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Biology and Biochemistry

D-Index
67
Citations
16100
World Ranking
8221
National Ranking
3714

Overview

Zijian Xie is affiliated with Marshall University in the United States, where their research spans biochemistry, genetics, and molecular biology, with a substantial focus on medicine. Their work covers molecular biology extensively, complemented by investigations in surgery, cardiology and cardiovascular medicine, cell biology, and endocrinology, diabetes, and metabolism.

The research topics Zijian Xie engages with include ion transport and channel regulation, pancreatic function and diabetes, magnesium in health and disease, adipose tissue and metabolism, Caveolin-1 and cellular processes, hormonal regulation and hypertension, as well as heart failure treatment and management.

Zijian Xie has contributed to multiple research articles, among which the following notable publications are included:

  • The Role of Histone Acetylation-/Methylation-Mediated Apoptotic Gene Regulation in Hepatocellular Carcinoma (2020) published in International Journal of Molecular Sciences
  • Phenylethanoid glycosides of Callicarpa kwangtungensis Chun exert cardioprotective effect by weakening Na+-K+-ATPase/Src/ERK1/2 pathway and inhibiting apoptosis mediated by oxidative stress and inflammation (2020) published in Journal of Ethnopharmacology
  • The Na/K-ATPase α1/Src interaction regulates metabolic reserve and Western diet intolerance (2021) published in Acta Physiologica
  • Regulation of Myogenesis by a Na/K-ATPase α1 Caveolin-Binding Motif (2022) published in Stem Cells
  • Central Role for Adipocyte Na,K-ATPase Oxidant Amplification Loop in the Pathogenesis of Experimental Uremic Cardiomyopathy (2020) published in Journal of the American Society of Nephrology

The frequent publication venues for Zijian Xie include:

  • The FASEB Journal
  • International Journal of Molecular Sciences
  • Journal of the American Society of Nephrology
  • American Journal of Physiology-Cell Physiology
  • Cellular and Molecular Biology

Zijian Xie has collaborated extensively with other researchers. Frequent coauthors include:

  • Sandrine V. Pierre
  • Joseph I. Shapiro
  • Liquan Cai
  • Komal Sodhi
  • Xiaoliang Wang

Their research contributions address various aspects of cellular and molecular mechanisms, notably focusing on ion transport involving Na/K-ATPase and associated signaling pathways. This has implications for metabolic regulation, cardiovascular health, and cellular apoptosis processes.

Overall, Zijian Xie's body of work reflects sustained involvement in interdisciplinary biomedical research, particularly bridging molecular biology with cardiovascular and metabolic health.

Best Publications

  • Na+/K+-ATPase as a signal transducer

    Zijian Xie;Amir Askari

  • Na+-K+--ATPase-mediated signal transduction: from protein interaction to cellular function.

    Zijian Xie;Ting Cai

  • Involvement of Src and Epidermal Growth Factor Receptor in the Signal-transducing Function of Na+/K+-ATPase

    Michael Haas;Amir Askari;Zijian Xie

  • Na/K-ATPase Y260 Phosphorylation-mediated Src Regulation in Control of Aerobic Glycolysis and Tumor Growth

    Moumita Banerjee;Xiaoyu Cui;Zhichuan Li;Hui Yu;Hui Yu

  • Ouabain interaction with cardiac Na+/K+-ATPase initiates signal cascades independent of changes in intracellular Na+ and Ca2+ concentrations.

    Jiang Liu;Jiang Tian;Michael Haas;Joseph I. Shapiro

  • Multiple Signal Transduction Pathways Link Na+/K+-ATPase to Growth-related Genes in Cardiac Myocytes: THE ROLES OF Ras AND MITOGEN-ACTIVATED PROTEIN KINASES *

    Peter Kometiani;Jie Li;Luigi Gnudi;Barbara B. Kahn

  • Binding of Src to Na+/K+-ATPase forms a functional signaling complex.

    Jiang Tian;Ting Cai;Zhaokan Yuan;Haojie Wang

  • Mitochondrial potassium transport: the role of the mitochondrial ATP-sensitive K+ channel in cardiac function and cardioprotection

    Keith D Garlid;Pierre Dos Santos;Zi-Jian Xie;Alexandre D.T Costa

  • Bak regulates mitochondrial morphology and pathology during apoptosis by interacting with mitofusins

    Craig Brooks;Qingqing Wei;Leping Feng;Guie Dong

  • Intracellular Reactive Oxygen Species Mediate the Linkage of Na+/K+-ATPase to Hypertrophy and its Marker Genes in Cardiac Myocytes

    Zijian Xie;Peter Kometiani;Jiang Liu;Jie Li

  • Src-mediated Inter-receptor Cross-talk between the Na+/K+-ATPase and the Epidermal Growth Factor Receptor Relays the Signal from Ouabain to Mitogen-activated Protein Kinases

    Michael Haas;Haojie Wang;Jiang Tian;Zijian Xie

  • Ouabain Assembles Signaling Cascades through the Caveolar Na+/K+-ATPase *

    Haojie Wang;Michael Haas;Man Liang;Ting Cai

  • Central Role for the Cardiotonic Steroid Marinobufagenin in the Pathogenesis of Experimental Uremic Cardiomyopathy

    David J. Kennedy;Sandeep Vetteth;Sankaridrug M. Periyasamy;Mohamed Kanj

  • Identification of a pool of non-pumping Na/K-ATPase.

    Man Liang;Jiang Tian;Lijun Liu;Sandrine Pierre

  • Na/K-ATPase Tethers Phospholipase C and IP3 Receptor into a Calcium-regulatory Complex

    Zhaokan Yuan;Ting Cai;Jiang Tian;Alexander V. Ivanov

  • Molecular Mechanisms of Na/K-ATPase-Mediated Signal Transduction

    Zijian Xie

  • The Na/K-ATPase/Src complex and cardiotonic steroid-activated protein kinase cascades.

    Zhichuan Li;Zijian Xie

  • Partial inhibition of Na+/K+-ATPase by ouabain induces the Ca2+-dependent expressions of early-response genes in cardiac myocytes.

    Ming Peng;Liuyu Huang;Zijian Xie;Wu-Hsiung Huang

  • Role of caveolae in signal-transducing function of cardiac Na+/K+-ATPase.

    Lijun Liu;Kamiar Mohammadi;Behrouz Aynafshar;Haojie Wang

  • Ouabain induces endocytosis of plasmalemmal Na/K-ATPase in LLC-PK1 cells by a clathrin-dependent mechanism.

    Jiang Liu;Riad Kesiry;Sankaridrug M. Periyasamy;Deepak Malhotra

Frequent Co-Authors

Roy L. Silverstein
Roy L. Silverstein Medical College of Wisconsin
Juan Sanabria
Juan Sanabria Marshall University
Jerry B. Lingrel
Jerry B. Lingrel University of Cincinnati
Christian Aalkjaer
Christian Aalkjaer Aarhus University
W.H. Wilson Tang
W.H. Wilson Tang Cleveland Clinic
Keith D. Garlid
Keith D. Garlid Portland State University
Xiaochun Wan
Xiaochun Wan Anhui Agricultural University
Nader G. Abraham
Nader G. Abraham New York Medical College
Fayez K. Ghishan
Fayez K. Ghishan University of Arizona
Barbara B. Kahn
Barbara B. Kahn Beth Israel Deaconess Medical Center

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