D-Index & Metrics Best Publications

D-Index & Metrics D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines.

Discipline name D-index D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines. Citations Publications World Ranking National Ranking
Biology and Biochemistry D-index 93 Citations 32,900 207 World Ranking 1358 National Ranking 800

Research.com Recognitions

Awards & Achievements

1988 - Fellow of the American Academy of Arts and Sciences

1982 - Member of the National Academy of Sciences

Overview

What is he best known for?

The fields of study he is best known for:

  • Enzyme
  • Biochemistry
  • Amino acid

Pedro Cuatrecasas mainly investigates Biochemistry, Receptor, Insulin, Binding site and Insulin receptor. Biochemistry is a component of his Phospholipase C, Protein kinase C, Arachidonic acid, Phospholipase A2 and Phosphorylation studies. His Receptor study incorporates themes from Molecular biology, Wheat germ agglutinin, Cholera toxin and Vibrio cholerae.

His Insulin research is multidisciplinary, incorporating elements of Affinity label and Cell membrane. Pedro Cuatrecasas has included themes like Plasma protein binding, Enkephalin, Molecular mass, Hormone and Cytotoxicity in his Binding site study. His work on Insulin receptor substrate as part of general Insulin receptor study is frequently connected to Interleukin 5 receptor alpha subunit, therefore bridging the gap between diverse disciplines of science and establishing a new relationship between them.

His most cited work include:

  • [31] Affinity chromatography (1433 citations)
  • Selective enzyme purification by affinity chromatography (891 citations)
  • Immunohistochemical localization of enkephalin in rat brain and spinal cord. (761 citations)

What are the main themes of his work throughout his whole career to date?

Pedro Cuatrecasas focuses on Biochemistry, Receptor, Endocrinology, Internal medicine and Insulin. His studies in Enzyme, Cyclase, Arachidonic acid, Adenylate kinase and Membrane are all subfields of Biochemistry research. His study on Arachidonic acid also encompasses disciplines like

  • Phosphatidic acid which connect with Phospholipase A2, Thrombin and Platelet,
  • Phospholipase, which have a strong connection to Diacylglycerol kinase.

His study in Receptor is interdisciplinary in nature, drawing from both Insulin receptor, Binding site and Cell biology. His work deals with themes such as Concanavalin A and Affinity chromatography, which intersect with Insulin receptor. His studies deal with areas such as Cell surface receptor, Internalization, Calmodulin and Cell membrane as well as Cell biology.

He most often published in these fields:

  • Biochemistry (65.24%)
  • Receptor (35.71%)
  • Endocrinology (14.76%)

What were the highlights of his more recent work (between 1984-2020)?

  • Biochemistry (65.24%)
  • Protein kinase A (8.10%)
  • Protein kinase C (5.71%)

In recent papers he was focusing on the following fields of study:

His primary areas of investigation include Biochemistry, Protein kinase A, Protein kinase C, Calmodulin and Cell biology. Much of his study explores Biochemistry relationship to Insulin. His research in Protein kinase A intersects with topics in Enzyme activator, Molecular biology and Cytoskeleton.

His research in Protein kinase C focuses on subjects like Phospholipase C, which are connected to Phospholipid, Diglyceride and Phosphatidylinositol. His Cell biology research integrates issues from Transferrin receptor and Growth factor. His work in PRKCQ tackles topics such as Receptor which are related to areas like Biophysics.

Between 1984 and 2020, his most popular works were:

  • A model for intracellular translocation of protein kinase C involving synergism between Ca2+ and phorbol esters. (401 citations)
  • Rapid formation of diacylglycerol from phosphatidylcholine: a pathway for generation of a second messenger. (326 citations)
  • Insulin-stimulated hydrolysis of a novel glycolipid generates modulators of cAMP phosphodiesterase. (312 citations)

In his most recent research, the most cited papers focused on:

  • Enzyme
  • Biochemistry
  • Amino acid

Pedro Cuatrecasas spends much of his time researching Biochemistry, Protein kinase C, Phosphorylation, Protein kinase A and Diacylglycerol kinase. Phorbol, Enzyme activator, Phospholipid, Phospholipase and Membrane are among the areas of Biochemistry where the researcher is concentrating his efforts. The various areas that he examines in his Phorbol study include PRKCQ, Receptor and Protein phosphorylation.

His biological study spans a wide range of topics, including Phosphatidylinositol, Diglyceride, Phospholipase C and Cell membrane. His work carried out in the field of Phospholipase brings together such families of science as Inositol, Insulin, Glycolipid, Phosphodiesterase and Metabolism. His Protein kinase A research incorporates themes from Molecular biology and Topoisomerase, Topoisomerase-II Inhibitor.

This overview was generated by a machine learning system which analysed the scientist’s body of work. If you have any feedback, you can contact us here.

Best Publications

[31] Affinity chromatography

Pedro Cuatrecasas;Christian B. Anfinsen.
Methods in Enzymology (1971)

2397 Citations

Selective enzyme purification by affinity chromatography

Pedro Cuatrecasas;Meir Wilchek;Christian B. Anfinsen.
Proceedings of the National Academy of Sciences of the United States of America (1968)

1496 Citations

Immunohistochemical localization of enkephalin in rat brain and spinal cord.

Madhabananda Sar;Walter E. Stumpf;Richard J. Miller;Kwen‐Jen ‐J Chang.
The Journal of Comparative Neurology (1978)

955 Citations

Gangliosides and membrane receptors for cholera toxin.

Pedro Cuatrecasas.
Biochemistry (1973)

680 Citations

Interaction of Vibrio cholerae enterotoxin with cell membranes

Pedro Cuatrecasas.
Biochemistry (1973)

663 Citations

A model for intracellular translocation of protein kinase C involving synergism between Ca2+ and phorbol esters.

Marlene Wolf;Harry LeVine;W. Stratford May;Pedro Cuatrecasas.
Nature (1985)

610 Citations

Adsorbents for affinity chromatography. Use of N-hydroxysuccinimide esters of agarose.

Pedro Cuatrecasas;Indu Parikh.
Biochemistry (1972)

590 Citations

Specific nonopiate receptors for beta-endorphin

Eli Hazum;Kwen-Jen Chang;Pedro Cuatrecasas.
Science (1979)

584 Citations

Multiple Opiate Receptors: Different Regional Distribution in the Brain and Differential Binding of Opiates and Opioid Peptides

Kwen-Jen Chang;Barrett R. Cooper;Eli Hazum;Pedro Cuatrecasas.
Molecular Pharmacology (1979)

580 Citations

Monoclonal antibodies to receptors for insulin and somatomedin-C.

F C Kull;S Jacobs;Y F Su;M E Svoboda.
Journal of Biological Chemistry (1983)

569 Citations

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