What is he best known for?
The fields of study he is best known for:
- Enzyme
- Biochemistry
- Internal medicine
The scientist’s investigation covers issues in Cell biology, Biochemistry, Receptor, Pathology and Fibronectin.
The various areas that Edward J. O'Keefe examines in his Cell biology study include Desmoplakin, Growth factor, Adherens junction and Keratinocyte.
His work on Growth factor receptor inhibitor, Cyclase activity and Cyclase as part of general Receptor research is often related to Choleragenoid, thus linking different fields of science.
Edward J. O'Keefe does research in Pathology, focusing on Basement membrane specifically.
His studies in Fibronectin integrate themes in fields like Anatomy, Matrix and Motility.
His Epidermal growth factor study combines topics from a wide range of disciplines, such as Molecular biology, Endocrinology and Dissociation constant.
His most cited work include:
- Identification of the Skin Basement-Membrane Autoantigen in Epidermolysis Bullosa Acquisita (422 citations)
- Epidermal growth factor. Characteristics of specific binding in membranes from liver, placenta, and other target tissues. (207 citations)
- Burn wounds resurfaced by cultured epidermal autografts show abnormal reconstitution of anchoring fibrils. (180 citations)
What are the main themes of his work throughout his whole career to date?
His scientific interests lie mostly in Cell biology, Molecular biology, Epidermal growth factor, Biochemistry and Keratinocyte.
His study in Cell biology is interdisciplinary in nature, drawing from both Wound healing and Adherens junction.
His research integrates issues of Antibody, Virology, Collagenase and Basement membrane in his study of Molecular biology.
His Basement membrane research is multidisciplinary, relying on both Immunology and Antigen.
The concepts of his Epidermal growth factor study are interwoven with issues in Endocrinology, Growth factor and Epidermal growth factor receptor.
His Biochemistry research is multidisciplinary, incorporating perspectives in Type I collagen and Cholera toxin.
He most often published in these fields:
- Cell biology (33.73%)
- Molecular biology (32.53%)
- Epidermal growth factor (28.92%)
What were the highlights of his more recent work (between 1991-2006)?
- Cell biology (33.73%)
- Adherens junction (8.43%)
- Molecular biology (32.53%)
In recent papers he was focusing on the following fields of study:
Edward J. O'Keefe spends much of his time researching Cell biology, Adherens junction, Molecular biology, Desmosome and Vinculin.
By researching both Cell biology and Plakoglobin, Edward J. O'Keefe produces research that crosses academic boundaries.
His Adherens junction research is included under the broader classification of Biochemistry.
Edward J. O'Keefe interconnects Calcium-binding protein and Keratinocyte in the investigation of issues within Molecular biology.
His Desmosome research includes elements of Stratum corneum, Galectin 4, Epidermis and β galactoside binding lectin.
He combines subjects such as Hemidesmosome, Extracellular matrix and Cell junction with his study of Vinculin.
Between 1991 and 2006, his most popular works were:
- Human autoantibodies against desmoplakins in paraneoplastic pemphigus. (158 citations)
- Human Keratinocyte Locomotion: The Effect of Selected Cytokines (88 citations)
- Re-epithelialization. Human keratinocyte locomotion. (79 citations)
In his most recent research, the most cited papers focused on:
- Enzyme
- Biochemistry
- Internal medicine
His main research concerns Cell biology, Biochemistry, Desmosome, Pathology and Keratinocyte.
Edward J. O'Keefe performs integrative Cell biology and Plakoglobin research in his work.
His study in the fields of Lectin, Adherens junction, Lactose binding and C-type lectin under the domain of Biochemistry overlaps with other disciplines such as Trichohyalin.
The study incorporates disciplines such as Desmoplakins, Stratum corneum, Stratum granulosum and Epidermis in addition to Desmosome.
His work deals with themes such as Autoantibody, Paraneoplastic pemphigus, Antibody, Autoimmunity and Pemphigus, which intersect with Pathology.
His research in Keratinocyte intersects with topics in Connective tissue, Cell division, Re-epithelialization, Process and Epidermis.
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