed by tissue-specific gene deletion in mice

    Shijie Li;Michael P. Czubryt;John McAnally;Rhonda S Bassel-Duby

  • Flipping of cloned d(pCpG)n.d(pCpG)n DNA sequences from right- to left-handed helical structure by salt, Co(III), or negative supercoiling

    L J Peck;A Nordheim;A Rich;J C Wang

  • The sequence (dC-dA)n X (dG-dT)n forms left-handed Z-DNA in negatively supercoiled plasmids

    Alfred Nordheim;Alexander Rich

  • Negatively Supercoiled Plasmids Contain Left-handed Z-DNA Segments As Detected by Specific Antibody Binding

    Alfred Nordheim;Eileen M. Lafer;Lawrence J. Peck;James C. Wang

  • Comparative proteome analysis of Staphylococcus aureus biofilm and planktonic cells and correlation with transcriptome profiling

    Alexandra Resch;Stefan Leicht;Marc Saric;Linda Pásztor

  • An Exocyst Complex Functions in Plant Cell Growth in Arabidopsis and Tobacco

    Michal Hála;Rex Cole;Lukáš Synek;Edita Drdová

  • Bartonella Adhesin A Mediates a Proangiogenic Host Cell Response

    Tanja Riess;Siv G.E. Andersson;Andrei Lupas;Martin Schaller

  • Right-handed and left-handed DNA: studies of B- and Z-DNA by using proton nuclear Overhauser effect and P NMR

    Dinshaw J. Patel;Sharon A. Kozlowski;Alfred Nordheim;Alexander Rich

  • Gene regulation by Ets proteins

    Ralf Janknecht;Alfred Nordheim

  • An Exocyst Complex Functions in Plant Cell Growth in

    Michal Hala;Rex Cole;Alfred Nordheim;Tobias Lamkemeyer

Frequent Co-Authors

Frank Hochholdinger
Frank Hochholdinger University of Bonn
Robert Geffers
Robert Geffers Helmholtz Centre for Infection Research
Eric N. Olson
Eric N. Olson The University of Texas Southwestern Medical Center
Peter Schirmacher
Peter Schirmacher University Hospital Heidelberg
B D Stollar
B D Stollar Tufts University
Heinz Schwarz
Heinz Schwarz Max Planck Society
Rejko Krüger
Rejko Krüger University of Luxembourg
Eileen M. Lafer
Eileen M. Lafer The University of Texas Health Science Center at San Antonio

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