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Chemistry

D-Index
56
Citations
7599
World Ranking
11947
National Ranking
3205

Overview

George A. O'Doherty is a researcher affiliated with Northeastern University in the United States. Their work spans several interconnected scientific fields, primarily focusing on Biochemistry, Genetics and Molecular Biology, Chemistry, and Medicine.

Within these fields, O'Doherty has contributed extensively to subfields such as Molecular Biology, Organic Chemistry, Pharmacology, Inorganic Chemistry, and Biochemistry. Their research topics cover diverse areas including Carbohydrate Chemistry and Synthesis, Microbial Natural Products and Biosynthesis, Glycosylation and Glycoproteins Research, Chemical Synthesis and Analysis, Synthetic Organic Chemistry Methods, Ion Transport and Channel Regulation, and Asymmetric Hydrogenation and Catalysis.

O'Doherty's publication record includes papers in several prominent scientific journals. Notable recent papers include:

  • New strategies and structural considerations in development of therapeutics for carbapenem-resistant Enterobacteriaceae, 2020, Translational Research
  • Synthesis and Biological Evaluation of 4'-Substituted Kaempfer-3-ols, 2020, The Journal of Organic Chemistry
  • De novo asymmetric Achmatowicz approach to oligosaccharide natural products, 2022, Chemical Communications
  • Structure-activity relationship of avocadyne, 2021, Food & Function
  • Potential antitumor activity of digitoxin and user-designed analog administered to human lung cancer cells, 2020, Biochimica et Biophysica Acta (BBA) - General Subjects

Frequent co-authors collaborating with O'Doherty include Sugyeom Kim, Yu Li, James E. Kirby, Deborah A. Lannigan, and Alhanouf Z. Aljahdali. The working relationships suggest a strong interdisciplinary and collaborative research approach.

O'Doherty has published multiple articles in key scientific venues, such as:

  • Chemical Communications
  • Translational Research
  • The Journal of Organic Chemistry
  • Organic Letters
  • ACS Chemical Biology

Best Publications

  • A Palladium-Catalyzed Glycosylation Reaction: The de Novo Synthesis of Natural and Unnatural Glycosides

    Ravula Satheesh Babu;George A. O'doherty

  • De novo synthesis of oligosaccharides using a palladium-catalyzed glycosylation reaction.

    Ravula Satheesh Babu;Maoquan Zhou;George A. O'Doherty

  • Synthesis of D- and L-deoxymannojirimycin via an asymmetric aminohydroxylation of vinylfuran.

    Michael H. Haukaas;George A. O'Doherty

  • Asymmetric synthesis of allylic sulfones useful as asymmetric building blocks.

    Barry M. Trost;Michael G. Organ;George A. O'Doherty

  • Syntheses of D- and L-Mannose, Gulose, and Talose via Diastereoselective and Enantioselective Dihydroxylation Reactions.

    Harris Jm;Keranen;O'Doherty Ga

  • De novo approach to 2-deoxy-beta-glycosides: asymmetric syntheses of digoxose and digitoxin.

    Maoquan Zhou;George A. O’Doherty

  • De Novo Asymmetric Synthesis of the Anthrax Tetrasaccharide by a Palladium‐Catalyzed Glycosylation Reaction

    Haibing Guo;George A. O'Doherty

  • Enantioselective Synthesis of 2-Deoxy- and 2,3-Dideoxyhexoses

    Michael H. Haukaas;George A. O'Doherty

  • Syntheses of four D- and L-hexoses via diastereoselective and enantioselective dihydroxylation reactions.

    Joel M. Harris;Mark D. Keränen;Hang Nguyen;Victor G. Young

  • A direct comparison of the anticancer activities of digitoxin MeON-Neoglycosides and O-Glycosides

    Anand Krishnan V. Iyer;Maoquan Zhou;Neelam Azad;Hosam Elbaz

  • De novo asymmetric synthesis of D- and L-swainsonine.

    Haibing Guo;George A. O'Doherty

  • De novo asymmetric synthesis of all-D-, all-L-, and D-/L-oligosaccharides using atom-less protecting groups.

    Ravula Satheesh Babu;Qian Chen;Sang-Woo Kang;Maoquan Zhou

  • A stereoselective synthesis of digitoxin and digitoxigen mono- and bisdigitoxoside from digitoxigenin via a palladium-catalyzed glycosylation.

    Maoquan Zhou;George A. O’Doherty

  • De novo enantioselective syntheses of galacto-sugars and deoxy sugars via the iterative dihydroxylation of dienoate.

    Md. Moinuddin Ahmed;Bryan P. Berry;Thomas J. Hunter;Dennis J. Tomcik

  • De novo asymmetric synthesis of anthrax tetrasaccharide and related tetrasaccharide.

    Haibing Guo;George A. O’Doherty

  • Stereochemical survey of digitoxin monosaccharides: new anticancer analogues with enhanced apoptotic activity and growth inhibitory effect on human non-small cell lung cancer cell

    Hua Yu Leo Wang;Wenjun Xin;Maoquan Zhou;Todd A. Stueckle

  • De novo synthesis of the trisaccharide subunit of landomycins A and E.

    Maoquan Zhou;George A. O’Doherty

  • Sharpless Asymmetric Dihydroxylation of 5-Aryl-2-vinylfurans: Application to the Synthesis of the Spiroketal Moiety of Papulacandin D

    Devan Balachari;George A. O'Doherty

  • Synthesis and Evaluation of the α-d-/α-l-Rhamnosyl and Amicetosyl Digitoxigenin Oligomers as Antitumor Agents

    Hua Yu Leo Wang;Yon Rojanasakul;George A. O'Doherty

  • de novo asymmetric synthesis of daumone via a palladium-catalyzed glycosylation.

    Haibing Guo;George A. O'Doherty

  • Synthesis of 7-oxa-phomopsolide E and its C-4 epimer

    Miaosheng Li;Jana Scott;George A. O’Doherty

Frequent Co-Authors

Joel M. Harris
Joel M. Harris University of Utah
Yon Rojanasakul
Yon Rojanasakul West Virginia University
Leo A. Paquette
Leo A. Paquette The Ohio State University
Robin D. Rogers
Robin D. Rogers University of Alabama
Geoffrey W. Coates
Geoffrey W. Coates Cornell University
Xue-Bin Wang
Xue-Bin Wang Pacific Northwest National Laboratory
Barry M. Trost
Barry M. Trost Stanford University
Sidney M. Hecht
Sidney M. Hecht Arizona State University
Victor G. Young
Victor G. Young University of Minnesota
Todd L. Lowary
Todd L. Lowary University of Alberta

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