What is he best known for?
The fields of study he is best known for:
W. J. Pledger spends much of his time researching Growth factor, Cell biology, Platelet-derived growth factor receptor, Platelet-derived growth factor and Molecular biology.
His Growth factor research includes elements of Cell cycle, Cell culture, Epidermal growth factor and DNA synthesis.
His Cell culture research focuses on subjects like Endocrinology, which are linked to Fibroblast growth factor and Cell growth.
His research integrates issues of Integrin, Biochemistry and Neural cell adhesion molecule in his study of Cell biology.
The various areas that W. J. Pledger examines in his Platelet-derived growth factor receptor study include Cancer research, Cyclin, Phosphorylation and Ectopic expression.
His research in Platelet-derived growth factor intersects with topics in STAT3, Signal transduction, STAT protein and Proto-oncogene tyrosine-protein kinase Src.
His most cited work include:
- Dual control of cell growth by somatomedins and platelet-derived growth factor (795 citations)
- Induction of DNA synthesis in BALB/c 3T3 cells by serum components: Reevaluation of the commitment process (556 citations)
- Stat3-mediated Myc expression is required for Src transformation and PDGF-induced mitogenesis (424 citations)
What are the main themes of his work throughout his whole career to date?
W. J. Pledger mainly investigates Cell biology, Growth factor, Platelet-derived growth factor receptor, Molecular biology and Platelet-derived growth factor.
His Cell biology research integrates issues from Immunology, Cell cycle, Insulin and Cell growth.
His Growth factor research is multidisciplinary, relying on both Cell culture, Epidermal growth factor, Endocrinology and DNA synthesis.
He has researched Cell culture in several fields, including Fibroblast growth factor and Protein biosynthesis.
His work is dedicated to discovering how Platelet-derived growth factor receptor, Tyrosine phosphorylation are connected with Tyrosine kinase and other disciplines.
His work deals with themes such as Cyclin A, Cyclin D3, Cyclin and Intracellular, which intersect with Molecular biology.
He most often published in these fields:
- Cell biology (47.19%)
- Growth factor (47.19%)
- Platelet-derived growth factor receptor (42.70%)
What were the highlights of his more recent work (between 1994-2013)?
- Cell biology (47.19%)
- Cyclin-dependent kinase (10.11%)
- Cyclin (8.99%)
In recent papers he was focusing on the following fields of study:
The scientist’s investigation covers issues in Cell biology, Cyclin-dependent kinase, Cyclin, Cyclin A and Molecular biology.
He does research in Cell biology, focusing on Fibronectin specifically.
His Cyclin study necessitates a more in-depth grasp of Cell cycle.
His work carried out in the field of Cyclin A brings together such families of science as Cyclin-dependent kinase complex, Cyclin D, Cyclin A2 and Cyclin B.
As part of the same scientific family, he usually focuses on Molecular biology, concentrating on Cyclin D3 and intersecting with Psychological repression and Cyclin D2.
His Cancer research research focuses on STAT protein and how it connects with Platelet-derived growth factor receptor.
Between 1994 and 2013, his most popular works were:
- Stat3-mediated Myc expression is required for Src transformation and PDGF-induced mitogenesis (424 citations)
- Phosphatidylinositol 3-Kinase/Akt Pathway Regulates Tuberous Sclerosis Tumor Suppressor Complex by Phosphorylation of Tuberin (348 citations)
- Adhesion to fibronectin via beta1 integrins regulates p27kip1 levels and contributes to cell adhesion mediated drug resistance (CAM-DR). (300 citations)
In his most recent research, the most cited papers focused on:
His primary scientific interests are in Cell biology, Cyclin E, Cyclin B, Cyclin A and Cyclin-dependent kinase complex.
His Cell biology research is multidisciplinary, incorporating perspectives in Integrin and Cell adhesion, Neural cell adhesion molecule.
His work carried out in the field of Cyclin B brings together such families of science as Cyclin-dependent kinase, Cyclin A2 and Cyclin D.
His Cyclin D1 study which covers Cancer research that intersects with Proto-oncogene tyrosine-protein kinase Src, Ectopic expression, Signal transduction and STAT3.
The various areas that he examines in his Platelet-derived growth factor study include Cyclin D2 and Cyclin.
His Platelet-derived growth factor receptor research entails a greater understanding of Growth factor.
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