Xin-Yun Huang

Research.com Recognitions

• 2012 - Fellow of the American Association for the Advancement of Science (AAAS)

Overview

Best Publications

• Orai1 and STIM1 Are Critical for Breast Tumor Cell Migration and Metastasis

  Shengyu Yang;J. Jillian Zhang;Xin Yun Huang

  787
  Citations

• Src tyrosine kinase is a novel direct effector of G proteins.

  Yong Chao Ma;Jianyun Huang;Shariq Ali;William Lowry

  524
  Citations

• Structural Basis for Relief of Autoinhibition of the Dbl Homology Domain of Proto-Oncogene Vav by Tyrosine Phosphorylation

  Behzad Aghazadeh;William E. Lowry;Xin Yun Huang;Michael K. Rosen;Michael K. Rosen

  476
  Citations

• Binding of Src to Na+/K+-ATPase forms a functional signaling complex.

  Jiang Tian;Ting Cai;Zhaokan Yuan;Haojie Wang

  446
  Citations

• Regulation, Signaling, and Physiological Functions of G-Proteins.

  Viktoriya Syrovatkina;Kamela O. Alegre;Raja Dey;Xin Yun Huang

  439
  Citations

• Tyrosine kinases in activation of the MAP kinase cascade by G-protein-coupled receptors

  Yong Wan;Tomohiro Kurosaki;Xin Yun Huang

  399
  Citations

• Tyrosine kinase-dependent suppression of a potassium channel by the G protein-coupled m1 muscarinic acetylcholine receptor

  Xin-Yun Huang;Anthony D. Morielli;Ernest G. Peralta

  334
  Citations

• Crystal structure of oligomeric β1-adrenergic G protein–coupled receptors in ligand-free basal state

  Jianyun Huang;Shuai Chen;J Jillian Zhang;Xin-Yun Huang

  331
  Citations

• Migrastatin analogues target fascin to block tumour metastasis

  Lin Chen;Shengyu Yang;Jean Jakoncic;J. Jillian Zhang

  309
  Citations

• Leucine-rich repeat kinase 2 (LRRK2)/PARK8 possesses GTPase activity that is altered in familial Parkinson's disease R1441C/G mutants.

  Xianting Li;Yin-Cai Tan;Shibu Poulose;C. Warren Olanow

  295
  Citations

• RGS-PX1, a GAP for Gαs and sorting nexin in vesicular trafficking

  Bin Zheng;Yong-Chao Ma;Rennolds S. Ostrom;Christine Lavoie

  282
  Citations

• Direct stimulation of Bruton's tyrosine kinase by G q -protein α-subunit

  Kendra Bence;Wei Ma;Tohru Kozasa;Xin-Yun Huang

  267
  Citations

• The G protein Gα12 stimulates Bruton's tyrosine kinase and a rasGAP through a conserved PH/BM domain

  Yun Jiang;Wei Ma;Yong Wan;Tohru Kozasa

  265
  Citations

• Overall survival with sunitinib versus interferon (IFN)-alfa as first-line treatment of metastatic renal cell carcinoma (mRCC)

  R. A. Figlin;T. E. Hutson;P. Tomczak;M. D. Michaelson

  231
  Citations

• Discovery of potent cell migration inhibitors through total synthesis: lessons from structure-activity studies of (+)-migrastatin.

  Jón T. Njardarson;Christoph Gaul;Dandan Shan;Xin Yun Huang

  226
  Citations

• The Migrastatin Family: Discovery of Potent Cell Migration Inhibitors by Chemical Synthesis

  Christoph Gaul;Jón T. Njardarson;Dandan Shan;David C. Dorn

  217
  Citations

• A second trans-spliced RNA leader sequence in the nematode Caenorhabditis elegans.

  Xin-Yun Huang;David Hirsh

  199
  Citations

• Synthetic analogues of migrastatin that inhibit mammary tumor metastasis in mice

  Dandan Shan;Lin Chen;Jon T. Njardarson;Christoph Gaul

  198
  Citations

• Prognostic factors for progression-free and overall survival with sunitinib targeted therapy and with cytokine as first-line therapy in patients with metastatic renal cell carcinoma

  S. Patil;R.A. Figlin;T.E. Hutson;M.D. Michaelson

  198
  Citations

• Activation of Tsk and Btk tyrosine kinases by G protein beta gamma subunits.

  Sigrid A. Langhans-Rajasekaran;Yong Wan;Xin Yun Huang

  188
  Citations