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D-Index & Metrics

Biology and Biochemistry

D-Index
75
Citations
18119
World Ranking
5378
National Ranking
2549

Research.com Recognitions

  • 2001 - Fellow of Alfred P. Sloan Foundation

Overview

Aaron DiAntonio is affiliated with Washington University in St. Louis in the United States. Their research primarily spans the fields of Biochemistry, Genetics and Molecular Biology; Medicine; and Neuroscience. Within these fields, their work covers notable subfields such as Molecular Biology, Cellular and Molecular Neuroscience, Cell Biology, Physiology, and Neurology.

The scientist has contributed extensively to multiple topics, including Endoplasmic Reticulum Stress and Disease, Sirtuins and Resveratrol in Medicine, Calcium signaling and nucleotide metabolism, Signaling Pathways in Disease, Nerve injury and regeneration, Amyotrophic Lateral Sclerosis Research, and Retinal Development and Disorders.

Aaron DiAntonio has published in various scientific venues with frequent appearances in bioRxiv (Cold Spring Harbor Laboratory), Cell Reports, Experimental Neurology, eLife, and The Journal of Cell Biology. Their collaborative work involves frequent co-authorship with researchers such as Jeffrey Milbrandt, Yo Sasaki, Amy Strickland, A. Joseph Bloom, and Yurie Yamada.

Selected recent papers include:

  • SARM1 is a metabolic sensor activated by an increased NMN/NAD+ ratio to trigger axon degeneration, 2021, Neuron
  • Small Molecule SARM1 Inhibitors Recapitulate the SARM1−/− Phenotype and Allow Recovery of a Metastable Pool of Axons Fated to Degenerate, 2021, Cell Reports
  • The SARM1 axon degeneration pathway: control of the NAD+ metabolome regulates axon survival in health and disease, 2020, Current Opinion in Neurobiology
  • Cyclic ADP ribose isomers: Production, chemical structures, and immune signaling, 2022, Science
  • SARM1 acts downstream of neuroinflammatory and necroptotic signaling to induce axon degeneration, 2020, The Journal of Cell Biology

Among awards, Aaron DiAntonio received recognition as a Fellow of the Alfred P. Sloan Foundation in 2001.

Best Publications

  • Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition)

    Daniel J. Klionsky;Kotb Abdelmohsen;Akihisa Abe;Joynal Abedin

  • Genetic Analysis of Glutamate Receptors in Drosophila Reveals a Retrograde Signal Regulating Presynaptic Transmitter Release

    Sophie A Petersen;Richard D Fetter;Jasprina N Noordermeer;Corey S Goodman

  • SARM1 activation triggers axon degeneration locally via NAD+ destruction

    Josiah Gerdts;E.J. Brace;Yo Sasaki;Aaron DiAntonio

  • The SARM1 Toll/Interleukin-1 Receptor Domain Possesses Intrinsic NAD+ Cleavage Activity that Promotes Pathological Axonal Degeneration

    Kow Essuman;Daniel W. Summers;Yo Sasaki;Xianrong Mao

  • Highwire regulates synaptic growth in Drosophila.

    Hong I. Wan;Aaron DiAntonio;Richard D. Fetter;Kendra Bergstrom

  • Ubiquitination-dependent mechanisms regulate synaptic growth and function

    Aaron DiAntonio;Ali P. Haghighi;Scott L. Portman;Jason D. Lee

  • TIR domains of plant immune receptors are NAD+-cleaving enzymes that promote cell death

    Li Wan;Kow Essuman;Ryan G. Anderson;Yo Sasaki

  • Increased Expression of the Drosophila Vesicular Glutamate Transporter Leads to Excess Glutamate Release and a Compensatory Decrease in Quantal Content

    Richard W. Daniels;Catherine A. Collins;Maria V. Gelfand;Jaime Dant

  • Highwire restrains synaptic growth by attenuating a MAP kinase signal.

    Catherine A. Collins;Yogesh P. Wairkar;Sylvia L. Johnson;Aaron DiAntonio

  • Sarm1-mediated axon degeneration requires both SAM and TIR interactions.

    Josiah Gerdts;Daniel W. Summers;Yo Sasaki;Aaron DiAntonio

  • Glutamate Receptor Expression Regulates Quantal Size and Quantal Content at the Drosophila Neuromuscular Junction

    Aaron DiAntonio;Sophie A. Petersen;Manfred Heckmann;Corey S. Goodman

  • Differential Localization of Glutamate Receptor Subunits at the Drosophila Neuromuscular Junction

    Scott B. Marrus;Scott L. Portman;Marcus James Allen;Kevin G. Moffat

  • Dual Leucine Zipper Kinase Is Required for Retrograde Injury Signaling and Axonal Regeneration

    Jung Eun Shin;Yongcheol Cho;Bogdan Beirowski;Jeffrey Milbrandt

  • Synaptic transmission persists in synaptotagmin mutants of Drosophila

    Aaron DiAntonio;Karen D. Parfitt;Thomas L. Schwarz

  • A dual leucine kinase-dependent axon self-destruction program promotes Wallerian degeneration.

    Bradley R Miller;Craig Press;Richard W Daniels;Yo Sasaki

  • Axon Self-Destruction: New Links among SARM1, MAPKs, and NAD+ Metabolism

    Josiah Gerdts;Daniel W. Summers;Jeffrey Milbrandt;Aaron DiAntonio

  • The effect on synaptic physiology of synaptotagmin mutations in drosophila

    Aaron DiAntonio;Thomas L. Schwarz

  • Synaptic development: insights from Drosophila.

    Catherine A Collins;Aaron DiAntonio

  • Absence of synaptotagmin disrupts excitation-secretion coupling during synaptic transmission

    K Broadie;H J Bellen;A DiAntonio;J T Littleton

  • Protein turnover of the Wallenda/DLK kinase regulates a retrograde response to axonal injury

    Xin Xiong;Xin Wang;Ronny Ewanek;Pavan Bhat;Pavan Bhat

Frequent Co-Authors

Thomas Schwarz
Thomas Schwarz Boston Children's Hospital
Corey S. Goodman
Corey S. Goodman University of California, Berkeley
Robert W. Burgess
Robert W. Burgess The Jackson Laboratory
Lawrence B. Holzman
Lawrence B. Holzman University of Pennsylvania
Rosalind A. Segal
Rosalind A. Segal Harvard University
Maria Leptin
Maria Leptin University of Cologne
Graeme W. Davis
Graeme W. Davis University of California, San Francisco
Richard D. Fetter
Richard D. Fetter University of California, San Francisco
Hao Wu
Hao Wu Harvard University
Jeffery L. Dangl
Jeffery L. Dangl University of North Carolina at Chapel Hill

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